Research News

Could a drug that controls appetite also treat schizophrenia and Alzheimer’s? Mouse studies show promise.
September 8, 2021 - Two recent studies suggest that the drug trodusquemine has the potential to treat symptoms of both schizophrenia and Alzheimer’s disease. This is because the drug targets an enzyme called PTP1B, which plays a role in both diseases
A conversation with Dr. Jess Fiedorowicz
August 18, 2021 - Dr. Jess Fiedorowicz is shining a light on mental health through his work and research at The Ottawa Hospital. Originally from the U.S., Dr. Fiedorowicz has been at our hospital since 2020 as the Head and Chief of the Department of Mental Health.
Study in mice reveals possible new target to treat schizophrenia
March 10, 2021 - The enzyme PTP1B may be a new target for treating schizophrenia, according to a study published in Neuropsychopharmacology.
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Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Albert, Paul
Senior Scientist
Mental health, Vascular cognitive impairment, Anxiety, Depression, Intellectual disabilities, Parkinson's, Schizophrenia, Stroke, Suicide Basic research, Epigenetics, Exercise, Gene expression, Translational research, Disease models, Epigenetics, Genetics, Imaging, Molecular and cellular biology, Optogenetics, Transgenic/knockout models
Chen, Hsiao-Huei
Senior Scientist
Aging, Autism, Dementia, Depression, Heart disease, Maternal and fetal health, Mental health, Tourette's, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease Disease models, Drug development, Gene expression, Neuro-stimulation, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Solmi, Marco
MD, PhD, Psychiatrist
Clinician Investigator
(Clinical Epidemiology)
Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews
Tiberi, Mario
Senior Scientist
Parkinson's, Schizophrenia, Stroke Basic research, Drug development, Molecular and cellular biology, Proteomics, Translational research