Aroldo Dargel

Contact Information

Aroldo Dargel, M.D., Ph.D.
613-798-5555
adargel@toh.ca

Contact ttanya@toh.ca for inquiries and meetings

Publications

Selected Publications


M. Nanda, D. Inkpen and A. Dargel, "Detecting Multiple Mental Health Disorders with Large Language Models," 2024 28th International Conference Information Visualisation (IV), Coimbra, Portugal, 2024, pp. 252-257, doi: 10.1109/IV64223.2024.00051.

Solmi M, Seitidis G, Mavridis D, Correll C, Dragioti E, Guimond S, Tuominen L, Dargél A, Carvalho AF, Fornaro M, Maes M, Ferrari A, Monaco F, Song M, Il Shin J, Cortese S. Incidence, prevalence, and global burden of schizophrenia – data, with critical appraisal, from the Global Burden of Disease (GBD) 2019. Mol Psychiatry. 2023. doi: 10.1038/s41380-023-02138-4

Dargél, A. A., Mosconi, E., Masson, M., Plaze, M., Taieb, F., Von Platen, C., Buivan, T. P., Pouleriguen, G., Sanchez, M., Fournier, S., Lledo, P., & Henry, C. (2020). Toi meme, a mobile health platform for measuring bipolar illness activity: Protocol for a feasibility study. JMIR Research Protocols, 9(8), e18818. https://doi.org/10.2196/18818

Dargél, A. A., Volant, S., Brietzke, E., Etain, B., Olié, E., Azorin, J., Gard, S., Bellivier, F., Bougerol, T., Kahn, J., Roux, P., Aubin, V., Courtet, P., Leboyer, M., & Henry, C. (2020). Allostatic load, emotional hyper-reactivity, and functioning in individuals with bipolar disorder. Bipolar Disorders, 22(7), 711-721. https://doi.org/10.1111/bdi.12927

Dargél, A. A., Roussel F, Volant S, Etain B, Grant R, Azorin JM, M'Bailara K, Bellivier F, Bougerol T, Kahn JP, Roux P, Aubin V, Courtet P, Leboyer M; FACE-BD Collaborators, Kapczinski F, Henry C. Emotional hyper-reactivity and cardiometabolic risk in remitted bipolar patients: a machine learning approach. Acta Psychiatr Scand. 2018; 138 (4): 348-359. doi: 10.1111/acps.12901. 




All Other Publications


Dargél AA.
Beyond evidence and toward long-term and individualized management of bipolar disorder in real-world practice. Bipolar Disord. 2021 ; 23 (5): 511-512. doi: 10.1111/bdi.13072. 

Dargél AA. Which Sounds Better: Analog or Digital Psychiatry? Bipolar Disord. 2020; 22 (8): 785- 787. doi: 10.1111/bdi.13003. 

Dargél AA., Volant S, Karim E., Mosconi E. Adjunctive family psychoeducation on patients and family outcomes in real-world bipolar disorder clinical practice. Bipolar Disord. 2020; 22 (S1): 57- 59. doi: 10.1111/bdi.12937. 

Henry C, Bigot M, Alonso M, Lledo PM, Dargél AA. Can olfactory dysfunction be a marker of trait or states of bipolar disorders? A comprehensive review. J Affective Disorders. 2020; 266: 498- 502. doi: 10.1016/j.jad.2020.01.081. 

Dargél AA. Chronic mood instability, cardiometabolic risk and functional impairment in bipolar patients: the clinical relevance of a multidimensional approach. Bipolar Disord. 2019; 21 (Suppl. 1): 52-53. doi: 10.1111/bdi.12744 

Dargél AA, Volant S, Saha S, Etain B, Grant R, Azorin JM, Gard S, Bellivier F, Bougerol T, Roux P, Aubin V, Courtet P, Leboyer M; FACE-BD collaborators, Scott J, Henry C. Activation Levels, Cardiovascular Risk, and Functional Impairment in Remitted Bipolar Patients: Clinical Relevance of a Dimensional Approach. Psychother Psychosom. 2019; 88 (1): 45-47. doi: 10.1159/000493690. 

Kauer-Sant'Anna M, Frey BN, Fijtman A, Loredo-Souza AC, Dargél AA, Pfaffenseller B, Wollenhaupt-Aguiar B, Gazalle FK, Colpo GD, Passos IC, Bücker J, Kunz M, Pinho M, Kapczinski NS, Goi PD, Magalhães PV, Reckziegel R, Burque RK, de Azevedo Cardoso T, Kapczinski F. Adjunctive tianeptine treatment for bipolar disorder: A 24-week randomized, placebo-controlled, maintenance trial. J Psychopharmacol. 2019; 33 (4): 502-510. doi: 10.1177/0269881119826602.   

Dargél AA, Roussel F, Volant S, Etain B, Grant R, Azorin JM, M'Bailara K, Bellivier F, Bougerol T, Kahn JP, Roux P, Aubin V, Courtet P, Leboyer M; FACE-BD Collaborators, Kapczinski F, Henry C. Emotional hyper-reactivity and cardiometabolic risk in remitted bipolar patients: a machine learning approach. Acta Psychiatr Scand. 2018; 138 (4): 348-359. doi: 10.1111/acps.12901. 

Abib RT, Gaman A, Dargél AA, Tamouza R, Kapczinski F, Gottfried C, Leboyer M. Intracellular Pathogen Infections and Immune Response in Autism. Neuroimmunomodulation. 2018; 25 (5- 6): 271-279. doi: 10.1159/000491821. 

Henry C, Dargél AA. What can we learn about mood disorders from olfactory processes? Bipolar Disord. 2018; 20 (6): 562-563. doi: 10.1111/bdi.12660. 

Dargél AA, Masson M. Bipolar disorder: a single illness. Bipolar Disord. 2018; 20 (5): 492-493. doi: 10.1111/bdi.12651. 

Richa S, Chammay R, Dargél A, Henry C, Masson M. Ethical considerations in bipolar disorders. Encephale. 2018; 44 (3): 286-287. doi: 10.1016/j.encep.2017.12.005.

Dargél AA, Godin O, Etain B., Hirakata V, Azorin JM, M'Bailara, Bellivier F, Leboyer M, Henry C. Emotional reactivity, functioning, and C-reactive protein alterations in remitted bipolar patients: clinical relevance of a dimensional approach. Aust N Zeal J Psychiatry. 2017; 51 (8): 788-798. doi: 10.1177/0004867417691850. 

Dargél AA, Masson M and Henry C. The RANZCP guidelines: Managing mood disorders in the real world. Aust N Zeal J Psychiatry. 2016; 50 (12): 1198-1199. doi: 10.1177/0004867416676373. 

Dargél AA, Godin O, kapczinski F, Kupfer D, Leboyer M. C-reactive protein alterations in bipolar disorder: a meta-analysis. J Clin Psychiatry. 2015;76(2):142-50. doi:10.4088/JCP.14r09007. 

Henry C, Etain C, Godin O, Dargél AA, Azorin JM, Gard S, Bellivier F, Bougerol T, Kahn1 JP, Passerieux C, Aubin V, Courtet P, Leboyer M. Bipolar patients referred to specialized services of care: not resistant but impaired by subsyndromal symptoms: results from FACE-BD cohort. Aust N Z J Psychiatry. 2015;49(10):898-905. doi: 10.1177/0004867415585582. 

Etain B, Lajnef M, Henrion A, Dargél AA, Stertz S, Kapczinski F, Mathieu F, Henry C, Gard S, Khan JP, Leboyer M, Bellivier F. Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders. Sci Rep. 2015; 5:16301. doi: 10.1038/srep16301. 

Fond G, Hamdani N, Kapczinski F, Boukouaci W, Drancourt N, Dargél A, Oliveira J, Le Guen E, Marlinge E, Tamouza R, Leboyer M. Effectiveness and tolerance of anti-inflammatory drugs’ add- on therapy in major mental disorders: a systematic qualitative review. Acta Psychiatr Scand. 2014; 129:163-179. doi: 10.1111/acps.12211. 

Fond G, Loundou A, Hamdani N, Boukouaci W, Dargél A, Roger M, Tamouza R, Leboyer M, Boyer L. Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis. Eur Arch Psychiatry Clin Neurosci. 2014; 264(8):651-660. doi: 10.1007/s00406- 014-0502-z. 

Fond G, Loundou A, Hamdani N, Boukaci W, Dargél A, Roger M, Tamouza R, Leboyer M, Boyer L. The “psychomicrobiotic”: Targeting microbiota in major psychiatric disorders: a systematic review. Pathologie Biologie. 2015; 63(1):35-42. doi: 10.1016/j.patbio.2014.10.003. 

Oliveira J, Busson M, Etain B, Jamain S, Dargél AA, Hamdani N, Leboyer M, Tamouza R. Polymorphism of Toll-like receptor 4 gene in bipolar disorder. J Affective Disorders. 2014; 152- 154:395-402. doi: 10.1016/j.jad.2013.09.043. 

Fries GR, Pfaffenseller B, Stertz L, Paz AV, Dargél AA, Kunz M, Kapczinski F. Staging and Neuroprogression in Bipolar Disorder. Curr Psychiatry Reports. 2012; 14:667-75; doi: 10.1007/s11920-012-0319-2. 

Thomé E, Dargél AA, Migliavaca FM, Kapczinski F, Cereser KM. Stigma experiences in bipolar patients: the impact upon overall and specific areas of functioning. J Psychiatric Mental Health Nurs. 2011; Nov 17:1-7. doi: 10.1111/j.1365-2850.2011.01849.x. 

Vasconcelos-Moreno MP, Dargél AA, Goi PD, Bragatti JA, Kapczinski F, Kauer-Sant’Anna M. Effect of mood stabilizers on improvement of behavioural and manic-like symptoms secondary to herpes simplex encephalitis: a case report. Int J Neuropsychopharmacology. 2011; 14:718-20. doi:10.1017/S1461145710001598. 

Spanemberg L, Noguera E, Da Silva CTB, Dargél AA, Menezes FS, Cataldo A et al. High prevalence and prescription of benzodiazepines for elderly. Gen Hosp Psychiatry. 2011; Jan-Feb;33(1):45- 50. doi: 10.1016/j.genhosppsych.2010.12.004. 

Klock C, Cerski M, Dargél A, Goldani LZ. Case Report. Disseminated aspergillosis complicating pregnancy. Mycoses. 2002 Nov;45(9-10):408-10. Goldani LZ, Aquino VR, Dargél AA. Disseminated cutaneous sporotrichosis in an AIDS patient receiving maintenance therapy with fluconazole for previous cryptococcal meningitis. Clin Infect Dis. 1999 Jun;28(6):1337-8.