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The wrinkle review: study finds more evidence needed to compare anti-wrinkle drugs
June 1, 2016
Ottawa researchers are known around the world for conducting systematic reviews to rigorously compare different medical treatments, but occasionally they also use this expertise to answer important non-medical questions. For example, Dr. James Bonaparte recently led the first large-scale analysis to compare three common anti-wrinkle medications, including Botox. Each supposedly has different features, but it is unclear whether they actually affect patients differently. The systematic review and meta-analysis, published in
Plastic and Reconstructive Surgery
,
used a unique method to compare the three medications. It found that all three reduced wrinkles better than a placebo and had similar side effects, but no difference could be found between them. However, many of the studies had limitations, leaving the researchers to conclude that more studies are needed, particularly research that compares the medications head to head.
Authors:
James Bonaparte, David Ellis, Jason Quinn, Jessica Rabski, Brian Hutton.
Funders:
Allergan, Inc. Canada
The Ottawa Hospital: Inspired by research. Driven by compassion
The Ottawa Hospital is one of Canada’s largest learning and research hospitals with over 1,100 beds, approximately 12,000 staff and an annual budget of over $1.2 billion. Our focus on research and learning helps us develop new and innovative ways to treat patients and improve care. As a multi-campus hospital, affiliated with the University of Ottawa, we deliver specialized care to the Eastern Ontario region, but our techniques and research discoveries are adopted around the world. We engage the community at all levels to support our vision for better patient care.
University of Ottawa
The University of Ottawa is home to over 50,000 students, faculty and staff, who live, work and study in both French and English. Our campus is a crossroads of cultures and ideas, where bold minds come together to inspire game-changing ideas. We are one of Canada’s top 10 research universities—our professors and researchers explore new approaches to today’s challenges. One of a handful of Canadian universities ranked among the top 200 in the world, we attract exceptional thinkers and welcome diverse perspectives from across the globe. www.uottawa.ca
For further information, please contact
Amelia Buchanan
Senior Communication Specialist
Ottawa Hospital Research Institute
Office: 613-798-5555 x 73687
Cell: 613-297-8315
ambuchanan@ohri.ca