The Ottawa Hospital Research Institute’s 19th annual Research Day was a great success, with over 400 attendees packing the St. Elias Centre to capacity. Designed to highlight and celebrate the outstanding work of trainees and promote scientific interaction, the event featured 172 posters (with 152 competing for prizes) and 16 oral presentations.
Drs. Lauralyn McIntyre, Paul Albert, Duncan Stewart and Jocelyn Côté set the stage with introductory remarks. John Chafe and Drs. John Marshall and Adrian Krainer gave the keynote talks.
Prizes were awarded to the following trainees:
Oral Presentation Competition
Clinical: Kelly Farrah (Kednapa Thavorn group) Burden and Financial Impact of Sepsis in Ontario: A Population-based, Retrospective Cohort Study
Co-authors: Lauralyn McIntyre, Robert Talarico, Monica Taljaard, Dean Fergusson, Christopher J. Doig, Alan J. Forster, Doug Coyle, Kednapa Thavorn
1st: Michaela Lunn (Michael Schlossmacher group) Elucidating the role of lrrk2 kinase activity in the innate immune system
Co-authors: Bojan Shutinoski, Quinton Hake-Volling, Mansoureh Hakimi, Julianna Tomlinson, Earl Brown, Michael G. Schlossmacher
2nd: Daniel Robinson (Jeffrey Dilworth group) Promoter-proximal stalling of RNA-Polymerase II is required to regulate myoblast fate determination during myogenesis
Co-authors: Karen Adelman, Jeffrey Dilworth
3rd: Alex Lin (Michael Rudnicki group) Single Cell Analyses Identify a Novel Muscle Stem Cell Subpopulation
Co-authors: Morten Ritso, Kasun Kodippili, J. Manuel Hernández-Hernández, Michael A. Rudnicki
Postdoctoral and Clinical Fellow Poster Competition
Clinical: Benjamin Gershkovich (supervised by Lauralyn McIntyre) Physicians’ Knowledge, Attitudes and Beliefs about a Hospital Wide Cluster Cross Over Pragmatic Fluid Administration Trial: An Electronic Survey
Co-authors: Weijer, Charles; Taljaard, Monica; Brehault, Jamie; McArdle, Tracy; Schweitzer, Irwin; Cook, Deborah J; English, Shane W; Fergusson, Dean; Forster, Alan; Fox-Robichaud, Alison; Graham, Ian; Hawken, Steven; Iyengar, Akshai; Martin, Claudio; Marshall, John; Maybee, Alies; McDonald, Ellen; Menon, Kusum; McCartney, Colin; Muscedere, John; Saginur, Raphael; Seely, Andrew; Thavorn, Kednapa; McIntyre, Lauralyn
1st: Martin Kang (Bernard Thébaud group) A Novel Lung Tropic AAV Vector Dramatically Improves Survival and Surfactant Homeostasis in a Mouse Model of Inherited Surfactant B Deficiency
Co-authors: Laura P. van Lieshout, Liqun Xu, Jakob M. Domm, Arul Vadivel, Laurent Renesme, Christian Mühlfeld, Maria Hurskainen, Ivana Mizikova, Yanlong Pei, Claudia Milazzo, Chanele Cyr-Depauw, Jeffrey A Whitsett, Larry M Nogee, Sarah K. Wootton, Bernard Thébaud
2nd: Allison Tscherner (Jay Baltz group) Initiation of independent cell volume regulation in the mouse oocyte at ovulation
Co-authors: Jay Baltz
3rd: Nikolas Martin (John Bell group)
Co-authors: Mathieu JF Crupi, Giuseppe Pugliese, Ragunath Singaravelu, John C Bell
PhD Student Poster Competition
Clinical: Annemarie Dedek (Michael Hildebrand and Eve Tsai group) Sex-specific mechanisms of spinal hyperexcitability in the human and rat superficial dorsal horn
Co-authors: Jian Xu, Chaya M. Kandegedara, Louis-Étienne Lorenzo, Antoine G. Godin, Paul J. Lombroso, Yves De Koninck, Eve C. Tsai, Michael E. Hildebrand
1st: Peter Feige (Michael Rudnicki group) Molecular regulation of brown adipogenic lineage specification from muscle stem cells
Co-authors: Hang Yin, Hong Ming, Michael A. Rudnicki
2nd: Terry Suk (Maxime Rousseaux group) Mesenchymal stromal cell-derived small extracellular vesicles as a potential therapeutic for treatment of pulmonary arterial hypertension
Co-authors: Alejandro Caballero, Jean-Louis Parmasad, Steve Callaghan, Stephen Baird, Maxime Rousseaux
3rd: Alvin Tieu (Manoj Lalu and Duncan Stewart group) Are mesenchymal stem cell-derived extracellular vesicles a promising cell-free therapy? A comprehensive systematic review of preclinical methodology and outcomes
Co-authors: Manoj M Lalu, Duncan J Stewart, Mitchell Slobodian, Dean A Fergusson, Joshua Montroy, Dylan Burger, David S Allan
4th: Nicholas Cober (Duncan Stewart group) Mesenchymal stromal cell-derived small extracellular vesicles as a potential therapeutic for treatment of pulmonary arterial hypertension
Co-authors: Alvin Tieu, Yupu Deng, Katelynn Rowe, Manoj Lalu, Duncan J. Stewart
Master’s Students and Residents Poster Competition
Clinical: David Massicotte-Azarniouch (Greg Knoll group) The association of blood transfusions with adverse graft outcomes in kidney transplant patients: a retrospective cohort study.
Co-authors: Manish M. Sood, Dean A. Fergusson, Michaël Chassé, Alan Tinmouth, Greg Knoll
1st: Wensheng Tian (Ryan Russel group) Analysis of Autophagy Induction Through Detection of ATG16L1 Phosphorylation
Co-authors: Reham Alsaadi, Zhihao Guo, Alena Kalinina, Micaël Carrier, Marie-Eve Tremblay, Baptiste Lacoste, Diane Lagace, Ryan C. Russell
2nd: Haley Geertsma (Maxime Rousseaux group) Elucidating the pathogenic role of nuclear alpha-synuclein in a novel mouse model of Parkinson’s disease
Co-authors: Haley Geertsma, Steve Callaghan, Maxime Rousseaux
3rd: Hayam Bassam (Catherine Tsilfidis group) Phenotype characterization of Leber’s hereditary optic neuropathy mouse models
Co-authors: Adam Baker, Pamela Lagali, Douglas Wallace, Catherine Tsilfidis
4th: Aoife Reilly (Rashmi Kothary group) Characterization of Neurofilament Light Chain as a Potential Blood Biomarker for Spinal Muscular Atrophy
Co-authors: Simon Thebault, Marc-Olivier Deguise, Ariane Beauvais, Jodi Warman Chardon, Daniel Tessier, Vincent Tabard-Cossa, Rashmi Kothary
Undergraduate Students Poster Competition
Jean-Louis Parmasad (Maxime Rousseaux group) Reducing Pfkt1 as a therapeutic approach to decreasing alpha-Synuclein levels
Co-authors: Haley Geertsma, Steve Callaghan, Maxime Rousseaux
Dr. Goodman Cohen Summer Student Award
Grace Fox (Dean Fergusson and Manoj Lalu group) Building a platform for meaningful patient partnership to accelerate “bench-to-bedside” translation of promising new therapies"
Research Day Committee and Volunteers:
Dr. Paul Albert (Co-chair), Dr. Lauralyn McIntyre (Co-chair), Dr. Anouk Fortin, Dr. Tim Ramsay, Dr. Jay Baltz, Dr. Ketul Chaudhary, Jennifer Ganton, Dr. Luc Sabourin, Amelia Buchanan, Dr. Angela Crawley, Dr. Ian Lorimer, Dr. Duncan Stewart, Jennifer Valentino, Greg Canham, Heidi Hickey, Natasha Hollywood, Jaahnavi Dave, Melanie Genereaux, Adrienne Szalamin, Wayne Lowe, Terri Van Gulik
Supporters:
The Ottawa Hospital: Inspired by research. Driven by compassion
The Ottawa Hospital is one of Canada’s largest learning and research hospitals with over 1,100 beds, approximately 12,000 staff and an annual budget of over $1.2 billion. Our focus on research and learning helps us develop new and innovative ways to treat patients and improve care. As a multi-campus hospital, affiliated with the University of Ottawa, we deliver specialized care to the Eastern Ontario region, but our techniques and research discoveries are adopted around the world. We engage the community at all levels to support our vision for better patient care. See www.ohri.ca for more information about research at The Ottawa Hospital.
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The University of Ottawa is home to over 50,000 students, faculty and staff, who live, work and study in both French and English. Our campus is a crossroads of cultures and ideas, where bold minds come together to inspire game-changing ideas. We are one of Canada’s top 10 research universities—our professors and researchers explore new approaches to today’s challenges. One of a handful of Canadian universities ranked among the top 200 in the world, we attract exceptional thinkers and welcome diverse perspectives from across the globe. www.uottawa.ca
Media Contact
Amelia Buchanan
Senior Communication Specialist
Ottawa Hospital Research Institute
Office: 613-798-5555 x 73687
Cell: 613-297-8315
ambuchanan@ohri.ca
