Abadeh, A., Shehadeh, S., Betschel, S., Waserman, S., Cameron, DW., Cowan, J. (2023). Clinical outcomes of immunoglobulin treatment for patients with secondary antibody deficiency: Data from the Ontario immunoglobulin treatment case registry. PLOS ONE. 18(11):e0294408. Doi: https://doi.org/10.1371/journal.pone.0294408

Mir, A., Ivory, C., Cowan, J. (2023). Concurrence of Familial Mediterranean fever and Behçet's disease: A case report and review. Journal of Medical Case Reports.17:438. Doi: https://doi.org/10.1186/s13256-023-04185-5

Pratt, AJ., Purssell, A., Zhang, T., Luks, VPJ., Bauza, X., Mulpuru, S., Kirby, M., Aaron, SD., Cowan, J. (2023). Complexity in clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease. BMC Pulmonary Medicine, 23(1):298. Doi: https://doi.org/10.1186/s12890-023-02587-1

Cowan, J., Amson, A., Christofides, A., Chaga, Z. (2023). Monoclonal antibodies as COVID-19 prophylaxis therapy in immunocompromised patient populations. International Journal of Infectious Diseases. 134(Sept):228-238. Doi: 10.1016/j.ijid.2023.06.021

Milne, K.M., Cowan, J., Schaeffer, M.R., Voduc, N., Corrales-Medina, V., Lavoie, K.L., Chirinos, J.A., Puyat, J.H., Abdallah, S.J., Guenette, J.A. (2023). Exercise responses and mental health symptoms in COVID-19 survivors with dyspnoea. ERJ Open Research. 9(3):1-42. Doi: 10.1183/23120541.00606-2022

All Other Publications

Yoo, S., Garg, E., Eliott, L. T., Hung, R. J., Halevy, A. R., Brooks, J. D., Bull, S. B., Gagnon, F., Greenwood, C. MT., Lawless, J. F., Paterson, A. D., Sun, L., Zawati, M. H., Lerner-Ellis, J., Abraham, R. JS., Birol, I., Bourque, G., Garant, J-M., Gosselin, C., Li, J., Whitney, J., Thiruvahindrapuram, B., Herbrick, J., Lorenti, M., Reuter, M., Liu, S., Allen, U., Bernier, F. P., Biggs, C. M., Cheung, A. M., Cowan, J., Herridge, M., Maslove, D. M., McGeer, A., Modi, B. P., Mooser, V., Morris, S. K., Ostrowski, M. K., Parekh, R. S., Pfeffer, G., Suchowersky, O., Taher, J., Turvey, S. E., Upton, J., Warren, R. L., Yeung, R. SM., Aziz, N., Knoppers, B. M., Lathrop, M., Jones, S. JM., Scherer, S. W., Strug, L. J. (2023). HostSeq: a Canadian whole genome sequencing and clinical data resource. BMC Genetics, 24(1):26. https://doi.org/10.1186/s12863-023-01128-3

Quinn, KL.., Lam, G.Y., Walsh, J.F., Bhéreur, A., Brown, A.D., Chow, C.W., Chung, C.K.Y., Cowan, J., Crampton, N., Décary, S., Falcone, E.L., Graves, L., Gross, D.P., Hanneman, K., Harvey, P.J., Holmes, S., Katz, G.M., Parhizgar, P., Sharkawy, A., Tran K.C., Waserman, S., Zannella, V.E., Cheung, A.M. (2023). Cardiovascular Considerations in the Management of People with Suspected Long COVID. The Canadian Journal of Cardiology. 39(6): 741-753. Doi: 10.1016/j.cjca.2023.04.003.

Jo, D.H., Kaczmarek, S., Shin, O.S., Wang, L., Cowan, J., McComb.S., Lee, S.H. (2023). Simultaneous engineering of natural killer cells for CAR transgenesis and CRISPR-Cas9 knockout using virus-like particles. Molecular Therapy – Methods & Clinical Development. 15(29):173-184. Doi: 10.1016/j.omtm.2023.03.006

Unniyanar, D., Shea, B., Cameron, D.W., Cowan, J. (2023). Levels of Immunoglobulin Isotypes in Serum and Respiratory Samples of Patients with Chronic Obstructive Pulmonary Disease: Protocol for a Systematic Review and Meta-Analysis. BMJ Open. 13(2):e064307. Doi: 10.1136/bmjopen-2022-064307

Brownlee, S., Allen, C., Kana’an, M., Cameron, DW., Cowan, J. (2022). Cutaquig® is well tolerated in immunodeficient patients who did not tolerate other subcutaneous immunoglobulin products. Hematology Reports. 14(4):342-348. DOI: 10.3390/hematolrep14040048

Cowan, J., Pakhale, S., Angel, J.B. (2022). Mulch pneumonitis in a patient with chronic granulomatous disease. Canadian Medical Association Journal (CMAJ). 194(44):E1510. DOI: 10.1503/cmaj.220713

Yazji, B., Voduc, N., Mulpuru, S., Cowan, J. (2022) Pulmonary sequelae of SARS-CoV-2 infection and factors associated with persistent abnormal lung function at six months after infection: prospective cohort study. PLoS One. 17(11):e0277624. DOI: https://doi.org/10.1371/journal.pone.0277624

Asare-Werehene, M., McGuinty, M., Vranjkovic, A., Galipeau, Y., Cowan, J., Cameron, DW., Cooper, C.L., Langlois, M-A., Crawley, A.M., Tsang, B.K. (2022). Longitudinal profiles of plasma gelsolin, cytokines and antibody expression predict COVID-19 severity and hospitalization outcomes. Frontiers Immunology. 6:1011084 DOI: https://doi.org/10.1101/2022.06.01.22275882

Hachem, Y., Abdallah, S.J., Rueda, S., Mehra, K., Rup, J., Wiese, J., Cowan, J., Vigano, A., Costiniuk, C. (2022) Healthcare Practitioner Perceptions on Barriers Impacting Cannabis Prescribing Practices. BMC Complementary Medicine and Therapies. 22:237. DOI: https://doi.org/10.1186/s12906-022-03716-9

Hatcher, S., Werier, J., Edgar, N., Booth, J., Cameron, D.W., Corrales-Medina, V., Corsi, D., Cowan, J., Giguère, P., Kaluzienski, M., Marshall, S., Mestre, T., Mulligan, B., Orpana, H., Pontefract, A., Stafford, D., Thavorn, K., Trudel, G. (2022). Enhancing COVID Rehabilitation with Technology (ECORT): Protocol for an open-label, single site randomized controlled trial evaluating the effectiveness of electronic case management for individuals with persistent COVID-19 symptoms. Trials. 23(1):728. DOI: https://doi.org/10.21203/rs.3.rs-1723719/v1

Munoz, C., MacDonald, B., Pham-Huy, A., Vaudry, W., Permica, J.M., Boucher, F.D., Constantinescu, C., Sadarangani, M., Bettinger, J.A., Tapiero, B., Morris, S.K., McConnnell, A., Cowan, J., Zafack, J., Upton, J., Abdurrahman, Z., McHenry, M., Hildebrand., K.J., Noya, F., Serres, G.D., Halperin, S.A., Top, K. (2022). Revaccination and adverse event recurrence in patients with adverse events following immunization. The Journal of Pediatrics. 250:45-53.e3.
DOI: https://doi.org/10.1016/j.jpeds.2022.07.019

Keith, P.K., Cowan, J., Kanani, A, Kim, H, Lacuesta, G, Lee, J.K., Chen, J., Park, M., Gladiator, A. (2022). Transitioning subcutaneous immunoglobulin 20% therapies in patients with primary and secondary immunodeficiencies: a Canadian Real-World Study. Allergy, Asthma & Clinical Immunology. 18(1):70. DOI: https://doi.org/10.1186/s13223-022-00709-8

Anderson, J. T., Cowan, J., Condino-Neto, A., Levy, D., Prusty, S. (2022). Health-Related Quality of Life in Primary Immunodeficiencies: Impact of Delayed Diagnosis and Treatment Burden. Clinical Immunology. 236:108931 DOI: 10.1016/j.clim.2022.108931

Schaeffer, M., Cowan, J., Milne, K., Puyat, J., Voduc, N., Corrales-Medina, V., Lavoie, K., Mulloy, A., Chirinos, J., Abdallah, S., Guenette, J. (2022). Cardiorespiratory physiology, exertional symptoms, and psychological burden in post-COVID-19 fatigue. Respiratory Physiology & Neurobiology. 302(Aug):103898. DOI: https://doi.org/10.1016/j.resp.2022.103898

Ieta, S., Ivory, C., Cowan, J. (2022). Duration of prednisone treatment before development of Pneumocystis jerovecii pneumonia in patients with vasculitis: A Case Series. Journal of the Association of Medical Microbiology and Infectious Disease Canada. 7(2):117-124. DOI: https://doi.org/10.3138/jammi-2021-0031

Cowan. J., Mulpuru, S., Abdallah, S., Chopra, A., Purssell, A., McGuinty, M., Alvarez, G., Giulivi, A., Corrales-Medina, V., MacFadden, D., Boyle, L., Hasimja, D., Thavorn, K., Mallick, R., Aaron, S., Cameron, DW. (2021). A randomized double-blind placebo-control feasibility trial of immunoglobulin treatment for prevention of recurrent acute exacerbations of COPD. International Journal of COPD. 16:3275-3284. DOI:10.2147/COPD.S338849

Marko, R., Hajjar, J., Nzeribe, V., Pittman, M., Deslandes, V., Sant, N., Cowan, J., Kyermentang, K., Ramsay, T., Zelenitsky, S., Kanji, S. (2021). Therapeutic Drug Monitoring of Vancomycin in Adult Patients with Methicillin-Resistant Staphylococcus aureus Bacteremia or Pneumonia. The Canadian Journal of Hospital Pharmacy. 74(4):334-43. DOI: 10.4212/cjhp.v74i4.3195

Patel, V., Cameron, D.W., Cowan, J. (2021). Immunoglobulin Replacement Therapy Discontinuation in Patients with Antibody Deficiency Secondary to Hematological Malignancy: A Single-Center Study. Hematological Oncology. 34(4):584-588. DOI: 10.1002/hon.2900

Poenaru, S., Abdallah, S.J., Corrales-Medina, V., Cowan, J. (2021). COVID-19 and post-infectious myalgic encephalomyelitis/chronic fatigue syndrome: A narrative review. Therapeutic Advances in Infectious Disease. 8(63):830-839. DOI: 10.1177/20499361211009385

Abdallah, S., Voduc, N., Corrales-Medina, V., McGuinty, M., Pratt, A., Chopra, A., Law, A., Garuba, H., Thavorn, K., Reid, R., Lavoie, K., Crawley, A., Chirinos, J., Cowan, J. (2021). Symptoms, pulmonary function and functional capacity four months after COVID-19. Annals of the American Thoracic Society. 18(11):1912-1917. DOI: 10.1513/AnnalsATS.202012-1489RL

Azad, T., Rezaei, R., Singaravelu, R., Jamieson, T.R., Crupi, M., Surendran, A., Poutou, P., Taklifi, P., Cowan, J., Cameron, D.W., Ikow, C. (2021). A high-throughput NanoBiT-based serological assay detects SARS-CoV-2 seroconversion. Nanomaterials. 11(3):807. DOI: https://doi.org/10.3390/nano11030807

Unninayar, D., Abdallah, S., Cameron, D.W., Cowan, J. (2021). Polyvalent immunoglobulin as a potential treatment option for patients with recurrent COPD exacerbations. International Journal of Chronic Obstructive Pulmonary Disease.16:545-552. DOI: 10.2147/COPD.S283832

Leeies, M., Gershengorn, H.B., Charbonney, E., Kumar A., Fergusson, D., Turgeon, A., Cowan, J., Paunovic, B., Embil, J., Garland, A., Houston, D.S., Houston, B., Rimmer, E., Siddiqui, F., Cameron, D.W., Murthy, S., Marshall, J.C., Fowler, R., Zarychanski, R. (2021). Intravenous immune globulin in septic shock: a Canadian national survey of critical care medicine and infectious disease specialist physicians. Canadian Journal of Anesthesia. 68(8):1310-1311. DOI: https://doi.org/10.1007/s12630-021-01941-3

Anderson, J., Bonagura, V., Cowan, J., Hsu, C., Mustafa, S.S., Patel, N., Routes, J., Sriaroon, P., Vinh, D., Hofmann, J., Praus, M., Rojavin, M. (2021). Safety and Tolerability of Subcutaneous IgPro20 at High Infusion Parameters in Patients with Primary Immunodeficiency: Findings from the Pump-Assisted Administration Cohorts of the HILO Study. Journal of Clinical Immunology. 41:458-469. DOI: https://doi.org/10.1007/s10875-020-00912-5

Thabet, C., Sherazi, A., Cowan, J. (2020). Toxoplasmosis, Cryptosporidiosis, and Isosporiasis in Non-HIV Immunocompromised Patients, a single-center study, Ottawa, Canada. Journal of the Association of Medical Microbiology and Infectious Disease Canada. 5(4):239-244. DOI: 10.3138/jammi-2020-0024

Suleman, A., Cameron, D.W., Corrales-Medina, V., McCudden, C., Cowan, J. (2020). Evaluation of the protein gap for detection of abnormal serum gammaglobulin level: an imperfect predictor. Clinical Chemistry and Laboratory Medicine (CCLM). 59(5):869-874. DOI https://doi.org/10.1515/cclm-2020-1286

McGuinty, M., Angel, J., Cooper, C., Cowan, J., Macpherson, P., Kumar, A., Murthy, S., Sy, R., Dennehy, M., Tremblay, N., Byrareddy, S., Cameron, D.W. (2020). Vedolizumab treatment across antiretroviral treatment interruption in chronic HIV infection: The HAVARTI protocol for a pilot dose-ranging clinical trial to assess safety, tolerance, immunological and virological activity. BMJ Open. 10:e041359. DOI: 10.1136/bmjopen-2020-041359

Cowan, J., Bonagura, V., Lugar, P., Maglione, P., Patel, N., Vinh, D., Hofmann, J., Praus, M., Rojavin, M. (2020). Safety and tolerability of manual push administration of subcutaneous IgPro20 at high infusion rates in patients with primary immunodeficiency: findings from the manual push administration cohort of the HILO study. Journal of Clinical Immunology. 40(7):1-10. DOI: 10.1007/s10875-020-00876-6

Patel, V., Cowan, J. (2020) Discontinuation of immunoglobulin replacement therapy in patients with secondary antibody deficiency. Expert Review of Clinical Immunology. 16(7):711-716. DOI: 10.1080/1744666X.2020.1788939

Patel, V., Desjardins, M., Cowan, J. (2019). Shift in epidemiology of cryptococcal infections in Ottawa with high mortality in non-HIV immunocompromised patients. Journal of Fungi. 10:(5):E104. DOI: 10.3390/jof5040104

Dinh, T., Oh, J., Cameron, DW, Lee SH, Cowan, J. (2019). Differential immunomodulation of T-cells by immunoglobulin replacement therapy in primary and secondary antibody deficiency. PLOS ONE. 14(10):e0223861. DOI: 10.1371/journal.pone.0223861

Suleman, A., Padmore, R., Faught, C, Cowan, J. (2019). Disseminated cryptococcal infection in a patient with treatment-naïve chronic lymphocytic leukemia (CLL). IDCases.17:E00566. DOI: 10.1016/j.idcr.2019.e00566

Bourassa-Blanchette, S., Patel, V., Knoll, G., Hutton, B., Fergusson, N., Bennett, A., Tay. J., Cameron, D.W., Cowan, J. (2019). Clinical outcomes of polyvalent immunoglobulin use in solid organ transplant recipients: a systematic review and meta-analysis. Part II: Non-kidney transplant. Clinical Transplantation. 33(6):e13625. DOI: 10.1111/ctr.13625

Bourassa-Blanchette, S., Knoll, G., Hutton, B., Fergusson, N., Bennett, A., Tay, J., Cameron, DW., Cowan, J. (2019). Clinical outcomes of polyvalent immunoglobulin use in solid organ transplant recipients: a systematic review and meta-analysis. Part I: kidney transplant. Clinical Transplantation. 33(7):e13560. DOI: 10.1111/ctr.13560

Suleman, A., Theoret, L., Bourque, P., Pringle, E., Cameron, DW., Cowan, J. (2018). Evaluation of a personalized subcutaneous immunoglobulin treatment program for neurological patients. Canadian Journal of Neurological Sciences. 46(1):38-43. DOI: 10.1017/cjn.2018.363

Cowan, J., Bennett, A., Fergusson, N, McLean, C., Mallick, R., Cameron, DW., Knoll, G. (2018). Incidence rate of post-kidney transplant infection: a retrospective cohort study examining infection rates at a large Canadian multicenter tertiary-care facility. Canadian Journal of Kidney Health and Disease. 5:1-8. DOI: 10.1177/2054358118799692

Cowan, J., Mulpuru, S., Aaron, S., Alvarez, G., Giulivi, A., Corrales-Medina, V., Thiruganasambandamoorthy, V., Thavorn, K., Mallick, R., Cameron, DW. (2018). Study protocol: a randomized, double blind, parallel, two-arm, placebo control trial investigating the feasibility and safety of immunoglobulin treatment in COPD patients for prevention of frequent recurrent exacerbations. Pilot and Feasibility. 4:1-9. DOI: 10.1186/s40814-018-0327-z

Ahn, H., Tay, J., Shea, B., Hutton, B., Shorr, R., Knoll, G., Cameron, B, Cowan, J. (2018). Effectiveness of immunoglobulin prophylaxis in reducing clinical complications of hematopoietic stem cell transplantation: a systematic review and meta-analysis. Transfusion. 58(10):2437-2452. DOI: 10.1111/trf.14656

Cowan, J., Do, T.L., Desjardins, S., Ramotar, K., Corrales-Medina, V., Cameron, D. W. (2018). Prevalence of hypogammaglobulinemia in adult invasive pneumococcal disease. Clinical Infectious Disease. 66(4):564-569. DOI: 10.1093/cid/cix836

Cowan, J., Mulpuru, S., Alvarez, G., Corrales-Medina, V., Cameron, D.W. (2018). COPD exacerbation frequency and serum immunoglobulin G levels. Journal of Allergy and Clinical Immunology. 141(2):830-831. DOI: 10.1016/j.jaci.2017.09.036

Bourassa-Blanchette, S., Knoll, G., Tay, J., Bredeson, C., Cameron, D.W., Cowan, J. (2017). A national survey of screening and management of hypogammaglobulinemia in Canadian transplantation centres. Transplant Infectious Disease. 19(4):e12706. DOI: 10.1111/tid.12706

Lasso, A., Masoudian, P, Quinn, J.G, Cowan, J, Labajian, V, Bonaparte, J.P, Kilty, S. (2016). Long-term low-dose macrolides for Chronic Rhinosinusitis in adults – a systematic review of the literature. Clinical Otolaryngology. 42(3):637-650. DOI: 10.1111/coa.12787

Bourque, PR., Pringle, CE., Cameron, W., Cowan, J., Chardon, JW. (2016). Subcutaneous Immunoglobulin Therapy in the Chronic Management of Myasthenia Gravis: A Retrospective Cohort Study. PLoS ONE. 11(8):e0159993. DOI: 10.1371/journal.pone.0159993

Cowan, J., Hutton, B., Fergusson, N., Bennett, A., Tay, J., Cameron, DW., Knoll, G. (2015). Clinical outcomes of immunoglobulin use in solid organ transplant recipients: protocol for a systematic review and meta-analysis. Systematic Reviews. 4(167):1-5. DOI:10.1186/s13643-015-0156-6

Cowan, J., Gaudet, L., Mulpuru, S., Corrales-Medina, V., Hawken, S., Cameron, C., Aaron, S.D., Cameron, DW. (2015). A retrospective longitudinal within-subject risk interval analysis of immunoglobulin treatment for recurrent acute exacerbation of chronic obstructive pulmonary disease. PLoS ONE. 10(11):e0142205. DOI: 10.1371/journal.pone.0142205

Cowan, J., Cameron, DW., Knoll, G., Tay. J. (2015). Protocol for updating a systematic review of randomised controlled trials on the prophylactic use of intravenous immunoglobulin for patients undergoing haematopoietic stem cell transplantation. BMJ Open. Aug 21; 5(8):e008316. DOI:10.1136/bmjopen-2015-008316

Breau, RH., Kokolo, MB., Punjani, N., Cagiannos, I., Beck, A., Niznick, N., Buenaventura, Ch., Cowan, J., Knoll. G., Momoli, F., Morash, C., Ruzicka, M., Schachkina, S., Tinmouth, A., Xie, HY., Fergusson, DA. (2014). The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis. Transfusion Medicine. 28(3):145-55. DOI: 10.1016/j.tmrv.2014.05.002

Alomari, A., Cowan, J., Turner, L., Cooper, C. (2013). Antidepressant prophylaxis reduces depression risk but does not improve sustained virological response in hepatitis C interferon recipients without depression at baseline: a systematic review and meta-analysis. Canadian Journal of Gastroenterology. 27(10):575-81. DOI: 10.1155/2013/832689

Cowan, J., Panday, S., Filion, LG., Angel, JB., Kumar, A., Cameron DW. (2012) Comparison of interferon-γ-, interleukin (IL)-17- and IL-22-expressing CD4 T cells, IL-22-expressing granulocytes and proinflammatory cytokines during latent and active tuberculosis infection. Clinical and Experimental Immunology,167(2):317-29. DOI: 10.1111/j.1365-2249.2011.04520.x

Cowan (Kohwiwattanagun), J., Kawamura, I., Mitsuyama, M. (2007). Mycobacterial mammalian cell entry protein 1A (Mce1A) - mediated adherence enhances chemokine production from A549 cells. Microbiology and immunology, 51(2), 253-261.