Regenerative Medicine

News

	Researchers at The Ottawa Hospital awarded $3.9M from BioCanRx to develop new cancer immunotherapies April 9, 2025 - Researchers at The Ottawa Hospital have been awarded $3.9 million from BioCanRx to develop cutting-edge biotherapeutics that harness the immune system to fight cancer.
	Lab study provides new hope for newborns affected by rare lung disease March 21, 2025 - A team led by Drs. Bernard Thébaud, Sarah Wootton and Martin Kang found a way to give multiple doses of gene therapy for a deadly newborn lung disease, dramatically extending the lives of mice with this condition.
	Mouse study further supports role of muscle stem cells in Duchenne muscular dystrophy March 13, 2025 - “This study confirms that we’ll need to target both muscle fibres and muscle stem cells in order to treat this disease."
	ELEVATE seed grants help researchers at The Ottawa Hospital launch new ideas and collaborations March 3, 2025 - The grants, worth a total of $198,000, will advance research on muscle disease, stroke, ovarian cancer and scleroderma.
	ELEVATE seed grants to help researchers at The Ottawa Hospital improve prevention and care for kidney disease March 3, 2025 - The grants, worth a total of $200,000, focus on areas such as autoimmune kidney disease, mini-kidney models, kidney replacement education, and artificial intelligence to improve drug dosing.
	Why one gene has an outsized impact on neurodevelopmental disorders February 26, 2025 - “ADNP is a significant gene in neurodevelopmental disorders. With this new tool to study its function, we can work towards finding and testing new treatments."
	Could a preemie’s umbilical cord help repair their lungs? February 11, 2025 - “Our results suggest we could one day test whether cells from a preemie’s umbilical cord might prevent them from developing a chronic lung disease.”
	Researchers at The Ottawa Hospital awarded 16 CIHR grants worth more than $8 million February 3, 2025 - Researchers at The Ottawa Hospital are leading 16 new projects funded by the Canadian Institutes of Health Research (CIHR) through the most recent operating grant competition.
	Spinal muscular atrophy: Lab study shows importance of treating the liver to benefit a neuromuscular disorder January 7, 2025 - “Our study suggests that treating the liver may be just as important as treating the neuromuscular system in patients with SMA. This is important because some of the approved SMA therapies are better at reaching the liver than others.”
	Researchers discover postal code that allows proteins to hitch a ride around the body December 11, 2024 - Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver biochemical signals.

2024
November 14, 2024 -	New Canada Research Chairs to advance regenerative medicine, thrombosis and stroke research at The Ottawa Hospital
October 18, 2024 -	‘Stroke in a dish’ reveals new recipe for brain repair
September 16, 2024 -	$2.8M grant to support Canada-wide trial of cell therapy for preterm babies
September 10, 2024 -	Clinical trial to test muscular dystrophy therapy developed at The Ottawa Hospital
August 29, 2024 -	Lab study provides new hope for people with rare muscle disease
July 26, 2024 -	Lab discovery suggests possible new approach for treating progressive multiple sclerosis
July 23, 2024 -	New book chapter by our experts reveals secrets of the blood-brain barrier
July 18, 2024 -	Researchers at The Ottawa Hospital awarded 14 CIHR grants worth more than $10 million
June 28, 2024 -	Why 2007 was a memorable year for both The Ottawa Hospital and the Ottawa Senators
June 18, 2024 -	Researchers at The Ottawa Hospital awarded three grants for high risk, high reward and interdisciplinary research
May 24, 2024 -	Satellos Bioscience wins top company award and rings TSX bell
May 14, 2024 -	Study reveals molecular reason why arteries harden with age
May 6, 2024 -	The Ottawa Hospital’s new campus to become a hub for biotherapeutics research and manufacturing thanks to $59M grant
May 1, 2024 -	Two decades in the making — world-first trial aims to heal the lungs of preemies
April 23, 2024 -	Which cells have the greatest potential to repair the lungs of pre-term babies?
March 15, 2024 -	Are EVs travelling to injured lungs?
February 21, 2024 -	ELEVATE seed grants to help researchers at The Ottawa Hospital improve treatment for inflammatory and immune conditions
February 2, 2024 -	Researchers at The Ottawa Hospital awarded 9 CIHR grants worth more than $5 million
January 19, 2024 -	Tiny trailblazer: First baby treated in world-first trial for chronic lung disease
January 2, 2024 -	New scientist profile: Dr. Blair Gage uses stem cell biology to build blood vessels and develop new treatments
2023
December 20, 2023 -	Gene editing strategy shows promise in mice with spinal muscular atrophy
December 13, 2023 -	Life, death and DNA tethering: research explores how the eye responds to stress
November 9, 2023 -	Powering up the body’s EVs
September 28, 2023 -	Tiny Cells for Tiny Lungs
September 1, 2023 -	How do developing brain blood vessels and nerves link up? New study has some answers.
August 18, 2023 -	When the hangman isn't hanging: how cell death proteins might protect against ALS
July 21, 2023 -	Researchers at The Ottawa Hospital awarded 13 CIHR grants worth more than $7 million
July 12, 2023 -	Engineered lung tissue model reveals possible new treatment for lymphangioleiomyomatosis
July 12, 2023 -	With autism, the brain adapts to blood vessel problems by changing how it uses energy
June 8, 2023 -	Start-up company raises $55M to fuel development of new therapy for Duchenne muscular dystrophy
May 15, 2023 -	Novel stem cell drives ‘remarkable’ regeneration of tiny blood vessels in the lung
April 18, 2023 -	Molecule triggered by running could help with stroke recovery
March 23, 2023 -	First patient treated in world-first cell therapy trial to heal the lungs of preterm babies
March 16, 2023 -	Meet Dr. Manoj Lalu, the clinician-scientist bringing lab discoveries to patients every day
March 9, 2023 -	Prenatal exposure to low doses of methylmercury causes autism-like behaviors in mice
March 1, 2023 -	‘Cord blood cells are priceless for us’
February 28, 2023 -	Study could lead to new treatments for pulmonary hypertension and right heart failure
February 16, 2023 -	How a chronic lung disease in preterm babies also affects the brain
February 3, 2023 -	Researchers at The Ottawa Hospital awarded 15 CIHR grants worth more than $8.4 million
February 1, 2023 -	ELEVATE seed grants to help researchers at The Ottawa Hospital develop better treatments and improve patient care
January 19, 2023 -	Researchers at The Ottawa Hospital co-lead $39M Accelerating Clinical Trials (ACT) Consortium
January 19, 2023 -	Clinical trial will test promising cell therapy for septic shock
2022
November 2, 2022 -	Huge hope for our smallest patients
September 14, 2022 -	Soccer skills and stem cell science- Meet Dr. Bernard Thébaud
August 4, 2022 -	Hyaluronic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle
July 27, 2022 -	“Dream team” of researchers tackles leading cause of vision loss
July 21, 2022 -	Lab-grown “mini-kidneys” unlock secrets of a rare disease
July 20, 2022 -	Researchers at The Ottawa Hospital awarded 19 CIHR grants worth more than $12 million
July 13, 2022 -	Whole-body approach needed to treat neuromuscular disease SMA
June 22, 2022 -	Dr. Michael Rudnicki admitted as a Fellow of the Royal Society
June 17, 2022 -	First made-in-Canada CAR-T cell therapy for cancer shows promise in clinical trial
June 7, 2022 -	Do changes in brain metabolism play a role in autism? Prestigious grant to help researchers find out
May 12, 2022 -	Ottawa Hospital researchers awarded $1.85M from Stem Cell Network
April 28, 2022 -	Cancer cells break their own DNA to buy time to repair radiation damage
April 25, 2022 -	Meet brain and eye researcher Dr. Pierre Mattar
April 4, 2022 -	Researchers at The Ottawa Hospital awarded five grants for high risk, high reward and interdisciplinary research
March 30, 2022 -	Nano therapy for micro-preemies protects lungs, brain in lab study
March 9, 2022 -	Research on brain blood vessels could lead to new treatments for brain diseases
February 17, 2022 -	Tiny particles hold promise for treating acute and chronic lung disease
January 6, 2022 -	Study explores patient engagement in lab research
2021
November 19, 2021 -	Medicine’s future: living drugs
November 15, 2021 -	From baseball stats wiz to game-changing epigenetic scientist
November 12, 2021 -	Supercharging stem cells
November 4, 2021 -	Virtual care with remote monitoring catches drug errors and reduces patient pain
September 15, 2021 -	$2.4 M grant to help researchers develop gene and cell therapies for a leading cause of blindness
August 13, 2021 -	Nothing about me, without me: Engaging patients in clinical trials
August 10, 2021 -	Researchers at The Ottawa Hospital awarded eight grants worth $5 million from the Canadian Institutes of Health Research
June 2, 2021 -	Research unravels links between fasting, lifespan and muscle stem cells
May 31, 2021 -	Researchers at The Ottawa Hospital awarded three grants for high risk, high reward and interdisciplinary research
May 29, 2021 -	New mouse model could help with the development of treatments for nonalcoholic fatty liver disease
May 25, 2021 -	Biotherapeutics: the future of medicine
May 12, 2021 -	Stem cells go ‘all in’ to repair damaged muscles
April 30, 2021 -	Beyond the brain: how autism impacts the body
April 28, 2021 -	“Cell atlas” could shine light on lung problems in adults and premature babies
April 22, 2021 -	Experts on call: Stem cells, gene therapy and biotherapeutics
April 13, 2021 -	Grateful COVID-19 patient gives back by participating in research
April 5, 2021 -	Translational research grant could help to develop new immunotherapies for leukemia
March 12, 2021 -	The rise of point-of-care cell manufacturing
March 10, 2021 -	Researchers at The Ottawa Hospital awarded 17 CIHR grants worth $7.5 million
February 25, 2021 -	One small step for blood cancer patients, one giant step for Canadian cancer patients of all stripes
February 1, 2021 -	Experimental stem cell therapy a potential weapon against COVID-19
February 1, 2021 -	$1M investment fuels development of new therapies for Duchenne muscular dystrophy
January 27, 2021 -	Can a diabetes drug help repair damaged nerve insulation? Mouse study shows it might.
2020
November 6, 2020 -	Blueprint Excelerator helps move discoveries from the bench to the bedside
November 6, 2020 -	$1M grant to support manufacturing of COVID-19 treatments and vaccines at The Ottawa Hospital and uOttawa
October 26, 2020 -	Gene therapy for deadly newborn lung disease shows promise in mice
September 22, 2020 -	The Ottawa Hospital and uOttawa launch new cancer immunotherapy research projects with funding from BioCanRx
September 7, 2020 -	The Ottawa Hospital awarded six CIHR grants worth $2.6 million
July 13, 2020 -	Vascular development may be at risk in autism
July 10, 2020 -	Innovative clinical trial design breathes life into potential cell therapy for lung disease in preterm babies
June 25, 2020 -	The Ottawa Hospital awarded $4.7 million for COVID-19 research from the Canadian Institutes of Health Research
June 12, 2020 -	TOHAMO awards $1.2M for COVID-19 research projects
June 10, 2020 -	Can virtual care after surgery reduce patient returns to hospital? Research study now open in Ottawa
June 8, 2020 -	Using lab-grown human tissues to identify possible treatments
June 4, 2020 -	Creating a new mouse model to study COVID-19 lung disease
June 4, 2020 -	Studying the immune response of COVID-19 patients in the ICU
June 4, 2020 -	New mouse model to reveal insights into mild spinal muscular atrophy
June 4, 2020 -	Diabetes drug corrects some symptoms of Alzheimer’s disease in mice
June 3, 2020 -	New Frontiers in Research Fund supports trailblazing research on autism, Alzheimer’s, Parkinson’s
May 28, 2020 -	Experimental Stem Cell Therapy a Potential Weapon in COVID-19 Fight
May 21, 2020 -	COVID-19 research on cell therapy, drug screening and marginalized populations funded through Ontario’s Rapid Research Fund
May 14, 2020 -	Mysteries of cell fate unlocked with new measurement and modeling techniques
May 8, 2020 -	COVID-19 research moving at ‘lightning speed’, thanks to generous community support
April 29, 2020 -	Dr. Michael Rudnicki elected into the Royal Society
April 29, 2020 -	Researchers use lab-grown human tissues to understand secrets of COVID-19 infection, identify possible treatments
April 23, 2020 -	Harnessing stem cells and regenerative medicine to fight COVID-19
April 2, 2020 -	Researchers join the fight against COVID-19
March 4, 2020 -	Stem cells may heal lungs of premature babies
March 2, 2020 -	Could umbilical cord cell therapy help premature babies? Dr. Bernard Thébaud awarded $638,000 from Stem Cell Network for clinical trial
February 19, 2020 -	Cell therapy for premature babies: new lab study suggests wider treatment window may be possible
February 14, 2020 -	New neuromuscular network brings patients, scientists and clinicians together
February 3, 2020 -	The Ottawa Hospital awarded nine grants worth $5.6 million from Canadian Institutes of Health Research
January 15, 2020 -	To help protect research, experts agree on a definition of predatory publishing
January 15, 2020 -	New method can help labs around the world grow stem cells more efficiently
January 10, 2020 -	Nothing to sniff at: Screening platform identifies drugs that could fight the common cold
2019
November 13, 2019 -	Researchers awarded $1.6M to improve care for cardiovascular disease
October 22, 2019 -	How does a stem cell know what to be when it grows up?
October 2, 2019 -	Researchers reveal the circuitry regulating muscle stem cell function
September 27, 2019 -	Ottawa a “hotbed of patient partnerships in research”
September 13, 2019 -	A Canadian First: Ottawa orthopaedic researchers win top clinical research award three years running
September 10, 2019 -	Findings could improve quality of life for people with spinal muscular atrophy
August 14, 2019 -	The promise of CAR-T therapy for cancer: meta-analysis shows the big picture
July 26, 2019 -	The Ottawa Hospital awarded 13 grants worth $11.2 million from Canadian Institutes of Health Research
May 29, 2019 -	Researchers get $745,000 boost from NSERC
May 17, 2019 -	$950,000 to help develop stem cell treatments for septic shock, lung injury and muscle degeneration
May 1, 2019 -	Precision medicine approach for leukemia awarded $1.5M
April 24, 2019 -	Scientist investigates how two gene mutations contribute to autism
March 29, 2019 -	Breakthrough reveals how a stem cell decides between two fates
March 22, 2019 -	Clinicians at The Ottawa Hospital launch 14 innovative projects to improve health-care delivery, thanks to funding from TOHAMO and The Ottawa Hospital’s Research Institute
March 15, 2019 -	3D gel helps researchers find potential drugs for lung cancer, other diseases
March 1, 2019 -	Patients and clinical trial experts key to upcoming made-in-Canada CAR-T clinical trial
February 14, 2019 -	Researchers to advance science and improve health with new CIHR funding
January 31, 2019 -	Discovery points to innovative new way to treat Duchenne muscular dystrophy
January 30, 2019 -	Research shows how good heart growth turns bad
2018
October 23, 2018 -	Dr. William Stanford has been named The Ottawa Hospital’s Chrétien Researcher of the Year for his work on blood cancer and other diseases
October 22, 2018 -	New drug combination destroys chemo-resistant blood cancer
October 10, 2018 -	Brain Health Awareness Week: October 15-19
September 25, 2018 -	Trainee receives Canadian Medical Hall of Fame Award
August 30, 2018 -	Could leaky blood vessels be a target for treating migraines? Study opens up promising new area of research
August 22, 2018 -	Chaos in the nucleus: research on eye cells could provide insight into degenerative diseases
August 8, 2018 -	Diabetes drug could enhance stem cell treatment for stroke
July 20, 2018 -	$1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss
June 7, 2018 -	Top Research Papers from The Ottawa Hospital 2015-2017
May 30, 2018 -	Patent brings possible new heart failure treatment closer to reality
May 30, 2018 -	Stem cell researchers tackle muscle weakness in older people
April 30, 2018 -	Experimental stem cell therapy tested for rare lung disease
2017
June 23, 2017 -	Rehabilitation researchers win national awards for work on stem cells, mobility
2016
April 12, 2016 -	Ottawa researchers shine in SPOR funding announcement