Syal, C*, Kosaraju, J*, Hamilton, L, Aumont, A, Chu, A, Sarma, SN, Thomas, J, Seegobin, M, Dilworth, FJ, He, L, Wondisford, FE, Zimmermann, R, Parent, M, Fernandes, K, Wang, J. (2020)
Dysregulated expression of monoacylglycerol lipase is a
marker for anti-diabetic drug metformin-targeted therapy to correct impaired
neurogenesis and spatial memory in Alzheimer's disease,
Theranostics, 10: 6337-6360. (* equal contribution)
Impact Factor: 8.579
https://doi:10.7150/thno.44962.
Gouveia, A, Seegobin, M, Kannangara, TS, He, L, Wondisford, F, Comin, CH, Costa, LDF, Be´i¨que, JC, Lagace, DC, Lacoste, B, Wang, J. (2017) The aPKC-CBP Pathway Regulates Post-stroke Neurovascular Remodeling
and Functional Recovery,
Stem Cell Reports, 9:1735-1744.
Impact Factor: 7.3
https://doi.org/10.1016/j.stemcr.2017.10.021.
Gouveia, A*, Hsu, K*,Niibori,Y, Seegobin, M, Cancino, GI, He, L, Wondisford, FE, Bennett, S, Lagace, D, Frankland, PW, Wang, J. (2016) The aPKC-CBP Pathway Regulates Adult Hippocampal Neurogenesis in an Age-Dependent Manner,
Stem Cell Reports, (* equal contribution) 7:719-734.
Impact Factor: 7.3
http://dx.doi.org/10.1016/j.stemcr.2016.08.007
Fatt, M*, Hsu, K*, He, L, Wondisford, F, Miller, FD, Kaplan, DR, Wang, J. (2015) Metformin acts on two different molecular pathways to enhance adult neural precursor proliferation/self-renewal and differentiation,
Stem Cell Reports 5: 1-8 (* equal contribution)
Impact Factor: 5
http://dx.doi.org/10.1016/j.stemcr.2015.10.014
Wang J; Gallagher D; DeVito LM; Cancino GI; Tsui D; He L; Keller GM; Frankland
PW; Kaplan DR; Miller FD. (2012 Jul 6), Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation,
Cell Stem Cell11 (1):23-35.
Impact Factor: 25
All Other Publications
Loan, A., Syal, C., Lui, M.,
*He, L. and *Wang, J. (*co-corresponding authors). (2024). Promising use
of metformin in treating neurological disorders: biomarker-guided therapies.
Neural
Regeneration Research 2024 19:1045-1055.
Impact Factor: 6
Leung, J., Loan, A., Xu, Y.,
Yang, G., *Wang, J., and *Chan HM (*co-corresponding authors). (2024).
Reduction of glyoxalase 1 expression mediates methylmercury-induced fetal
premature neuronal differentiation.
Toxics, 12: 449.
Loan, A., Leung, J.W.,
Cook, D.P., KO, C., Vanderhyden, B.C., *Wang, J. and *Chan, H.M. (2023) (* co-corresponding authors) Prenatal low-dose methylmercury
exposure causes CREB-dependent premature neuronal differentiation and
autism-like behaviours in a rodent model.
iScience 26: 106093.
Impact factor: 6.1.
Syal, C., Wang, J. (2021) Biomarker-guided drug therapy:
personalized medicine for treating Alzheimer's disease.
Neural Regeneration Research 16: 2010-2011.
Kosaraju, J.#,
Seegobin, M.#, Gouveia, A., Syal1, C., Sarma, S.N., Lu, K.J. Ilin, J., He, L., Wondisford,
F.E., Lagace, D., De Repentigny, Y., Kothary, R., and Wang, J. (2020). (# co-first author). Metformin promotes CNS
remyelination and improves social interaction following focal demyelination
through CBP Ser436 phosphorylation.
Experimental Neurology 334:113454.
Impact Factor: 4.69
Yuan,
X., Wang, J., Man Chan, H. (2018) Sub-nanomolar
methylmercury exposures promote premature differentiation of murine embryonic
neural precursor in the expense of their proliferation.
Toxics 6:61
Impact Factor: 2.84 https://doi.org/10.3390/toxics6040061.
Ould-Brahim, F, Sarma, SN, Syal, C, Lu, K, Seegorbin, M,
Carter, A, Jeffers, M, Dore, C, Stanford, W, Corbett, D and Wang, J. (2018) Metformin Preconditioning of human iPSC-derived neural
stem cells promotes their engraftment and improve post-stroke regeneration and
recovery.
Stem Cells and Development 27: 1085-1096.
Impact Factor: 3.315
Syal, C*, Seegobin, M*, Sarma, SN, Gouveia, A, Hsu, K, Niibori, Y, He, L, Wondisford, FE,
Frankland,PW and Wang, J (* equal contribution) (2018). Ectopic expression of aPKC-mediated
phosphorylation in p300 modulates hippocampal neurogenesis, CREB binding and
fear memory differently with age.
Scientific Reports 8: 13489.
Impact Factor:4.122
doi: 10.1038/s41598-018-31657-2
Wang J (2014), "Multiple Facets of CBP in Forebrain Interneuron Development",
Neurogenesis 1, e29168
Tsui D, Voronova A, Gallagher D, Kaplan DR, Miller FD, Wang J. (2014 Jan 15) CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development.
Dev Biol 385(2):230-41.
Impact Factor: 3.9
Wang J: Weaver IC; Gauthier-Fisher A; Wang H; He L; Yeomans J; Wondisford F;
Kaplan DR; Miller FD. (2010 Jan 19), CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain.
Dev Cell 18(1):114-25
Impact Factor: 10.7
