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Spirometry can’t catch all asthma diagnoses


January 4, 2023

“Undiagnosed asthma and other chronic respiratory diseases can be a daily struggle for patients. But with the right tools, we can easily diagnose and treat them.” - Dr. Shawn AaronA study led by Dr. Shawn Aaron suggests that asthma and eosinophilic bronchitis may be undiagnosed in a significant number of people who have symptoms, but have normal spirometry lung function tests. 

The findings published in the European Respiratory Journal were part of a study that used random digit dialing to find people across Canada who had never been diagnosed with a lung disease, but had unexplained shortness of breath, wheezing, increased mucus or chronic cough. If a participant’s spirometry lung function test was normal, they had further tests on the sensitivity of their airways. 

Of the 130 patients tested, 35% had hyperresponsive airways, a hallmark of asthma. In addition, 11% had eosinophilic bronchitis, an underdiagnosed form of bronchitis that can be treated with steroids. 

These findings suggest that while spirometry is a very useful tool, it misses some diagnoses, and additional tests are needed to give patients proper diagnoses and treatment.

“Undiagnosed asthma and other chronic respiratory diseases can be a daily struggle for patients. But with the right tools, we can easily diagnose and treat them.” - said Dr. Shawn Aaron, senior scientist and respirologist at The Ottawa Hospital and professor at the University of Ottawa.

Authors: Louis-Philippe Boulet, Marie-Ève Boulay, Andréanne Côté, J. Mark FitzGerald, Céline Bergeron, Catherine Lemière, M. Diane Lougheed, Katherine L. Vandemheen, Shawn D. Aaron

Core Resources: Ottawa Methods Centre

Funding: This study was funded by the Canadian Institute of Health Research. All research at The Ottawa Hospital is enabled by generous donors to The Ottawa Hospital Foundation.

 

Disease and research area tags: Asthma, Lung disease, Clinical trials

Scientific Program tags: Inflammation and Chronic Disease Program