Publications
Selected Publications
1. Salloum Z, Dauner K, Li YF, Verma N, Valdivieso-González D, Almendro-Vedia VG, Zhang JD, Nakka K, Chen MX, McDonald JG, Corley CD, Sorisky A, Song BL, López-Montero I, Luo J, Dilworth JF, Zha X. “Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3.” Elife. 2024 Apr 11;13:e85964. doi: 10.7554/eLife.85964. Epub ahead of print.
2. Nakka K, Hachmer S, Mokhtari Z, Kovac R, Bandukwala H, Bernard C, Li Y, Xie G, Liu C, Fallahi M, Megeney LA, Gondin J, Chazaud B, Brand M, Zha X, Ge K, Dilworth FJ. “JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment”. Science. 2022 Aug 5;377(6606):666-669.
3. Singh RK, Haka AS, Bhardwaj P, Zha X and Maxfield FR, “Dynamic Actin Reorganization and Vav/Cdc42-dependent Actin Polymerization Promote Macrophage Aggregated LDL Uptake and Catabolism” Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB), 2019, Feb; 39(2): 137-149.
4. Courtney KC, Fung KYY, Maxfield FR, Fairn GD, Zha X, “Comment on “Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol.” ELife, 2018, Nov. 13; 7-10.
5. Courtney KC, Pezeshkian W, Raghupathy R, Zhang C, Darbyson A, Ipsen JH, Ford DA, Khandelia H, Presley JF, Zha X, “C24 Sphingolipids Govern the Transbilayer Asymmetry of Cholesterol and Lateral Organization of Model and Live-Cell Plasma Membranes.” Cell Reports, 2018 Jul 24;24(4):1037-1049.
6. Eid W, Dauner K, Courtney, Gagnon A, Parks R, Sorisky A, Zha X, “mTORC1 Activates SREBP-2 by Suppressing Cholesterol Trafficking to Lysosomes in Mammalian Cells”, Proc. Natl. Acad. Sci. 2017, Jul 25;114(30):7999-8004.
7. Dauner K, Eid W, Raghupathy R, Presley JF, Zha X, “mTOR complex 1 activity is required to maintain the canonical endocytic recycling pathway against lysosomal delivery”. J. Biol. Chem., 2017, April 7;292(14):5737-5747.
All Other Publications
Complete Publication List
1. Wang Y, Niimi M, Nishijima K, Waqar AB, Yu Y, Koike T, Kitajima S, Liu E, Inoue T, Kohashi M, Keyamura Y, Yoshikawa T, Zhang J, Ma L, Zha X, Watanabe T, Asada Y, Chen EY, Fan J. “Human apolipoprotein A-II protects against diet-Induced atherosclerosis in transgenic rabbits.” Arterioscler Thromb Vasc Biol. 2013;33(2):224-31.
2. L. Ma, F. Dong, M. Zaid, A. Kumar and X. Zha. “ABCA1 Enhances TLR4-Stimulated IL-10 Secretion through PKA Activation.” J. Biol. Chem., 2012, 23;287(48):40502-12
3. Q. C. Liu, X. Zha, H. Faralli, H. Yin, C. Louis-Jeune, E. Perdiguero, E. Pranckeviciene, P. Muñoz-Cànoves, M. A. Rudnicki, M. Brand, C. Perez-Iratxeta, and F. J. Dilworth. “Comparative expression profiling identifies differential roles for Myogenin and p38? MAPK signaling in myogenesis”, J. Mol. Cell Biol., 2012, 4(6):386-97.
4. X. Yu, X. Li, G. Zhao, J. Xiao, Z. Mo, K. Yin, Z. Jiang, Y. Fu, X. Zha, C. Tang. “OxLDL up-regulates Niemann-Pick type C1 expression through ERK1/2/COX-2/PPARα-signaling pathway in macrophages”, Acta Biochim Biophys Sin (Shanghai), 2012, 44(2):119-28.
5. J. Y. Lee, J. Karwatsky, L. Ma and X. Zha. “ABCA1 increases extracellular ATP to mediate cholesterol efflux to apoA-I”. American Journal of Physiology-cell physiology, 2011, 301, 101-109.
6. K. D. Hauff, R.W. Mitchell, F. Y. Xu, T. Dembinski, D. Mymin, X. Zha, P. C. Choy, G. M. Hatch. “Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1”. Lipids. 2011, 46, 795-804.
7. L. T. Ma, F. Dong, M. Denis, Y. Feng, M.D. Wang and X. Zha. “Ht31, a PKA anchoring inhibitor, induces robust cholesterol efflux and reverses macrophage foam cell formation through ABCA1”. J. Biol. Chem., 2011, 286, 3370-3378.
8. J. Karwatsky, L. T. Ma, F. Dong and X. Zha; “Cholesterol efflux to apoA-I in ABCA1-expressing cells is regulated by Ca2+ dependent-calcineurin signaling”. J. Lipid Research, 2010, 51:1144-56.
9. S. Nandi, L. Ma, M. Denis, J. Karwatsky, Z. Li and X. C. Jiang and X. Zha; “ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity”. J. Lipid Research 2009, 50, 456-466.
10. M. Denis, Y. D. Landry and X. Zha. “ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurs at the plasma membrane and not in the endocytic compartments.” J. Biol. Chem., 2008, 283, 16178-86.
11. Y. Landry, M. Denis, S. Nandi, S. Bell, A. M. Vaughan and X. Zha; “ABCA1 expression disrupts raft membrane microdomains through its ATPase fueled functions”. J. Biol. Chem., 2006, 281, 36091-101.
12. A. Ridsdale, M. Denis, P. Gougeon, J. K. Ngsee, J.F. Presley and X. Zha; “Cholesterol is required for efficient ER-Golgi transport of secretory membrane proteins”. Mol. Biol. Cell. 2006, 17, 1593-605.
PubMed Listings
