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Researchers to identify most promising stroke therapies for clinical trials
November 16, 2016
Stroke is the third leading cause of death in Canada, and is usually caused by a blood clot in the brain. Currently the only approved drug therapy is a protein called plasminogen activator (tPA), which dissolves the clot. However, researchers have found dozens of other compounds that can prevent brain cell death in animal models in combination with tPA. To get these therapies to patients faster, we need to prioritize which should go to clinical trials. Drs.
David Moher
and
Dale Corbett
were awarded $100,000 from the Canadian Institutes of Health Research to compare over 40 of these potential stroke treatments head-to-head in a systematic review. They hope their study will speed up the process of getting the most promising therapies to clinical trials.
Co-investigators:
Avey, Marc T; Gray, Laura; Griffin, Gilly; Hakim, Antoine M; Hill, Michael D; Howells, David W; Hutton, Brian E; Lalu, Manoj M; Macleod, Malcolm; McCann, Sarah; Sena, Emily
The Ottawa Hospital: Inspired by research. Driven by compassion
The Ottawa Hospital is one of Canada’s largest learning and research hospitals with over 1,100 beds, approximately 12,000 staff and an annual budget of over $1.2 billion. Our focus on research and learning helps us develop new and innovative ways to treat patients and improve care. As a multi-campus hospital, affiliated with the University of Ottawa, we deliver specialized care to the Eastern Ontario region, but our techniques and research discoveries are adopted around the world. We engage the community at all levels to support our vision for better patient care. See www.ohri.ca for more information about research at The Ottawa Hospital.
University of Ottawa
The University of Ottawa is home to over 50,000 students, faculty and staff, who live, work and study in both French and English. Our campus is a crossroads of cultures and ideas, where bold minds come together to inspire game-changing ideas. We are one of Canada’s top 10 research universities—our professors and researchers explore new approaches to today’s challenges. One of a handful of Canadian universities ranked among the top 200 in the world, we attract exceptional thinkers and welcome diverse perspectives from across the globe. www.uottawa.ca
For further information, please contact
Amelia Buchanan
Senior Communication Specialist
Ottawa Hospital Research Institute
Office: 613-798-5555 x 73687
Cell: 613-297-8315
ambuchanan@ohri.ca