The Ottawa Hospital Research Institute’s 24th annual Research Day was a great success!
Designed to highlight and celebrate the outstanding work of trainees and promote scientific interaction, the event featured 175 posters and 16 oral presentations.
There were special presentations from Dr. Janet Rossant, (Grimes keynote lecture), Yuan Tan (Worton Researcher in Training Award), Dr. Michael Verret (Grimshaw Researcher in Training Award) and Patrick Morris (patient speaker).
Prizes were awarded to the following students and postdoctoral fellows:
Oral Presentation Competition
1st: Alberto Camacho Magallanes (William Stanford group) Identification of TWIST1 as a true synthetic lethal target of TSC2-Null neural crest cells through genome-wide CRISPR knockout screen Co-authors: Eric Lian, Sean P. Delaney, Adam Pietrobon, Julien Yockell-Lelièvre, William L. Stanford
2nd: Nicholas Fabiano (Marco Solmi group) Adverse outcomes and mortality in individuals with eating disorder-related electrolyte abnormalities: a population-based cohort study in Ontario, Canada Co-authors: Nicholas Fabiano, Marco Solmi, Anna E. Clarke, Stephen G. Fung, Peter Tanuseputro, Greg Knoll, Daniel T Myran, Ann Bugeja, Manish M. Sood, Gregory L. Hundemer
3rd: Robert Myette (Dylan Burger group) Podocyte extracellular vesicle mitochondrial DNA as a novel marker in pediatric nephrotic syndrome Co-authors: Mayra Trentin Sonoda, Chet E. Holterman, George Cairns, Yan Burelle, Tyler T. Cooper, Gilles Lajoie, Christopher R.J. Kennedy, Dylan Burger
Clinical and applied health research award: Aidan Kirkham (Derek Roberts group) Effectiveness of implementation strategies to improve patient adherence to guideline-recommended cardiovascular medications for atherosclerotic occlusive disease: a systematic review and meta-analysis Co-authors: Jasmine Candeliere, Justin Presseau, Daniel I. McIsaac, Dean A. Fergusson, Derek J. Roberts
Postdoctoral and clinical fellow poster competition
1st: Sarah Nersesian (David Cook & Barbara Vanderhyden groups) HLA-mediated epitype-immune interactions in high-grade serous ovarian cancer Co-authors: John Abou-Hamad, Emma Durocher, Damian Carragher, Barbara Vanderhyden, David Cook
2nd: Ewa Henckel (Bernard Thébaud group) Optimizing lung biodistribution of umbilical cord derived MSCs in a multi-hit acute lung injury model in neonatal piglets: A pilot study Co-authors: Robert deKemp, Doreen Engelberts, Shumei Zhong, Arul Vadivel, Wojciech Durlak, Marc-Olivier Deguise, Daniel Freund, Maurio Rüdiger, Marius Möbius, Saas Khan, Ben Rotstein, Bernard Thébaud
3rd: Kazuhiro Okamoto (Benjamin Tsang group) Epigenetic signatures implicated in exosome-associated DNA could be a potential biomarkers predictive chemo-sensitivity in epithelial ovarian cancer Co-authors: Meshach Asare-Werehene, Dylan Burger, Arvin Zaker, Arvind Mer, Keiichiro Nakamura, Hisashi Masuyama, Benjamin Tsang
Clinical and applied health research award: Peter Greenstreet (Tim Ramsay group) A multi-arm multi-stage design for trials with no control arm and all pairwise testing Co-authors: Thomas Jaki, Alun Bedding, Pavel Mozgunov
PhD student poster competition
1st: Mahnaz Nazari (Bernard Thébaud group) Human induced pluripotent stem cell (hiPSC)-derived vasculogenic progenitor cells (VPCs) and their extracellular vesicles (EVs) ameliorate neonatal pulmonary hypertension Co-authors: Shumei Zhong, Arul Vadivel, Wojciech Durlak, Yupu Deng, David A Mann, Matthew George, Mervin Yoder, Dylan Burger, Duncan J. Stewart, Bernard Thébaud
2nd: Jaahnavi Dave (John Bell group) Using fluorescently conjugated viruses to identify barriers against oncolytic virotherapy Co-authors: Stephen Boulton, Siddharth Singh, Carolina Ilkow, John Bell
3rd: Wesley Chan (Antonio Colavita group) Asymmetric BAR-1/ß-catenin expression regulates neuron position during C. elegans ventral nerve cord assembly Co-authors: Justin Evans, Tony Roenspies, Elicia Preston, John Murray, Antonio Colavita
4th: Samuel Delisle (Luc Sabourin group) The relationship between Sox9 and drug resistance in HER2-positive breast cancer Co-authors: Luc Sabourin
Clinical and applied health research award: Alexa Keeshan (Curtis Cooper group) Obesity Does Not Reduce SARS-CoV-2 Humoral Vaccine Immunogenicity: A Stop the Spread Ottawa Analysis Co-authors: Mathieu D’Souza, Christopher A. Gravel, Marc-André Langlois, Curtis L. Cooper
Master’s student, medical students and residents poster competition
1st: Tamara Synek (Carolina Ilkow group) Investigating virally delivered prodrug therapies for targeted cancer cell treatment Co-authors: Monire Jamalkhah, Carolina Ilkow
2nd: George Akl (Robin Parks group) Exploring novel methods to express toxic proteins from oncolytic adenoviral vectors Co-authors: Kathy Poulin, Robin J. Parks
3rd: Prarthna Karunamurthy (Manoj Lalu group) Exploring the safety and efficacy of regulatory T cell derived extracellular vesicle therapy in a viral model of acute respiratory distress syndrome Co-authors: Julianne Morin, Brian Dorus, Zoe Fisk, Doreen Engelberts, Eva Kuhar, Forough Jahandideh, Manoj Lalu, Duncan Stewart
4th: Stephanie Lofaro (Michael Rudnicki group) Modulation of the EGFR signalling pathway through protein tyrosine phosphatase PTPN12 stimulates asymmetric division of dystrophin-deficient satellite stem cells Co-authors: Johnathan Smid, Michael Rudnicki
Clinical and applied health research award: Sarah Syed (Manish Sood group) Mental health services use by early career physicians compared to non-physicians: A gender-stratified population-based cohort study Co-authors: Samantha Yoo, Daniel T Myran, Maya Gibb, Marco Solmi, Ed Spilg, Daniel Kobewka, Claire Kendall, Natalie Fleming, Jerry Maniate, Greg Hundemer, Ian Colman, Peter Tanuseputro, Manish M Sood
Undergraduate poster competition
Isaac Glassman (Dylan Burger group) Predictive value of circulating extracellular vesicle levels for cardiovascular and mortality risk in hemodialysis patients Co-authors: Fengxia Xiao, Swapnil Hiremath, Marcel Ruzicka, Dylan Burger
People’s choice poster award
Emma Durocher (David Cook group) Cellular adaptation to cyclic chemotherapy treatment in high grade serous ovarian cancer models. Co-authors: John Abou-Hamad, Sarah Nersesian, David Cook
Poster competition honourable mention
Matthew Shen (Arya Rahgozar group) Explainable Artificial Intelligence to Diagnose Early Parkinson’s Disease via Voice Analysis Co-authors: Pouria Mortezaagha, Arya Rahgozar
Goodman Cohen summer student awards
1st: Roger Kou (Tzu-Fei Wang group) Anticoagulant Management of Patients with Cancer and Small Clots: A Retrospective Cohort Study Co-authors: Cameron Brown, Gabriella Hrubesz, Sarah Mckeague, Lauren Tokessy, Marc Carrier, Tzu-Fei Wang
2nd: Majd Al-Aarg (Rashmi Kothary group) Modelling Multiple Sclerosis Better: Unveiling the Cuprizone Autoimmune Encephalomyelitis Mouse Model Beyond the Brain Co-authors: Monique Marylin Alves de Almeida, Yves De Repentigny, Rashmi Kothary
Research Day Committee
Paul Albert (Co-Chair), Justin Presseau (Co-chair), Manoj Lalu, Rebecca Auer, Amelia Buchanan, Dylan Burger, Faith Izevbizua, Jaahnavi Dave, Chanèle Cyr Depauw, Jenn Ganton, Gregory Hundemer, Leah Labib, Ian Lorimer, Nathaniel Noblett, Tim Ramsay, Jing Wang, Jennifer Valentino
Volunteers: Nicol Lum, Lucy Sangani, Natasha Hollywood, Erin Hicke, Colleen Ford
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