Research Administration relies on an electronic web-based application called the Clinical Research Registration Form (CRRF) for tracking all research being conducted on site or by our researchers. All clinical research activity must be registered in the CRRF. Researchers/staff must access the CRRF through their own IRIS homepage. Please see the User Guide for Getting Started (coming soon) for details on how to obtain an IRIS account and access the IRIS system. For more information see the Process Map for the Clinical Research Registration Form (CRRF)
Who needs to register their research project in the CRRF?
- All TOH/OHRI personnel conducting research
- All UOHI/OHIRC personnel conducting research
All research projects conducted by the above personnel must be registered in the CRRF
- regardless of where the recruitment of participants, data collection and/or sample collection is taking place.
- regardless of the Board of Record (e.g. OHSN-REB or CTO Stream).
Is OHSN-REB review and approval required? (coming soon)
When can researchers begin their project?
New "green light" process for studies. An Institutional Approval Letter from OHRI and/or OHIRC is required prior to the initiation of the study.
The CRRF displays three sections, or "tabs": Ethics, Contracts, and Departmental Notifications.
Institutional Approval is an indication that you have satisfied all requirements for the three tabs, as applicable. Once approved, an Institutional Approval Letter will be issued, and the study may begin.
Tabs to be completed in the CRRF to obtain Institutional approval
| Ethics Application Stream |
Ethics Tab (Full or Registration) |
Contracts Tab | Notification Tab | Institutional Approval |
|---|---|---|---|---|
| OHSN-REB |
(Full) |
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Clinical Trials Ontario (CTO) (including OCREB) |
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|
(Registration only) |
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(Registration only) |
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Studies submitted under the CHEO and OHSN-REB Harmonization Agreement: |
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(Full) |
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(Registration only) |
French Translation Policy in Clinical Research
In keeping with The Ottawa Hospital (TOH) and the University of Ottawa Heart Institute (UOHI) policies on bilingualism, the Ottawa Health Science Network Research Ethics Boards expect that patient participants who are approached to participate in a clinical research project be able to receive recruitment materials, informed consent, and study documentation in the official language of their choice, English or French.
Translation applies to all research studies that involve patient participants at TOH and/or the UOHI, regardless of who the Board of Record (BOR) is (OHSN-REB, OCREB, CHEO REB or BOR through CTO Stream, etc.).
Please see the "Translation" tab of the OHSN-REB website for more detailed information.
CTO Stream Information
Instructions for CTO Stream Submissions and Registering your CTO project in the CRRF