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$20 million grant to fund safety evaluation of new blood thinners
October 12, 2016
Dr. Lana Castellucci and her American colleagues Drs. Tom Ortel and David Garcia have been awarded US$14.8 million ($20 million Canadian) by the Patient-Centered Outcomes Research Institute to test the safety and effectiveness of three blood thinners in a head-to-head trial. Patients who develop a potentially dangerous blood clot in their legs with no obvious cause need to take one of these medications for the rest of their lives to prevent more clots from forming. Most patients are prescribed warfarin, which costs pennies a day. However, patients on this drug need to have regular blood tests and watch for interactions with food and other medications. New drugs called rivaroxaban and apixaban reduce these problems and may have a lower risk of bleeding, but cost over $100 a month. The
60-centre clinical trial
will definitively prove whether these new drugs are as safe or as effective as warfarin.
The Ottawa Hospital: Inspired by research. Driven by compassion
The Ottawa Hospital is one of Canada’s largest learning and research hospitals with over 1,100 beds, approximately 12,000 staff and an annual budget of over $1.2 billion. Our focus on research and learning helps us develop new and innovative ways to treat patients and improve care. As a multi-campus hospital, affiliated with the University of Ottawa, we deliver specialized care to the Eastern Ontario region, but our techniques and research discoveries are adopted around the world. We engage the community at all levels to support our vision for better patient care. See www.ohri.ca for more information about research at The Ottawa Hospital.
University of Ottawa
The University of Ottawa is home to over 50,000 students, faculty and staff, who live, work and study in both French and English. Our campus is a crossroads of cultures and ideas, where bold minds come together to inspire game-changing ideas. We are one of Canada’s top 10 research universities—our professors and researchers explore new approaches to today’s challenges. One of a handful of Canadian universities ranked among the top 200 in the world, we attract exceptional thinkers and welcome diverse perspectives from across the globe. www.uottawa.ca
For further information, please contact
Amelia Buchanan
Senior Communication Specialist
Ottawa Hospital Research Institute
Office: 613-798-5555 x 73687
Cell: 613-297-8315
ambuchanan@ohri.ca