Ottawa Hospital Research Institute

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Diabetes

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of diabetes (type 1 and type 2) and develop better treatments. This page includes selected news stories about our diabetes research, links to researchers working in this area and related resources. Learn more below.

Research News

	New scientist profile: Dr. Blair Gage uses stem cell biology to build blood vessels and develop new treatments January 2, 2024 - As a self-proclaimed “cell therapist,” Dr. Blair Gage aims to understand what makes stem cells tick and then gently coax them to realize their full potential.
	Diabetes: innovative meta-analysis reveals best quality improvement strategies July 5, 2023 - Dr. Jeremy Grimshaw recently led an innovative Cochrane meta-analysis of 553 clinical trials including more than 400,000 participants around the world to determine the best quality improvement strategies for diabetes care.
	Tiny bits of blood vessel may warn of newborn complications November 4, 2021 - A study published in Biomarker Research co-led by Drs. Dylan Burger and Denice Feig found that extracellular vesicles may be able to predict newborn outcomes, at least in pregnant people with diabetes.
Show more news stories
	Can Type 2 diabetes be reversed? Research study available to Ottawa patients. January 31, 2020 - Can we put Type 2 diabetes into remission? The Ottawa Hospital is one of eight sites across the country where patients can participate in a study of a new approach to treat this chronic condition. Usually individuals with Type 2 diabetes start treatm
	Liver could be new target for type 1 diabetes research, treatments December 18, 2019 - Type 1 diabetes (T1D) is an autoimmune disease often diagnosed in children and young adults, but the disease process probably begins much earlier. Dr. Fraser Scott’s team conducted one of the first studies to identify very early defects in the liver
	Chance discovery linking diet to type 1 diabetes started whole new field of research October 22, 2018 - In the early 1980's, Dr. Fraser Scott was conducting nutritional studies on rats that were supposed to develop type 1 diabetes—except they didn't. He discovered that changing the diet of these diabetes-prone rodents had prevented the disease. Making
	How does type 1 diabetes start? New research implicates early metabolic defects in the pancreas September 6, 2018 - Type 1 diabetes (T1D) is often diagnosed in the teenage years, but the disease process probably starts much earlier. New research led by Dr. Fraser Scott shows that cellular stress is linked to decreased insulin and increased glucagon production in t
	$1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss July 20, 2018 - Four research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $1.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). Their projects will advance sci
	New blood sugar monitoring a game-changer for pregnant women with type 1 diabetes October 24, 2017 - Fifteen women at The Ottawa Hospital took part in an international clinical trial that could change the way mothers with type 1 diabetes monitor their blood sugar levels. Mothers with this condition have a higher risk of having children with health c
	The Ottawa Hospital awarded 18 research grants from the Canadian Institutes of Health Research, worth $10.7 million May 19, 2017 - Eighteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded nearly $11 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a suc

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Austin, Michael MD, FRCPC, DRCPSC (PTM)	Clinician Investigator (Acute Care Research)	Asthma, Cardiac arrest, Chronic obstructive pulmonary disease, Diabetes, Pain, Population health, Stroke	Clinical decision rules, Clinical trials, Cluster randomized trials, Cohort studies, Critical care, Emergency medicine, Palliative care, Risk assessment
Burger, Dylan PhD	Senior Scientist (Inflammation and Chronic Disease)	Aging, Diabetes, Heart disease, Hypertension, Kidney disease, Maternal and fetal health, Obesity, Thrombosis / thromboembolism, Type 1 diabetes, Vascular cognitive impairment, Vascular, heart and metabolic disease	Basic research, Biomarkers, Disease models, Exercise, Extracellular vesicles / exosomes, Imaging, Model organisms, Molecular and cellular biology, Pharmacology, Proteomics, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Burns, Kevin MD CM, FRCPC	Senior Scientist (Inflammation and Chronic Disease)	Diabetes, Kidney disease, Vascular, heart and metabolic disease	Basic research, Biomarkers, Cell therapy, Clinical research, Disease models, Extracellular vesicles / exosomes, Gene expression, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Chen, Hsiao-Huei PhD	Senior Scientist (Neuroscience)	Aging, Autism, Dementia, Depression, Heart disease, Maternal and fetal health, Mental health, Tourette's, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease	Disease models, Drug development, Gene expression, Neuro-stimulation, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Dargel, Aroldo M.D., Ph.D.	Associate Scientist (Neuroscience)	Anxiety, Bipolar, Dementia, Depression, Diabetes, Hypertension, Mental health, Obesity, Population health, Suicide, Vascular, heart and metabolic disease	Artificial intelligence and data science, Behaviour, Big data, Biomarkers, Biostatistics, Clinical research, Clinical trials, Digital and mobile health, Epidemiology, Health technology, Prevention, Psychology, Quality Improvement, Rapid reviews, Systematic reviews, Translational research
Druce, Irena MD, FRCPC, MSc	Clinician Investigator (Inflammation and Chronic Disease)	Diabetes, Health equity	Cancer immunotherapy, Health promotion, Translational research
El-Chaar, Darine MD, FRCSC, Msc	Scientist (Inflammation and Chronic Disease)	Autoimmune disease, COVID-19, Diabetes, Infectious disease, Inflammatory bowel syndrome, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
Gage, Blair PhD	Scientist (Regenerative Medicine)	Bleeding disorders, Diabetes, Liver cancer, Liver disease, Vascular, heart and metabolic disease	Basic research, Bioinformatics, Cell therapy, Disease models, Gene expression, Gene therapy, Genetics, Genomics, Model organisms, Molecular and cellular biology, Regenerative medicine, Stem cells, Translational research, Transplantation
Hiremath, Swapnil MD, MPH, FASN	Associate Scientist (Inflammation and Chronic Disease)	Diabetes, Health in older peoples, Heart disease, Hypertension, Kidney disease, Population health, Vascular, heart and metabolic disease	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health services research, Imaging, Pharmacology, Pragmatic trials, Public health, Quality Improvement, Systematic reviews
Kennedy, Christopher PhD	Senior Scientist (Inflammation and Chronic Disease)	Diabetes, Hypertension, Kidney disease	Molecular and cellular biology
Manuel, Douglas MD, MSc, FRCPC	Senior Scientist (Methodological and Implementation Research)	Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
McBurney, Michael PhD	Program Director and Senior Scientist Emeritus (Cancer Research)	Aging, Diabetes, Cancer	Molecular and cellular biology, Transgenic/knockout models, Basic research
Presseau, Justin PhD	Senior Scientist (Methodological and Implementation Research)	Chronic pain, COVID-19, Diabetes, Health equity, Hepatitis C, Immigrant and refugee health, Inflammatory bowel syndrome, Retinal disease, Vision	Artificial intelligence and data science, Health services research, Patient engagement, Psychometrics, Public health, Qualitative methods, Quality Improvement, Rapid reviews, Transfusions, Transplantation, Behaviour, Psychology, Health professional behaviour change, Knowledge translation and implementation research, Health promotion, Cluster randomized trials, Surveys
Sorisky, Alexander MD, CM, FRCPC	Program Director and Senior Scientist Emeritus (Inflammation and Chronic Disease)	Obesity, Diabetes, Heart disease	Basic research, Molecular and cellular biology
Thavorn, Kednapa BPharm, MPharm, PhD	Senior Scientist (Methodological and Implementation Research)	Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision	Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews

Related Resources

The Ottawa Hospital’s Diabetes, Obesity, Metabolism and Endocrinology (DOME) Research Centre

The Ottawa Hospital’s Foustanellas Endocrine and Diabetes Centre

Search for clinical trials at The Ottawa Hospital related to this disease or condition.