Guy Trudel
Clinician Investigator, Inflammation & Chronic Disease
Ottawa Hospital Research Institute
Professor of Medcine, Surgery and Biochemistry
University of Ottawa
Bone and Joint Research Laboratory
The Ottawa Hospital Rehabilitation Centre
MARROW Space Research
International Space Station Payload
Research Interests
- Musculoskeletal effects of immobility
- Joint contractures
- Tendinopathies
- Gene
expression in the capsule and cartilage in contractures
- Pannus
proliferation in contractures, histomorphometric and biological study
- Hematopoiesis
with immobility
Brief Biography
Dr. Guy Trudel runs a clinical practice
and research program in Ottawa Canada. His tertiary academic rehabilitation unit delivers rehabilitation care to
people after polytrauma and serious / complex medical and surgical complications.
For the past 20 years, as Director of the Bone and Joint Research Laboratory, Dr Trudel has pursued clinical
and laboratory-based research on 3 areas related to the musculoskeletal complications of immobility: joint
contractures, tendonopathies and fat accumulation in the bone marrow. Dr. Trudel’s Ottawa University
internationally collaborative team has published over 60 original papers during his tenure, with studies
supported by CIHR, Canadian, European and German Space Agencies.
Selected Publications
Guy Trudel, Gerd Melkus, Greg O.
Cron, Hakim Louati, Adnan Sheikh, Peder E.Z. Larson, Mark Schweitzer, Peter
Lapner, Hans K. Uhthoff, Odette Laneuville.
Ultra-high field imaging of the rabbit supraspinatus enthesis: a 4-week
time course after repair surgery and effect of channeling.
Journal of Magnetic
Resonance Imaging. 2017.
Campbell Mark, Laneuville Odette,
Guy Trudel. Knee flexion contractures
in patients with osteoarthritis: clinical features and histologic
characterization of the posterior capsule.
PM&R 12;466-73,
2015.
Mehdi Kordi, Daniel L. Belavý, Gabriele Armbrecht, Adnan Sheikh, Dieter
Felsenberg,
Guy Trudel. Loss and re-adaptation of lumbar
intervertebral disc water signal intensity after prolonged bedrest.
Journal of Musculoskeletal and Neuronal
Interactions. 15, 294-300; 2015.
Guy Trudel, Odette Laneuville Elizabeth
Coletta, Louis Goudreau, Hans K. Uhthoff.
Quantitative and Temporal Differential Recovery of
Articular and Muscular Limitations of Knee Joint Contractures; Results in a Rat
Model.
Journal of Applied Physiology. 177(7), 730-737, 2014.
Guy Trudel, Elisabeth Coletta, Ian
Cameron, Daniel L. Belavý, Martin Lecompte, Gabriele Armbrecht, Dieter Felsenberg, Hans
Uhthoff. Resistive exercises with or
without whole-body vibration prevent vertebral marrow fat accumulation during
60 days of head-down tilt bed rest in men.
Journal of Applied Physiology. 112:1824-1831,
2012.
Diseases, conditions and populations of interest
Research and clinical approaches