1. Robert L. Myette, Fengxia Xiao, Pavel Geier1, Janusz Feber1, Dylan Burger and Christopher R. J. Kennedy. Urinary podocyte-derived large extracellular vesicles are increased in paediatric idiopathic nephrotic syndrome. Nephrol Dial & Transplantation. 2023; 38, 2089-91.

2. Jha, J.C., Dai, A., Garzarella, J., Charlton, A., Urner, S., Østergaard, J.A., Okabe, J., Holterman, C.E., Skene, A., Power, D.A., Ekinci, E.I.,Coughlan, M.T., Schmidt, H. H.W., Cooper, M.E., Touyz, R.M., Kennedy, C.R.J., Jandeleit-Dahm, K. Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways. Diabetes 2022; 71, 1282–1298.

3. Holterman CE, Boisvert NC, Thibodeau JF, Kamto E, Novakovic M, Abdelrahman K, Ferguson S, Kennedy CRJ. Podocyte NADPH Oxidase 5 promotes renal inflammation regulated by the toll-like receptor pathway. Antioxid Redox Signal. 2019;30(15):1817-1830.

4. Holterman CE, Boisvert NC, Thibodeau J-F, Kamto E, Novakovic M, Abdelrahman K, Ferguson S, Kennedy CRJ. Podocyte NADPH Oxidase 5 promotes renal inflammation regulated by the toll-like receptor pathway. Antioxid Redox Signal. 2018;doi.org/10.1089/ars.2017.7402.

5. Boisvert NC, Holterman CE, Gutsol A, Coulombe J, Pan W, Alexander RT, Gray DA, Kennedy CRJ. Ubiquitin COOH-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis. Am J Physiol Physiol. 2018;315(2):f353-363.

6. Boisvert NC, Holterman CE, Thibodeau J-F, Nasrallah R, Kamto E, Comin CH, da F. Costa L, Carter A, Hébert RL, Gutsol A, Cron GO, Lacoste B, Gray DA, Kennedy CRJ. Hyperfiltration in Ubiquitin C-terminal hydrolase L1 -deleted mice. Clin Sci. 2018;132:1453-1470.

7. Boisvert NC, Holterman CE, Gutsol A, Coulombe J, Pan W, Alexander RT, Gray DA, Kennedy CRJ. Ubiquitin C-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis. Am J Physiol Physiol. 2018;315(2):F353-F363. http://www.ncbi.nlm.nih.gov/pubmed/29667913

8. Thibodeau JF, Holterman CE, He Y, Carter A, Cron GO, Boisvert NC, Abd-Elrahman KS, Hsu KJ, Ferguson SS, Kennedy CRJ. Vascular smooth muscle-specific EP4 receptor deletion in mice exacerbates angiotensin II-induced renal injury. Antioxid Redox Signal. 2016;25(12):642-656.

9. Burger D, Thibodeau JF, Holterman CE, Burns KD, Touyz RM, Kennedy CRJ. Urinary podocyte microparticles identify prealbuminuric diabetic glomerular injury. J Am Soc Nephrol. 2014;25(7): 1401-1407.

10. Holterman CE, Thibodeau JF, Towaij C, Gutsol A, Montezano AC, Parks RJ, Cooper ME, Touyz RM, Kennedy CRJ. Nephropathy and elevated BP in mice with podocyte-specific NADPH oxidase 5 expression. J Am Soc Nephrol. 2014;25(4):784-797.

11. Read NC, Gutsol A, Holterman CE, Carter A, Coulombe J, Gray DA, Kennedy CRJ. Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis. Biochim Biophys Acta. 2014;1842(7):1028-1040.

12. Thibodeau JF, Holterman CE, Burger D, Read NC, Reudelhuber TL, Kennedy CRJ. A novel mouse model of advanced diabetic kidney disease. PLoS One. 2014;9(12):e113459.

13. Thibodeau JF, Nasrallah R, Carter A, He Y, Touyz RM, Hébert RL, Kennedy CRJ. PTGER1 Deletion Attenuates Renal Injury in Diabetic Mouse Models. Am J Pathol. 2013;183(6):1789-802.

14. Stitt-Cavanagh EM, Faour WH, Takami K, Carter A, Vanderhyden B, Guan Y, Schneider A, Breyer MD, Kennedy CRJ. A maladaptive role for EP4 receptors in podocytes. J Am Soc Nephrol. 2010; 21(10):1678-90.

All Other Publications

1. Robert L. Myette, Fengxia Xiao, Pavel Geier1, Janusz Feber1, Dylan Burger and Christopher R. J. Kennedy. Urinary podocyte-derived large extracellular vesicles are increased in paediatric idiopathic nephrotic syndrome. Nephrol Dial & Transplantation. 2023; 38, 2089-91.
2. Jha, J.C., Dai, A., Garzarella, J., Charlton, A., Urner, S., Østergaard, J.A., Okabe, J., Holterman, C.E., Skene, A., Power, D.A., Ekinci, E.I.,Coughlan, M.T., Schmidt, H. H.W., Cooper, M.E., Touyz, R.M., Kennedy, C.R.J., Jandeleit-Dahm, K. Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways. Diabetes 2022; 71, 1282–1298.
3. Holterman, C.E., Myette, R., Burger, D and Kennedy, C.R.J.. A letter to the editor about “dopamine 1 receptor activation protects mouse diabetic podocytes injury via regulating the PKA/NOX-5/p38 MAPK axis”. Experimental Cell Research 2022; 415 113065
4. Gutsol, A.A., Blanco P., Hale, T.M., Thibodeau, J-F., Holterman, C.E., Nasrallah, R., Correa, J.W.N., Alanasiev, S.A., Touyz, R.M., Kennedy, C.R.J., Burger, D., Hébert, R.L., Burns, K.D. Comparative analysis of hypertensive nephrosclerosis in animal models of hypertension and its relevance to human pathology Glomerulopathy. PLOS ONE 2022: https://doi.org/10.1371/journal.pone.0264136.
5. Burger, Dylan, Abdelrasoul, Amira; Alexander, R. Todd; Ballermann, Barbara; Bridgewater, Darren;Chan, John S. D; Cunanan, Joanna; Cybulsky, Andrey V; Gerarduzzi, Casimiroi; Gunaratnam, Lakshman; Hartwig, Sunny; Kapus, Andras; Kennedy, Christopher R. J; Lamarche, Caroline; Myette, Robert L; Nmecha, Ifeanyi Kennedy; Stalker, Leanne; Szaszi, Katalin; Torban, Elena; Zhang, Shao Ling; Takano, Tomoko. Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit. Canadian Journal of Kidney Health and Disease 2022; DOI 10.1177/20543581221144824.
6. Deliyanti D, Alrashdi SF, Touyz RM, Kennedy CRJ, Jha JC, Cooper ME, Jandeleit-Dahm KA, Wilkinson-Berka JL. NOX1, NOX4 and NOX5, promote vascular permeability and neovascularization in retinopathy. Hypertension 2020;75(4):1091-1101.
7. Bouzakri K, Veyrat-Durebex C, Holterman C, Arous C, Barbieux C, Bosco D, Altirriba J, Alibashe M, Tournier BB, Gunton JE, Mouche S, Bietiger W, Forterre A, Berney T, Pinget M, Christofori G, Kennedy CRJ, Szanto I. Beta-cell-specific expression of nicotinamide adenine dinucleotide phosphate oxidase aggravates high fat diet induced impairment of islet insulin secretion in mice. Antioxidants and Redox Signaling 2020; 32(9):618-635.
8. Ouellette J, Toussay X, Comin CH, da Costa LF, Ho M, Lacalle-Aurioles M, Freitas-Andrade M, Yan Liu QY, Leclerc S, Pan Y, Liu Z, Thibodeau JF, Yin M, Carrier M, Morse CJ, Van Dyken P, Bergin CJ, Baillet S, Kennedy CRJ, Tremblay ME, Benoit YD, Stanford WL, Burger D, Stewart DJ, Lacoste B. Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice. Nature Neuroscience. 2020;23(9):1090-1101.
9. Simard JC, Thibodeau JF, Leduc M, Tremblay M, Laverdure A, Sarra-Bournet F, Gagnon W, Ouboudinar J, Gervais L, Felton A, Letourneau S, Geerts L, Cloutier MP, Hince K, Corpuz R, Blais A, Quintela VM, Duceppe JS, Abbott SD, Blais A, Zacharie B, Laurin P, Laplante SR, Kennedy CRJ, Hébert RL, Leblond FA, Grouix B, Gagnon L. Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease. Scientific Reports. 2020;(10):12778.
10. Nasrallah R, Zimpelmann J, Robertson SJ, Ghossein J, Thibodeau JF, Kennedy CRJ, Gutsol A, Xiao F, Burger D, Burns KD, Hébert RL. Prostaglandin E2 receptor EP1 (PGE2/EP1) deletion promotes glomerular podocyte and endothelial cell injury in hypertensive TTRhRen mice. Lab Invest. 2019; Sep 16. doi: 10.1038/s41374-019-0317-7.
11. Thibodeau JF, Simard JC, Holterman CE, Blais A, Cloutier MP, Medeiros T, Leduc M, Grouix B, Leblond FA, Burger D, Hébert RL, Kennedy CRJ, Gagnon L. PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice. Clin Sci (Lond). 2019;133(14):1587-1602.
12. Gutsol A, Blanco P, Samokhina S, Afanasiev S, Kennedy CRJ, Popov S and Burns KD. A novel method for comparison of arterial remodeling in hypertension: Quantification of arterial trees and recognition of remodeling patterns on histological sections. PLoS One. 2019;14(5):e0216734.
13. Tutunea-Fatan E, Abd-Elrahman KS, Thibodeau JF, Holterman CE, Holleran BJ, Leduc R, Kennedy CRJ, Gros R, Ferguson SSG. GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation. Sci Rep. 2018;8(1):11415.
14. Gagnon L, Leduc M, Thibodeau JF, Zhang M, Grouix B, Sarra-Bournet F, Gagnon W, Hince K, Tremblay M, Geerts L, Kennedy CRJ, Hébert RL, Gutsol A, Holterman C, Kamto E, Gervais L, Ouboudinar J, Richard J, Felton A, Laverdure A, Simard J, Létourneau S, Cloutier M, Leblond F, Abbott S, Penney C, Duceppe J, Zacharie B, Dupuis J, Calderone A, Nguyen Q, Harris R, Laurin P. A Newly discovered antifibrotic pathway regulated by two fatty acid receptors: GPR40 and GPR84. Am J Pathol. 2018;188(5):1132-48.
15. Holterman CE, Boisvert NC, Thibodeau JF, Kamto E, Novakovic M, Abdelrahman K, Ferguson S, Kennedy CRJ. Podocyte NADPH Oxidase 5 promotes renal inflammation regulated by the toll-like receptor pathway. Antioxid Redox Signal. 2019;30(15):1817-1830.
16. Yee A, Papillon J, Guillemette J, Kaufman DR, Kennedy CRJ, Cybulsky A V. Proteostasis as a therapeutic target in glomerular injury associated with mutant α-actinin-4. Am J Physiol Physiol. 2018;315:F954-F966.
17. Jha JC, Dai A, Holterman CE, Cooper ME, Touyz RM, Kennedy CRJ, Jandeleit-Dahm KAM. Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse. Diabetologia. 2019;62(9):1712-1726.
18. Holterman CE, Boisvert NC, Thibodeau J-F, Kamto E, Novakovic M, Abdelrahman K, Ferguson S, Kennedy CRJ. Podocyte NADPH Oxidase 5 promotes renal inflammation regulated by the toll-like receptor pathway. Antioxid Redox Signal. 2018;doi.org/10.1089/ars.2017.7402.
19. Boisvert NC, Holterman CE, Gutsol A, Coulombe J, Pan W, Alexander RT, Gray DA, Kennedy CRJ. Ubiquitin COOH-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis. Am J Physiol Physiol. 2018;315(2):f353-363.
20. Yee A, Papillon J, Guillemette J, Kaufman DR, Kennedy CRJ, Cybulsky AV. Proteostasis as a therapeutic target in glomerular injury associated with mutant α-actinin-4. Am J Physiol Physiol. 2018;315(4):f954-966.
21. Montezano AC, Camargo LDL, Persson P, Rios FJ, Harvey AP, Anagnostopoulou A, Palacios R, Gandara ACP, Alves-Lopes R, Neves KB, Dulak-Lis M, Holterman CE, de Oliveira PL, Graham D, Kennedy CRJ, Touyz RM. NADPH Oxidase 5 Is a pro-contractile nox isoform and a point of cross-talk for calcium and redox signaling-implications in vascular function. J Am Heart Assoc. 2018;7:e009388.
22. Boisvert NC, Holterman CE, Thibodeau J-F, Nasrallah R, Kamto E, Comin CH, da F. Costa L, Carter A, Hébert RL, Gutsol A, Cron GO, Lacoste B, Gray DA, Kennedy CRJ. Hyperfiltration in Ubiquitin C-terminal hydrolase L1 -deleted mice. Clin Sci. 2018;132:1453-1470.
23. Munkonda MN, Akbari S, Landry C, Sun S, Xiao F, Turner M, Holterman CE, Nasrallah R, Hébert RL, Kennedy CRJ, Burger D. Podocyte-derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36. J Extracell Vesicles. 2018;7(1):1432206.
24. Boisvert NC, Holterman CE, Gutsol A, Coulombe J, Pan W, Alexander RT, Gray DA, Kennedy CRJ. Ubiquitin C-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis. Am J Physiol Physiol. 2018;315(2):F353-F363. http://www.ncbi.nlm.nih.gov/pubmed/29667913
25. Nasrallah R, Zimpelmann J, Eckert D, Ghossein J, Geddes S, Beique J-C, Thibodeau JF, Kennedy CRJ, Burns KD, Hébert RL. PGE 2 EP 1 receptor inhibits vasopressin-dependent water reabsorption and sodium transport in mouse collecting duct. Lab Investig. 2018;98(3):360-370.
26. Abdallah MS, Kennedy CRJ, Stephan JS, Khalil PA, Mroueh M, Eid AA, Faour WH. Transforming growth factor-β1 and phosphatases modulate COX-2 protein expression and TAU phosphorylation in cultured immortalized podocytes. Inflamm Res. 2018;67(2):191-201.
27. Jha JC, Banal C, Okabe J, Gray SP, Hettige T, Chow BSM, Thallas-Bonke V, De Vos L, Holterman CE, Coughlan MT, Power DA, Skene A, Ekinci EI, Cooper ME, Touyz RM, Kennedy CRJ, Jandeleit-Dahm K. NADPH Oxidase Nox5 accelerates renal injury in diabetic nephropathy. Diabetes. 2017; 66(10):2691-2703.
28. Lytvyn Y, Xiao F, Kennedy CRJ, Perkins BA, Reich HN, Scholey JW, Cherney DZ, Burger D. Assessment of urinary microparticles in normotensive patients with type 1 diabetes. Diabetologia. 2017; 60(3):581-584.

29. Thibodeau JF, Holterman CE, He Y, Carter A, Cron GO, Boisvert NC, Abd-Elrahman KS, Hsu KJ, Ferguson SS, Kennedy CRJ. Vascular smooth muscle-specific EP4 receptor deletion in mice exacerbates angiotensin II-induced renal injury. Antioxid Redox Signal. 2016;25(12):642-656.
30. Xiao F, Zimpelmann J, Burger D, Kennedy CRJ, Hébert RL, Burns KD. Protein kinase C-δ mediates shedding of angiotensin-converting enzyme 2 from proximal tubular cells. Front Pharmacol. 2016;7:146.
31. Holterman CE, Read N, Kennedy CRJ. Nox and renal disease. Clinical Science. 2015;128(8):465-481.
32. Holterman CE, Thibodeau JF, Kennedy CRJ. NADPH oxidase 5 and renal disease. Curr Opin Nephrol Hypertens. 2015;24(1):81-87.
33. Kennedy CRJ. Changing and challenging times for Canadian kidney health and disease research. Can J Kidney Health Dis. 2015;2(1):49.
34. Kennedy CRJ. Nitrate, nitrite, and nitric oxide find a home in the kidney by offsetting angiotensin ii-mediated hypertension. Hypertension. 2015;65(1):31-33.
35. Nasrallah R, Hassouneh R, Zimpelmann J, Karam AJ, Thibodeau JF, Burger D, Burns KD, Kennedy CRJ, Hébert RL. Prostaglandin E2 increases proximal tubule fluid reabsorption, and modulates cultured proximal tubule cell responses via EP1 and EP4 receptors. Lab Invest. 2015;95(9):1044-55.
36. Burger D, Thibodeau JF, Holterman CE, Burns KD, Touyz RM, Kennedy CRJ. Urinary podocyte microparticles identify prealbuminuric diabetic glomerular injury. J Am Soc Nephrol. 2014;25(7): 1401-1407.
37. Holterman CE, Thibodeau JF, Towaij C, Gutsol A, Montezano AC, Parks RJ, Cooper ME, Touyz RM, Kennedy CRJ. Nephropathy and elevated BP in mice with podocyte-specific NADPH oxidase 5 expression. J Am Soc Nephrol. 2014;25(4):784-797.
38. Mailloux RJ, Xuan JY, McBride S, Maharsy W, Thorn S, Holterman CE, Kennedy CRJ, Rippstein P, Dekemp R, Da Silva J, Nemer J, Lou M, Harper ME. Glutaredoxin-2 is required to control oxidative phosphorylation in cardiac muscle by mediating deglutathionylation reactions. J Biol Chem. 2014; 289(21):14812-14828.
39. Read NC, Gutsol A, Holterman CE, Carter A, Coulombe J, Gray DA, Kennedy CRJ. Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis. Biochim Biophys Acta. 2014;1842(7):1028-1040.
40. Thibodeau JF, Holterman CE, Burger D, Read NC, Reudelhuber TL, Kennedy CRJ. A novel mouse model of advanced diabetic kidney disease. PLoS One. 2014;9(12):e113459.
41. Cherney DZI, Zinman B, Kennedy CRJ, Moineddin R, Lai V, Yang S, Miller JA, Prokopec SD, Boutros PC, Scholey JW, Reich HN. Long-term hemodynamic and molecular effects persist after discontinued renin-angiotensin system blockade in patients with type 1 diabetes mellitus. Kidney Int. 2013;84(6):1246-1253.
42. Cuerrier CM, Chen YX, Tremblay D, Rayner K, McNulty M, Zhao X, Kennedy CRJ, de BelleRoche J, Pelling AE, O'Brien ER. Chronic over-expression of heat shock protein 27 attenuates atherogenesis and enhances plaque remodeling: A combined histological and mechanical assessment of aortic lesions. PLoS One. 2013;8(2):e55867.
43. Drapeau N, Lizotte F, Denhez B, Guay A, Kennedy CRJ, Geraldes P. Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes. Am J Physiol Endocrinol Metab. 2013; 304(11):E1188-98.
44. Patrick C, Wang GS, Lefebvre DE, Crookshank JA, Sonier B, Eberhard C, Mojibian M, Kennedy CRJ, Brooks SP, Kalmokoff ML, Maglio M, Troncone R, Poussier P, Scott FW. Promotion of autoimmune diabetes by cereal diet in the presence or absence of microbes associated with gut immune activation, regulatory imbalance, and altered cathelicidin antimicrobial Peptide. Diabetes. 2013; 62(6):2036-47.
45. Sedeek M, Gutsol A, Montezano AC, Burger D, Nguyen Dinh Cat A, Kennedy CRJ, Burns KD, Cooper ME, Jandeleit-Dahm KA, Page P, Szyndralewiez C, Heitz F, Hébert RL, Touyz RM. Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes. Clin Sci (Lond). 2013; 124(3):191-202.
46. Thibodeau JF, Nasrallah R, Carter A, He Y, Touyz RM, Hébert RL, Kennedy CRJ. PTGER1 Deletion Attenuates Renal Injury in Diabetic Mouse Models. Am J Pathol. 2013;183(6):1789-802.
47. Burger D, Kwart DG, Montezano AC, Read NC, Kennedy CRJ, Thompson CS, Touyz RM. Microparticles induce cell cycle arrest through redox-sensitive processes in endothelial cells: Implications in vascular senescence. J Am Heart Assoc. 2012;1(3):e001842.
48. Nadarajah R, Milagres R, Dilauro M, Gutsol A, Xiao F, Zimpelmann J, Kennedy CRJ, Wysocki J, Batlle D, Burns KD. Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice. Kidney Int. 2012;82(3):292-303.
49. Xiao F, Hiremath S, Knoll G, Zimpelmann J, Srivaratharajah K, Jadhav D, Fergusson D, Kennedy CRJ, Burns KD. Increased urinary angiotensin-converting enzyme 2 in renal transplant patients with diabetes. PLoS One. 2012;7(5):e37649.
50. Cybulsky AV, Kennedy CRJ. Podocyte injury associated with mutant alpha-actinin-4. J Signal Transduction. 2011:1-11.
51. A. V. Cybulsky, T. Takano, J. Papillon, J. Guillemette, A. M. Herzenberg, Kennedy CRJ. Podocyte injury and albuminuria in mice with podocyte-specific overexpression of the Ste20-like kinase, SLK. Am J Pathol. 2010;177(5):2290-99.
52. Faour WH, Thibodeau JF, Kennedy CRJ. Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes. Cell Signal. 2010;22(8):1222-30.
53. Kennedy CRJ. What type of VEGF do you need? J Am Soc Nephrol. 2010;21(9):1410-12.
54. Sedeek M, Callera GE, Montezano A, Gutsol A, Heitz F, Szyndralewiez C, Page P, Kennedy CRJ, Burns KD, Touyz RM, Hébert RL. Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney - implications in type 2 diabetic nephropathy. Am J Physiol Renal Physiol. 2010;299(6):F1348-58.
55. Stitt-Cavanagh EM, Faour WH, Takami K, Carter A, Vanderhyden B, Guan Y, Schneider A, Breyer MD, Kennedy CRJ. A maladaptive role for EP4 receptors in podocytes. J Am Soc Nephrol. 2010; 21(10):1678-90.
56. Cherney DZ, Scholey JW, Zhou J, Zimpelmann J, Kennedy CRJ, Burns KD, Lai V, Miller JA. Endothelial nitric oxide synthase gene polymorphisms and the renal hemodynamic response to L-arginine. Kidney Int. 2009;75(3):327-32.
57. Cybulsky AV, Takano T, Papillon J, Bijian K, Guillemette J, Kennedy CRJ. Glomerular epithelial cell injury associated with mutant alpha-actinin-4. Am J Physiol Renal Physiol. 2009;297(4):F987-95.
58. Konger RL, Billings SD, Prall NC, Katona TM, Dasilva SC, Kennedy CRJ, Badve S, Perkins SM, Lacelle PT. The EP1 subtype of prostaglandin E2 receptor: Role in keratinocyte differentiation and expression in non-melanoma skin cancer. Prostaglandins Leukot Essent Fatty Acids. 2009;81(4):279-90.
59. Michaud JL, Hosseini-Abardeh M, Farah K, Kennedy CRJ. Modulating alpha-actinin-4 dynamics in podocytes. Cell Motil Cytoskeleton. 2009;66(3):166-78.
60. Michaud JL, Stitt-Cavanaugh E, Endlich N, Endlich K, De Repentigny Y, Kothary R, Kennedy CRJ. Mice with podocyte-specific overexpression of wild type alpha-actinin-4 are healthy controls for K256E-alpha-actinin-4 mutant transgenic mice. Transgenic Res. 2009;19(2):285-9.
61. Sedeek M, Hébert RL, Kennedy CRJ, Burns KD, Touyz RM. Molecular mechanisms of hypertension: Role of Nox family NADPH oxidases. Curr Opin Nephrol Hypertens. 2009;18(2):122-127.
62. Stitt-Cavanaugh E, MacLoed L, Kennedy, CRJ. The podocyte in diabetic kidney disease. TheScientificWorld. 2009;9:1127-39.
63. Faour WH, Gomi K, Kennedy CRJ. PGE2 induces COX-2 expression in podocytes via the EP4 receptor through a PKA-independent mechanism. Cell Signal. 2008;20(11):2156-64.
64. Sequeira J, Boily G, Bazinet S, Saliba S, He X, Jardine K, Kennedy CRJ, Staines W, Rousseaux C, Mueller R, McBurney MW. sirt1-null mice develop an autoimmune-like condition. Exp Cell Res. 2008;314(16):3069-74.
65. Cheng H, Wang S, Jo YI, Hao CM, Zhang M, Fan X, Kennedy CRJ, Breyer MD, Moeckel GW, Harris RC. Overexpression of cyclooxygenase-2 predisposes to podocyte injury. J Am Soc Nephrol. 2007; 18(2):551-9.
66. Cherney DZ, Scholey JW, Cattran DC, Kang AK, Zimpelmann J, Kennedy CRJ, Lai V, Burns KD, Miller JA. The effect of oral contraceptives on the nitric oxide system and renal function. Am J Physiol Renal Physiol. 2007;293(5):F1539-44.
67. Kennedy CRJ, Xiong H, Rahal S, Vanderluit J, Slack RS, Zhang Y, Guan Y, Breyer MD, Hébert RL. Urine concentrating defect in prostaglandin EP1-deficient mice. Am J Physiol Renal Physiol. 2007;292(2):F868-75.
68. Michaud JL, Kennedy CRJ. The podocyte in health and disease: Insights from the mouse. Clin Sci (Lond). 2007;112(6):325-35.
69. Michaud JL, Chaisson KM, Parks RJ, Kennedy CRJ. FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes. Kidney Int. 2006;70(6):1054-61.
70. Miller JA, Cherney DZ, Duncan JA, Lai V, Burns KD, Kennedy CRJ, Zimpelmann J, Gao W, Cattran DC, Scholey JW. Gender differences in the renal response to renin-angiotensin system blockade. J Am Soc Nephrol. 2006;17(9):2554-60.
71. Rahal S, McVeigh LI, Zhang Y, Guan Y, Breyer MD, Kennedy CRJ. Increased severity of renal impairment in nephritic mice lacking the EP1 receptor. Can J Physiol Pharmacol. 2006;84(8-9):877-85.
72. Bijian K, Takano T, Papillon J, Le Berre L, Michaud JL, Kennedy CRJ, Cybulsky AV. The actin cytoskeleton regulates extracellular matrix-dependent survival signals in glomerular epithelial cells. Am J Physiol Renal Physiol. 2005;289(6):58-66.
73. Ahmed SB, Kang AK, Burns KD, Kennedy CRJ, Lai V, Cattran DC, Scholey JW, Miller JA. Effects of oral contraceptive use on the renal and systemic vascular response to angiotensin II infusion. J Am Soc Nephrol. 2004;15(3):780-6.
74. Martineau LC, McVeigh LI, Jasmin BJ, Kennedy CRJ. p38 MAP kinase mediates mechanically induced COX-2 and PG EP4 receptor expression in podocytes: Implications for the actin cytoskeleton. Am J Physiol Renal Physiol. 2004;286(4):F693-701.
75. Lemieux LI, Rahal SS, Kennedy CRJ. PGE2 reduces arachidonic acid release in murine podocytes: evidence for an autocrine feedback loop. Am J Physiol Cell Physiol. 2003;284(2):53-2.
76. Michaud JL, Lemieux LI, Dubé M, Vanderhyden BC, Robertson SJ, Kennedy CRJ. Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4. J Am Soc Nephrol. 2003;14(5):1200-11.
77. Breyer RM, Kennedy CRJ, Zhang Y, Guan Y, Breyer MD. Targeted gene disruption of the prostaglandin E2 EP2 receptor. Adv Exp Med Biol. 2002;507:321-6.
78. Breyer RM, Kennedy CRJ, Zhang Y, Breyer MD. Structure-function analyses of eicosanoid receptors. Physiologic and therapeutic implications. Ann N Y Acad Sci. 2000;905:221-31.
79. Li X, Okada Y, Pilbeam CC, Lorenzo JA, Kennedy CRJ, Breyer RM, Raisz LG. Knockout of the murine prostaglandin EP2 receptor impairs osteoclastogenesis in vitro. Endocrinology. 2000;141(6):2054-61.
80. Kennedy CRJ, Zhang Y, Brandon S, Guan Y, Coffee K, Funk CD, Magnuson MA, Oates JA, Breyer MD, Breyer RM. Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor. Nat Med. 1999;5:217-20.
81. Chan AC, Wagner M, Kennedy CRJ, Chen E, Lanuville O, Mezl VA, Tran K, Choy PC. Vitamin E up-regulates arachidonic acid release and phospholipase A2 in megakaryocytes. Mol Cell Biochem. 1998;189:153-9.
82. Chan AC, Wagner M, Kennedy CRJ, Mroske C, Proulx P, Laneuville O, Tran K, Choy PC. Vitamin E upregulates phospholipase A2, arachidonic acid release and cyclooxygenase in endothelial cells. Akt. Ernähr.-Med. 1998;22:152-159.
83. Kennedy CRJ, Proulx PR, Hébert RL. Bradykinin-induced translocation of cytoplasmic phospholipase A2 in MDCK cells. Can J Physiol Pharmacol. 1997;75:563-7.
84. Kennedy CRJ, Hébert RL, Do MT, Proulx PR. Bradykinin-stimulated arachidonic acid release from MDCK cells is not protein kinase C dependent. Am J Physiol. 1997;273(5):C1605-12.
85. Lal MA, Kennedy CRJ, Proulx PR, Hébert RL. Bradykinin-stimulated cPLA2 phosphorylation is protein kinase C dependent in rabbit CCD cells. Am J Physiol. 1997;273:F907-15.
86. Kennedy CRJ, Proulx PR, Hebert RL. Role of PLA2, PLC, and PLD in bradykinin-induced release of arachidonic acid in MDCK cells. Am J Physiol. 1996;271:C1064-72.
87. Kennedy CRJ, Proulx PR, Hebert RL. Regulation of bradykinin-stimulated phospholipase C and arachidonic acid release by protein kinase A in MDCK-D1 cells. Biochim Biophys Acta. 1995; 1258:206-14.
88. Kennedy CRJ, Slack R, Ding LX, Aubry H, Proulx P. Transfer of arachidonyl groups within the lipids of two human neuroblastoma cell lines. Biochim Biophys Acta. 1994;1211:326-34.

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