Publications
Selected Publications
Top Publications
Cell-based Regenerative Therapy
1. Allan DS, Tieu A, Lalu M, Burger D. Mesenchymal stromal cell-derived extracellular vesicles for regenerative therapy and immune modulation: Progress and challenges. Stem Cells Transl Med, 2019 (Aug 14, epub ahead of print)
2. Rizk M*, Aziz J*, Shorr R, Allan DS. Use of umbilical cord blood for novel applications in regenerative therapy and immune modulation: an updated systematic scoping review. Biol Blood Marrow Transplant, 2017; 23:1607-1613. [PMID 28602892]
Hematopoietic Stem Cells & Transplantation
1. Allan D, Kiernan J*, Dibdin N, Bartlett D, Campbell T, Mostert K, Halpenny M, Ganz K, Gragert L, Maiers M, Petrazsko T, Elmoazzen H. Reducing ethnic disparity in access to high quality HLA-matched cord blood units for transplantation: analysis of the Canadian Blood Services’ Cord Blood Bank inventory. Transfusion, 2019; 59: 2382-2388.
2. Greco-Stewart V, Kiernan J*, Killeen D, Haun S, Mercer D, Young K, Liwski R, Allan DS. Unrelated donor choices for allogeneic hematopoietic cell transplantation in Canada: an evaluation of factors influencing donor selection. Transfusion, 2018; 58: 718-725. [PMID 29277913].
All Other Publications
Selected Peer-reviewed Publications [past 4 years]
Trainees under my supervision are marked with (*)
Cell-based Regenerative Therapy: Discovery & Translational Research
1. Aziz J*, Liao G*, Adams Z*, Rizk M*, Shorr R, Allan DS. Controlled clinical studies using umbilical cord blood for regenerative therapy: lessons from an updated systematic review of the literature. Cytotherapy, 2019 (accepted).
2. Allan DS, Tieu A, Lalu M, Burger D. Mesenchymal stromal cell-derived extracellular vesicles for regenerative therapy and immune modulation: Progress and challenges. Stem Cells Transl Med, 2019 (in press).
3. Vinas JL*, Spence M, Gutsol A, Knoll W, Burger D, Zimpelmann J, Allan DS, Burns KD. Receptor-Ligand Interaction Mediates Targeting of Endothelial Colony Forming Cell-derived Exosomes to the Kidney after Ischemic Injury. Sci Reports, 2018; 8:16320. doi: 10.1038/s41598-018-34557-7. [PMID 30397255]
4. Rizk M*, Aziz J*, Shorr R, Allan DS. Use of umbilical cord blood for novel applications in regenerative therapy and immune modulation: an updated systematic scoping review. Biol Blood Marrow Transplant, 2017; 23:1607-1613. [PMID 28602892]
5. Fraineau S*, Palii CG, McNeill B, Ritso M, Shelley WC, Prasain N, Chu A, Vion E, Rieck K, Nilufar S, Perkins TJ, Rudnicki MA, Allan DS, Yoder MC, Suuronen EJ, Brand M. Epigenetic activation of pro-angiogenic signaling pathways in human endothelial progenitors increases vasculogenesis. Stem Cell Reports, 2017; 9:1573-1587. [PMID 29033304]
6. Barrera-Ramirez J*, Lavoie J, Maganti HB, Stanford WL, Ito C, Sabloff M, Brand M, Rosu-Myles M, Le Y+, Allan DS+. Micro RNA profiling of exosomes from marrow-derived mesenchymal stromal cells in patients with acute myeloid leukemia: implications in leukemogenesis. Stem Cell Rev Rep, 2017; 13:817-825. [PMID 28918518]
7. Viñas JL*, Burger D, Haneef R, Knoll W, Campbell P, Gutsol A, Carter A, Allan DS, Burns KD. Exosomal Transfer of MicroRNA-486-5p from Human Endothelial Colony Forming Cells Inhibits Hypoxic Endothelial Cell Injury. Kidney International, 2016; 90:1238-1250. [PMID: 27650731]
8. Park A*, Barrera-Ramirez J*, Ranasinghe I*, Pilon S*, Fergusson D, Allan DS. The role of HMG-coA reductase inhibition on the regenerative capacity of mesenchymal stromal cells and endothelial progenitors: a systematic review of clinical and preclinical studies. Stem Cell Rev, 2016; 12:327-339. [PMID: 26873165]
9. Le Y*, Fraineau S*, Chandran P*, Brand M, Sabloff M, Lavoie JR, Gagne R, Rosu-Myles M, Yauk CL, Richardson R, Allan DS. Adipogenic mesenchymal stromal cells from bone marrow and their hematopoietic supportive role: towards an understanding of a permissive marrow microenvironment in acute myeloid leukemia. Stem Cell Rev & Rep, 2016; 12:235-244. [PMID: 26649729]
Hematopoietic Stem Cell Donation, Transplantation & Biology
1. Allan D, Kiernan J*, Dibdin N, Bartlett D, Campbell T, Mostert K, Halpenny M, Ganz K, Gragert L, Maiers M, Petrazsko T, Elmoazzen H. Reducing ethnic disparity in access to high quality HLA-matched cord blood units for transplantation: analysis of the Canadian Blood Services’ Cord Blood Bank inventory. Transfusion, 2019 (accepted).
2. Visram A*, Aziz J*, Bryant A*, Morris G, Zhang T, Cieniak C, Hamelin L, Landry C, Atkins H, Huebsch L, Al-Touri S, Fulcher J, Sabloff M, Kekre N, Bredeson C, Allan DS. Effect of donor age and donor relatedness on time to allogeneic transplantation in acute leukemia. Biol Blood Marrow Transplant, 2018; 24:2466-2470. [PMID 30036572]
3. Monaghan M*, Rizk M*, Pilon S*, Iyengar A*, Shorr R, Tay J, Maze D, Bredeson CN, Hutton B, Allan DS. Evidence networks from RCTs addressing donor selection and source of cells used in allogeneic hematopoietic cell transplantation. Transfusion Medicine, 2018; 28:371-379. [PMID 29380924]
4. Fingrut W*, Rikrhaj K*, Allan DS. Targeted Recruitment of Male Donors for Allogeneic Hematopoietic Cell Transplantation: a review of the evidence. Vox Sang, 2018; 113:307-316. [PMID 29359335]
5. Greco-Stewart V, Kiernan J*, Killeen D, Haun S, Mercer D, Young K, Liwski R, Allan DS. Unrelated donor choices for allogeneic hematopoietic cell transplantation in Canada: an evaluation of factors influencing donor selection. Transfusion, 2018; 58: 718-725. [PMID 29277913].
6. Adams Z*, Morris G, Campbell T, Mostert K, Dibdin N, Fearon M, Elmoazzen H, Mercer D, Young K, Allan DS. Risk of exposure to Zika virus and impact on cord blood banking and unrelated donors for hematopoietic cell transplantation: the Canadian Blood Services’ experience. Biol Blood Marrow Transplant, 2018; 24:861-865. [PMID 29253552]
7. Bryant A*, Mallick R, Huebsch L, Allan D, Atkins H, Anstee G, Sabloff M, Scrivens N, Maze D, Bredeson C, Kekre N. Low-dose ATG for GVHD prophylaxis in matched unrelated allogeneic HCT. Biol Blood Marrow Transplant, 2017; 23:2096-2101. [PMID 28821454]
8. Fingrut W*, Parmar S, Cuperfain A, Rikhraj K, Charman E, Ptak E, Kahlon M, Graham A, Leong S, Wang Y, Yu J, Arora N, Suppiah R, Li E, Lee A, Welsh C, Benzaquen M, Thatcher A, Baharmand I, Ladd A, Petraszko T, Allan D, Messner H. The Stem Cell Club: A Model for Unrelated Stem Cell Donor Recruitment. Transfusion, 2017; 57:2928-2936. [PMID 28944484]
9. Aziz J*, Morris G, Rizk M*, Shorr R, Mercer D, Young K, Allan DS. Cryopreservation of adult unrelated donor products in HCT: the OneMatch experience and systematic review of the literature. Transfusion, 2017; 57:2782-2789. [PMID 28963719]
10. Kiernan J*, Damien P*, Monaghan M*, Shorr R, McIntyre L, Fergusson DA, Tinmouth A, Allan DS. Clinical studies of ex vivo expanded hematopoietic stem cells to accelerate engraftment following umbilical cord blood transplantation: a systematic review. Transf Med Rev, 2017; 31:173-182. Epub 2016 Dec 23. [PMID 28087163]
11. Christou G*, Iyengar A*, Shorr R, Tinmouth A, Saidenberg E, Maze D, Tay J, Bredeson C, Allan DS. Optimal transfusion practices following allogeneic hematopoietic cell transplantation: a systematic scoping review of evidence from randomized controlled trials. Transfusion, 2016; 56:2607-2614. [PMID: 27465524]
12. Atkins A, Bowman M, Allan D, Anstee G, Arnold D, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Galal A, Halpenny M, Huebsch L, Lapierre Y, Lee H, Martin L, McDiarmid S, O’Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS. Immunoablative therapy followed by purified autologous hematopoietic stem cell transplantation halts inflammation in the central nervous system and facilitates recovery from multiple sclerosis. Lancet, 2016; 388:576-585. [PMID: 27291994]
13. Rizk M*, Monaghan M*, Shorr R, Kekre N, Bredeson CN, Allan DS. Heterogeneity in studies of mesenchymal stromal cells to treat or prevent GVHD: a scoping review of the literature. Biol Blood Marrow Transplant, 2016; 22:1416-1423. [PMID: 27130504]
14. Dyba J*, Tinmouth A, Bredeson C, Matthews J, Allan DS. Eltrombopag after allogeneic hematopoietic cell transplantation in a case of poor graft function and systematic review of the literature. Transfusion Medicine, 2016; 26:202-207. [PMID: 27046441].
15. Allan DS, Scrivens N, Lawless T, Mostert K, Oppenheimer L, Walker M, Petraszko T, Elmoazzen H. Delayed clamping of the umbilical cord following delivery and implications for public cord blood banking. Transfusion, 2016; 56:662-665. [PMID: 26585667]PubMed Listings
