Antoine Hakim profile picture

Contact Information

Antoine Hakim, O.C., MD, PhD, FRCPC
613-562-5462
ahakim@ohri.ca

Nancy MacDonald Executive Assistant nmacdonald@ohri.ca

PLEASE NOTE:
Dr. Hakim is currently NOT taking on any graduate students, Research Fellows or Research Associates.

Publications

Selected Publications

Life-time Summary: 158 peer-reviewed articles; 26 other publications

  1. Book: A. Hakim, Save Your Mind: Seven Rules to Avoid Dementia. Published by Barlow Books, April 2017.
  2. Ganesh A, Lindsay P, Fang J, Kapral, Côté R, Joiner I, Hakim A, Hill M. Integrated systems of stroke care and reduction in 30-day mortality: A retrospective analysis. Neurology 2016;86:1–7.
  3. Book: A. Hakim, Préservez votre vitalité mentale: 7 Règles Pour Prévenir La Démence. Published by Les Editions de L’Homme. June 2016.
  4. Edrissi H, Schock SC, Hakim A, Thompson CS. Microparticles generated during chronic cerebral ischemia increases the permeability of microvascular endothelial barriers in vitro. Brain Res. 2016;1634, 83-93.
  5. Schock S, Edrissi H, Burger D, Cadonic R, Hakim A, Thompson C. Microparticles generated during chronic cerebral ischemia deliver proapoptotic signals to cultured endothelial cells. Biochem Biophys Res Commun. 2014 Jul 18;450(1):912-7**
  6. Hakim A. Silent, but preventable, perils. Nature. 2014 Jun 25;510(7506):S12.*
  7. Román GC, Hakim A. rt-PA in acute stroke patients with history of cognitive impairment: Do not hesitate to treat. Neurology. 2014;82(23):2044-5.*
  8. Winocur G, Thompson C, Hakim A, Greenwood C. The effects of high- and low-risk environments on cognitive function in rats following 2-vessel occlusion of the carotid arteries: A behavioral study. Behavioural Brain Research. 2013; 252: 144-156.**
  9. Dirnagl U, Hakim A, Macleod M, Fisher M, Allan S, Steinberg G, Planas A, Savitz S, Iadecola C, Meairs S.. A concerted appeal for international cooperation in preclinical stroke research. Stroke. 2013; 44:1754-1760.*
  10. Willis K, Hakim A. "Emerging Approaches to Modifying Risk and Delaying Onset of Dementia: Stroke Prevention and Cognitive Reserve. Front. Neurol., 21 March 2013 | doi: 10.3389/fneur.2013.00013e*
 

 


All Other Publications

  1. Hakim J, Senterman M, Hakim A. Preeclampsia Is A Biomarker For Vascular Disease In Both Mother & Child. The Need For A Medical Alert System. International Journal of Pediatrics. 2013; Article ID953150, 8 pages.*
  2. Ng J, Turek M, Hakim A. "Heart disease as a risk factor for dementia. Clinical Epidemiology,2013; 5, 135-145.
  3. Burger D, Schock S, Thompson C, Montezano A, Hakim A, Touyz R. Microparticles: Biomarkers and Beyond. Clinical Science, 2013; 124, 423-441.**
  4. Hakim AM. The Future of Stroke Thrombolysis. Ann N Y Acad Sci. 2012 Sep;1268(1):8-13.*Hakim AM. Depression, Strokes and Dementia: New Insights into an Unfortunate Pathway. Cardiovascular Psychiatry and Neurology Journal. 2011-published.*
  5. Juma WM, Lira A, Marzuk A, Marzuk Z, Hakim A, Thompson C. C-reactive protein expression in a rodent model of chronic cerebral hypoperfusion. Brain Res, 2011;1414, 85-93.** 
  6. Sharma M, Hakim A. The Management of Hypertension for Primary Stroke Prevention: A proposed Approach. Int J Stroke. 2011 Apr;6(2):144-9.*
  7. Lindsay MP, Culebras A, Hacke W, Jowi J, Lalor E, Mehndiratta MM, Norrving B, Wong L, Hakim AM. Development and implementation of stroke guidelines: the WSO Guidelines Subcommittee takes the first step (Part one of a two-part series on the work of the WSO Stroke Guidelines Subcommittee). Int J Stroke. 2011 Apr;6(2):155-8.***
  8. Endres M, Heuschmann PU, Laufs U, Hakim AM. Primary prevention of stroke: blood pressure, lipids, and heart failure. Eur Heart J. 2011 Mar;32(5):545-52.**Endres M, Heuschmann PU, Laufs U, Hakim A. Frontiers in cardiovascular medicine “Primary prevention of stroke: Blood pressure, lipids and heart failure”. Invited Comprehensive Clinical Review Article for the European Heart Journal (EHJ). Published February 11, 2011.*
  9. Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M, Buchan AM, Lo EH, Skolnick BE, Furie KL, Hankey GJ, Kivipelto M, Morris J, Rothwell PM, Sacco RL, Smith SC Jr, Wang Y, Bryer A, Ford GA, Iadecola C, Martins SC, Saver J, Skvortsova V, Bayley M, Bednar MM, Duncan P, Enney L, Finklestein S, Jones TA, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg MP, Heiss WD, Saarelma O, Schwamm LH, Shinohara Y, Trivedi B, Wahlgren N, Wong LK, Hakim A, Norrving B, Prudhomme S, Bornstein NM, Davis SM, Goldstein LB, Leys D, Tuomilehto J., Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, and St. Joseph's Healthcare London, London, Ont., USA.. Stroke: Working toward a Prioritized World Agenda. Cerebrovasc Dis. 2010 May 24;30(2):127-147.**Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M, Buchan AM, Lo EH, Skolnick BE, Furie KL, Hankey GJ, Kivipelto M, Morris J, Rothwell PM, Sacco RL, Smith SC Jr, Wang Y, Bryer A, Ford GA, Iadecola C, Martins SC, Saver J, Skvortsova V, Bayley M, Bednar MM, Duncan P, Enney L, Finklestein S, Jones TA, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg MP, Heiss WD, Saarelma O, Schwamm LH, Shinohara Y, Trivedi B, Wahlgren N, Wong LK, Hakim AM, Norrving B, Prudhomme S, Bornstein NM, Davis SM, Goldstein LB, Leys D, Tuomilehto J. troke: Working toward a Prioritized World Agenda. Stroke. 2010 Jun;41(6):1084-99. Review** 
  10. Saposnik G, Black S, Hakim A, Fang J, Tu J and Kapral M. Age disparities in Stroke Quality of Care and Delivery of Health Services. Stroke. 2009 Oct;40(10):3328-35.**
  11. Dowlatshahi D, Hakim A, Fang J, Sharma M. Pre-admission antithrombotics are associated with improved outcomes following ischemic stroke: a cohort from the Registry of the Canadian Stroke Network. International Journal of Stroke, October 2009,4: 328–334.**
  12. Charron C, Schock S, Proulx G, Thompson C, Hakim A, Plamondon H. Protection conferred by Corticotropin-releasing hormone in rat primary cortical neurons against chemical ischemia involves opioid receptor activation. Brain Research.2009 Feb 27 1257: 117-127.**
  13. Thompson C and Hakim A. Living Beyond Our Physiological Means: Small Vessel Disease Of The Brain Is An Expression Of A Systemic Failure In Arteriolar Function. A Unifying Hypothesis. Stroke 2009 May; 40 (5): E 322-30.*

PubMed Listings

For more publications use this PubMed ID link.