Pillar 1: Acute Stroke Decision-Making
Utility of CT Angiography and CT Perfusion
Development of Guidelines

Pillar 2: Clinical Trial Ethics
When are randomized clinical trials ethically justified?
How do researchers and regulators understand the ethics of RCT justification?
Does fallibility improve upon equipoise as a standard for RCT justification?

Pillar 3: End of Life Care
When is a treatment "futile?"
What does it mean when doctors invoke the doctrine of "double effect?"
How should physicians mediate conflict with patients over aggressive and expensive intervention at the end of life?