Translational research grant could help to develop new immunotherapies for leukemia
April 5, 2021 - While CAR-T and other forms of immunotherapy are providing new hope for people with acute B-cell leukemia (B-ALL), much less progress has been made in treating acute T-cell leukemia (T-ALL). |
Researchers at The Ottawa Hospital awarded 17 CIHR grants worth $7.5 million
March 10, 2021 - Researchers at The Ottawa Hospital are playing a lead role in 17 new projects funded by the Canadian Institutes of Health Research (CIHR). |
Mysteries of cell fate unlocked with new measurement and modeling techniques
May 14, 2020 - Drs. Marjorie Brand, Ted Perkins and Jeffrey Ranish have found a missing link needed to fully understand how stem cells become specialized cells. |
How does a stem cell know what to be when it grows up?
October 22, 2019 - Dr. Marjorie Brand has been hooked on research ever since her training as a biochemistry student in France, where she discovered a new set of proteins that can turn genes on in the cell. This early success motivated the senior scientist at The ... |
Precision medicine approach for leukemia awarded $1.5M
May 1, 2019 - Acute myeloid leukemia (AML) is one of the deadliest forms of cancer. A team of researchers from The Ottawa Hospital and uOttawa is hoping to revolutionize treatment for AML by developing a “precision medicine” approach. |
Breakthrough reveals how a stem cell decides between two fates
March 29, 2019 - Dr. Marjorie Brand’s team discovered how a blood stem cell decides whether to become a red blood cell or a platelet-forming cell in a new study published in Cell Stem Cell. By using a technique that measures tiny amounts of proteins in individual ... |
Stem cell researchers tackle muscle weakness in older people
May 30, 2018 - For most people, muscle loss is a normal part of aging that makes daily tasks harder. Muscle loss called sarcopenia happens more quickly, leading to falls and decreased mobility. One reason for this muscle loss is that stem cells that help repair ... |
Exploiting the Achilles’ heel of a severe form of childhood leukemia
March 19, 2018 - Drs. Marjorie Brand and Jean-François Couture were awarded $588,000 from the Canadian Institutes of Health Research to investigate a new treatment approach for one of the most aggressive forms of childhood leukemia. The current treatment for T-cell |
The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate
January 30, 2018 - Sixteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $12.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a success r |
Pre-treated cells boost blood vessel repair
November 29, 2017 - Endothelial colony-forming cells (ECFCs) are stem-like cells found in umbilical cord blood that help repair damaged blood vessels. They may hold promise for the treatment of stroke, heart attack and blocked leg arteries. However, their rate of bloo |
Ottawa researchers find Achilles’ heel of a severe form of childhood leukemia
March 2, 2016 - Researchers at The Ottawa Hospital and the University of Ottawa have found the Achilles’ heel of one of the most aggressive forms of leukemia that affects both children and adults. They have also identified a possible new treatment that exploits |
$800,000 grant helps researchers find bone marrow cancer’s weak spots
January 20, 2016 - T cell acute lymphoblastic leukemia (T-ALL) is a rare, aggressive bone marrow cancer with a survival rate of 35 percent in adults and 70 percent in children. Currently the only treatment is intense and debilitating chemotherapy, with no other optio |
Dr. Jeffrey Dilworth awarded $2.3 million for muscle regeneration research
October 6, 2015 - Thousands of stem cells within our muscle tissue must make a difficult decision every day: Should I divide to produce another stem cell? Should I start becoming a new muscle fibre? Or should I just stay in bed? Dr. Jeffrey Dilworth was recently awa |
