Contact Information
TIAGO MESTRE, MSc MD
613798-5555 x 18986
tmestre@toh.ca
Clinical Administration:
Administrative Assistant
613-798-5555 X18986
Research Activities
• A randomized, placebo-controlled,
2-arm parallel-group superiority phase II study of GLYCOpyrrolate for moderate-to-severe sialorrhea in PARkinson’s disease - GLYCOPAR. ROLE: Principal Investigator (2014)
• Use of high resolution isotropic/three dimensional magnetic resonance imaging as a biomarker for the early distinction of Parkinson’s Disease from Atypical Parkinsonian Disorders. ROLE: Principal Investigator (2014)
• Lessebo effect in Parkinson’s disease. ROLE: Principal Investigator (2010 – current)
• Clinical significant changes in advanced Parkinson’s disease patients using the intravenous
levodopa model. ROLE: Principal Investigator (2010 – current)
• Intravenous levodopa as a means of assessing severity of dyskinesia and duration of wearing-off in Parkinson’s disease patients. Clinimetric properties of commonly used dyskinesia rating scales. ROLE: Co-Investigator. (2010 – current)
• Biomarkers of PD risk in LRRK2 mutation carriers. ROLE: Co-investigator (2012 – current)
• Biomarkers in Huntington’s Disease - Systematic review on the topic and definition of guidelines
for validation of biomarkers in Huntington’s disease. ROLE: Principal investigator (2012 –
current)