Ottawa Hospital Research Institute

Clinical trials

The Ottawa Hospital is a leader in conducting clinical trials to determine the safety and effectiveness of treatments, devices and procedures. This page includes selected news stories about our clinical trials, links to researchers doing clinical trials and related resources. You can also use this tool to search for clinical trials that are actively recruiting patients at The Ottawa Hospital.

Research News

	Non-invasive brain stimulation shows promise in reducing psychological distress in advanced illness April 8, 2024 - A small clinical trial at The Ottawa Hospital and Bruyère has shown for the first time that repetitive transcranial magnetic stimulation (rTMS) holds promise as a treatment for psychological distress in people with advanced illness.
	Randy McElligott’s unusual reaction to his cancer diagnosis February 27, 2024 - Access to clinical trials is key for patients like Randy. “It means the world to have access to this type of care. And if I can help other patients, what could be better?”
	Reinvigorating immunotherapy: clinical trial provides new hope for lung cancer patients February 23, 2024 - The Ottawa Hospital played a key role in an international clinical trial that is providing new hope for people with advanced non-small cell lung cancer (NSCLC).
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	Tiny trailblazer: First baby treated in world-first trial for chronic lung disease January 19, 2024 - Emmy Cogan was the first baby treated in a world-first clinical trial of a cell therapy for bronchopulmonary dysplasia.
	Immunotherapy improves survival with mesothelioma lung cancer January 4, 2024 - An international clinical trial published in The Lancet shows that immunotherapy improves survival in people with an aggressive type of lung cancer called pleural mesothelioma.
	Undiagnosed asthma and COPD a burden for patients, even in early stages December 6, 2023 - Adults with undiagnosed COPD or asthma have worse quality of life, greater healthcare use and are less productive at work than healthy adults.
	Capturing immunotherapy response in a blood drop October 26, 2023 - A clinical trial published in Nature Medicine suggests that using a “liquid biopsy” to measure tiny bits of tumour DNA in blood could determine if immunotherapy drugs are working in patients with advanced non-small cell lung cancer.
	Global research trial for ICH stroke a major step forward for patients October 25, 2023 - Dr. Dar Dowlatshahi is leading the Canadian site of the research trial and hopes it will change the way we treat the deadliest and least treatable form of stroke.
	New scientist profile: Dr. Deborah Zimmerman is committed to improving quality of life for patients on hemodialysis October 13, 2023 - Dr. Zimmerman wonders whether starting some patients on hemodialysis more gradually at two days a week while they still have some kidney function would give them a bit more time to enjoy their regular activities. There has been very little research i
	Tiny Cells for Tiny Lungs September 28, 2023 - “Stem cells used to be something that were grown in a petri dish. They are now game-changing therapies with live-saving potential for even the tiniest of patients.”
	Meet Dr. Edward Clark, The Ottawa Hospital’s new Jindal Research Chair for the Prevention of Kidney Disease September 28, 2023 - As The Ottawa Hospital’s new Jindal Chair for Kidney Disease Prevention, Dr. Clark will be able to accelerate his research, which aims to help more critically ill patients survive acute kidney injury, and recover enough kidney function to avoid dialy
	Am I still a safe driver? This 5-min test could start the conversation August 18, 2023 - A five-minute questionnaire could help doctors start a conversation with older adults who have medical conditions that may affect their ability to drive.
	Space travel alters gene expression in white blood cells, weakening the immune system June 22, 2023 - The expression of (mostly protein-coding) genes in white blood cells changes rapidly when astronauts reach the International Space Station
	2,000 Ottawa participants recruited to breast cancer screening study May 26, 2023 - The Ottawa site of the Tomosynthesis Mammographic Imaging Screening Trial (TMIST) recently reached its enrollment goal of 2,000 participants. Led by Dr. Jean Seely, the Ottawa site first opened in 2017.
	How a heart attack drug is revolutionizing stroke treatment May 11, 2023 - A clot-busting drug developed to treat heart attack is now being used as a standard treatment for acute ischemic stroke, thanks in large part to research at The Ottawa Hospital.
	Sex of blood donor has no effect on recipient survival April 12, 2023 - A large clinical trial of more than 8,700 patients published in the New England Journal of Medicine concluded that the sex of a donor has no effect on the survival of recipients of red blood cell transfusions.
	Exercise before surgery? This cancer survivor is a believer April 4, 2023 - Find out why he credits a “prehab” study for his quick recovery
	First patient treated in world-first cell therapy trial to heal the lungs of preterm babies March 23, 2023 - Researchers have treated the first patient in an innovative clinical trial of a cell therapy that aims to prevent very premature babies from developing a chronic lung disease called bronchopulmonary dysplasia (BPD). This is the first trial of its kin
	Moving the needle forward on sepsis research with a world-first clinical trial March 16, 2023 - The search for the silver bullet for sepsis has been decades in the making. However, The Ottawa Hospital is taking a big step forward in the next phase of a world-first clinical trial using stem cells in patients with septic shock.
	Meet Dr. Lauralyn McIntyre — sepsis researcher and clinician extraordinaire March 16, 2023 - Dr. Lauralyn McIntyre’s path to The Ottawa Hospital wasn’t necessarily a direct one — it took her all over Ontario and out west to the mountains — but she couldn’t do her groundbreaking sepsis research anywhere else, or with any other team.
	“Every day is a struggle for me”: A new study is evaluating the effectiveness of a digital app in treating people suffering from long COVID February 28, 2023 - Researchers at The Ottawa Hospital and the Ottawa Hospital Research Institute are studying the effectiveness of a digital health platform in helping people recover from post COVID-19 condition, or long COVID.
	Researchers at The Ottawa Hospital co-lead $39M Accelerating Clinical Trials (ACT) Consortium January 19, 2023 - The new Accelerating Clinical Trials (ACT) Consortium, co-led by The Ottawa Hospital, aims to transform Canada’s clinical trials landscape by removing barriers, streamlining approvals, enhancing support and facilitating the engagement and participati
	Made-in-Canada approach enhancing access to groundbreaking CAR-T cancer therapy January 19, 2023 - Researchers at The Ottawa Hospital are partnering with colleagues across the country to expand access to new technology that turns patients’ immune cells into super-charged cancer-killers.
	Clinical trial will test promising cell therapy for septic shock January 19, 2023 - Dr. Lauralyn McIntyre was awarded $1.6 million from the Canadian Institutes of Health Research Clinical Trials Fund to conduct a Phase II clinical trial of mesenchymal stem cells (MSCs) in patients with septic shock.
	When a heart won’t start, some defibrillation strategies work better than others January 11, 2023 - A randomized controlled trial published in the New England Journal of Medicine found that two different defibrillation strategies were associated with increased survival among out-of-hospital cardiac arrest patients whose hearts didn’t start after st
	Spirometry can’t catch all asthma diagnoses January 4, 2023 - A study led by Dr. Shawn Aaron suggests that asthma and eosinophilic bronchitis may be undiagnosed in a significant number of people who have symptoms, but have normal spirometry lung function tests.
	Intravenous vitamin C treatment does not help sepsis patients December 14, 2022 - A randomized controlled trial published in the New England Journal of Medicine has quashed the theory that intravenous vitamin C could prevent death and organ damage in patients with sepsis.
	Canadian-Led Immunotherapies in Cancer (CLIC) program inspires innovative CAR-T trial in Denmark December 8, 2022 - CAR-T therapy is a groundbreaking cancer treatment that involves genetically engineering a patient’s own immune cells to attack their cancer. While this therapy is commercially available in many countries, cancer researchers are also developing their
	Bench to bedside: the quest to prevent cancer from coming back after surgery October 20, 2022 - Researchers at The Ottawa Hospital have made another important step forward in their quest to find innovative ways to stop cancer from coming back after surgery. While surgery often provides the best option for removing all or most of a tumour, resea
	Novel DNA-targeting drug shows activity in patients with breast, ovarian cancer October 13, 2022 - A clinical trial led by Dr. John Hilton shows that a novel drug called CX-5461 is active in patients with advanced solid cancers with DNA repair deficiencies. The phase I trial enrolled 40 patients at The Ottawa Hospital and two other centres.
	Does “prehab” before surgery improve patient outcomes? Pilot sets the stage for national trial October 5, 2022 - A home-based prehabilitation or “prehab” program designed to help older adults with frailty recover from cancer surgery has shown promise in a randomized pilot trial, particularly for patients who had a high level of adherence to the program.
	Ottawa-area residents invited to participate in multivalent COVID-19 vaccine trial October 5, 2022 - Healthy adults are invited to participate in a clinical trial at The Ottawa Hospital to test a multivalent coronavirus vaccine candidate developed by VBI Vaccines Inc., a biotechnology company with Ottawa-based research and development facilities.
	A conversation with stem cell pioneer Dr. Harold Atkins October 4, 2022 - When Dr. Harry Atkins was young, he wanted to be an architect. Everything changed with one high school biology project, and now Dr. Atkins is pioneering the use of stem cells to reprogram people’s immune systems.
	Soccer skills and stem cell science- Meet Dr. Bernard Thébaud September 14, 2022 - Every day, Dr. Bernard Thébaud creates futures for Ottawa’s youngest community members. As a senior scientist with the Ottawa Hospital Research Institute, and as a neonatologist with the Children’s Hospital of Eastern Ontario (CHEO), Dr. Thé
	Arginine supplement prevents cancer spread after surgery in mice, but more research in humans is required September 1, 2022 - Two new papers from Dr. Rebecca Auer’s group are shedding light on how cancer spreads after surgery and how we might stop it.
	Dr. Marc Carrier recognized as one of top blood clot researchers in Canada July 13, 2022 - Dr. Marc Carrier has received a major honour recognizing his outstanding contributions to advancing blood and blood vessel care in both in Canada and around the world.
	Breakthrough could revolutionize stroke treatment June 29, 2022 - In the largest stroke clinical trial ever run in Canada, researchers have shown Tenecteplase (TNK), a safe, well tolerated drug, commonly used as a clot buster for heart attacks, is an effective treatment for acute ischemic stroke, a stroke caused by
	First made-in-Canada CAR-T cell therapy for cancer shows promise in clinical trial June 17, 2022 - More than a dozen people with cancer who had exhausted all treatment options are alive and cancer-free today thanks to a pioneering Canadian clinical trial of a highly personalized kind of immunotherapy.
	New scientist profile: Dr. David Massicotte-Azarniouch aims to improve care for rare kidney diseases May 20, 2022 - As a nephrologist specializing in glomerular diseases, Dr. David Massicotte-Azarniouch embraces the challenge of helping patients whose kidneys are being attacked by their own immune systems.
	Meet the award-winning team behind our cancer clinical trials May 18, 2022 - What does it take to run a world-class cancer clinical trials program that tests new therapies and gives patients hope, time, and quality of life? At The Ottawa Hospital’s Oncology Clinical Trials Office, it takes a large and dedicated team of 60 sta
	Ottawa Hospital researchers awarded $1.85M from Stem Cell Network May 12, 2022 - Four research teams at The Ottawa Hospital have been awarded a total of $1.85 million to harness stem cells and regenerative medicine to develop new therapies for septic shock, bone and joint conditions, and newborn lung damage, while also advancing
	Ottawa researchers contribute to three important studies shaping COVID-19 care April 28, 2022 - Researchers from The Ottawa Hospital continue to play a key role in influential COVID-19 research, with three studies recently published in top-tier journals.
	Researchers at The Ottawa Hospital awarded five grants for high risk, high reward and interdisciplinary research April 4, 2022 - The New Frontiers in Research Fund (NFRF) 2021 Exploration competition has awarded $25 million to support 102 research teams across Canada that bring diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
	A “smorgasbord” of cancer research, treatment, and life philosophy March 18, 2022 - Dr. Mark Clemons’ keen sense of humour and sharp wit have earned him an enduring and respected reputation among cancer patients at The Ottawa Hospital, where he is a medical oncologist. His patients regularly comment on the positive difference his un
	New scientist profile: Dr. Edward Clark aims to improve kidney health for hospitalized patients March 17, 2022 - As a nephrologist who sees patients in the ICU, Dr. Edward (Ted) Clark knows kidneys can often stop working when someone is critically ill.
	A patient’s dying wish to move medical science forward December 9, 2021 - Despite battling breast cancer, Paula Helmer found a driving ambition and raised her voice in support of clinical trials.
	Cannabis for cancer-related symptoms: actively recruiting patients for clinical trial December 6, 2021 - This new study will research if cannabis oils are effective in treating symptoms related to your cancer or cancer treatment.
	Making every blood transfusion count November 12, 2021 - Dr. Dean Fergusson is receiving The Ottawa Hospital’s Grimes Career Achievement Award for trailblazing research that is saving lives and blood around the world
	Virtual care with remote monitoring catches drug errors and reduces patient pain November 4, 2021 - The use of take-home technology by patients following non-elective surgery resulted in significantly greater detection and correction of drug errors, and reduced pain, according to a study published in The BMJ.
	Help us advance Respiratory Syncytial Virus (RSV) vaccine research in older adults. October 6, 2021 - The Ottawa Hospital is participating in an RSV vaccine research trial and is looking for volunteers aged 60 years and older.
	Major study finds convalescent plasma doesn’t help seriously ill COVID-19 patients September 29, 2021 - A randomized controlled trial involving more than 900 patients has found that convalescent plasma does not reduce the risk of intubation or death for COVID-19 patients.
	Treatment while waiting for surgery for breast cancer - can it improve surgical outcomes? June 23, 2021 - Drs. Angel Arnaout and Arif Awan are leading a clinical trial to determine if an experimental treatment can slow down the growth and spread of early stage breast cancer while activating the patient’s immune system before surgery
	Melding mind and machine: Ottawa trial could lead to new technologies to help people with paralysis June 16, 2021 - Researchers at The Ottawa Hospital and the University of Ottawa are launching a world-first clinical trial that could lead to a new kind of brain computer interface, paving the way for advanced technologies to help people with paralysis.
	New Canada-Wide Research to Study Mixing-and-Matching COVID-19 vaccines May 20, 2021 - The Government of Canada, through the COVID-19 Immunity Task Force (CITF) and the Vaccine Surveillance Reference Group (VSRG), is supporting a new nation-wide study that will look at the effects of ‘mixing-and-matching’ approved COVID-19 vaccines in
	Hold the ice: study shows no benefit during kidney cancer surgery May 19, 2021 - A clinical trial shows that contrary to popular belief, renal hypothermia doesn’t actually improve kidney function after kidney cancer surgery.
	New Scientist profile: Dr. Miriam Kimpton aims to prevent blood clots in patients with rare blood cancer April 30, 2021 - Dr. Miriam Kimpton’s research centers on myeloproliferative neoplasms, a rare form of chronic blood cancer
	Cancer clinical trial team and investigator receive major national honours April 29, 2021 - A group from The Ottawa Hospital Cancer Program has received the Investigational New Drug Program Team Award from the Canadian Cancer Trials Group for the sixth time in 10 years.
	Personalized approach reduces nausea in breast cancer patients April 15, 2021 - Cancer chemotherapy often causes nausea and vomiting, but a new clinical trial shows that a personalized approach can help. The trial, led by Dr. Mark Clemons, used a calculator his team developed to identify breast cancer patients with a high risk o
	Grateful COVID-19 patient gives back by participating in research April 13, 2021 - Sharon Charlebois doesn’t remember much about the 25 days she spent at The Ottawa Hospital fighting a severe case of COVID-19 in January 2021. Now that she’s recovering at home with her husband, some memories come back to her in flashes.
	Giving every COVID-19 patient the chance to participate in research March 17, 2021 - Most patients admitted to The Ottawa Hospital with COVID-19 have probably met Irene Watpool or Rebecca Porteous, even if they don’t remember it. Since the beginning of the pandemic, Irene and Rebecca have been on the front lines explaining all the av
	New scientist profile: Dr. Darine El-Chaâr aims to help pregnant parents and their babies March 10, 2021 - Dr. Darine El-Chaâr’s research focuses on three areas: increasing breast/chestfeeding among patients with diabetes, cannabis use in pregnancy, and COVID-19 in pregnancy.
	Blood thinners help keep hospitalized COVID-19 patients out of ICU February 17, 2021 - Full-dose blood thinners reduced the need for mechanical ventilation and transfer to the ICU in moderately ill patients hospitalized with COVID-19, according to interim results from an international clinical trial.
	New scientist profile: Dr. Tzu-Fei Wang aims to guide blood clot care for cancer patients February 17, 2021 - When hematologist Dr. Tzu-Fei Wang is deciding on the best way to treat a patient’s blood clot, she’ll ask whether they are taking any other medications. A quick check of an online database confirms whether these medications interact poorly with any
	Experimental stem cell therapy a potential weapon against COVID-19 February 1, 2021 - Drs. Duncan Stewart, Shane English, Dean Fergusson and colleagues have launched a clinical trial to test MSCs in people with severe COVID-19.
	World-first clinical trial aims to protect cancer patients from COVID-19 December 9, 2020 - Our researchers are leading the way in a world-first clinical trial to protect vulnerable cancer patients during the COVID-19 pandemic.
	The Ottawa Hospital contributes to ‘a beautiful evolution’ in HIV research and care December 4, 2020 - In honour of World AIDS day, we take a look back at how The Ottawa Hospital played a major role in caring for patients with HIV, how it continues to lead life-saving research, and how it is transforming how HIV is managed today.
	Breast cancer patients benefit from Ottawa-based study December 3, 2020 - There is such deep love in Gina Mertikas-Lavictoire’s eyes when she looks at her three young children. But there is something else, too: fear. Fear that one or even both of her daughters will develop the same aggressive breast cancer she’s had. So, w
	Bone-modulating drugs can be given less often during cancer treatment, reducing side-effects and saving time and money November 28, 2020 - When cancer spreads to the bones, it can cause pain, reduce mobility and increase the risk of fractures. Bone modulating drugs can help, but a new study suggests that to maximize the value of these drugs, it may be better to give them less often.
	Drug can treat Parkinson’s-related drooling, study shows October 21, 2020 - An Ontario study led by Dr. Tiago Mestre provides the first longer-term evidence that glycopyrrolate can reduce drooling associated with Parkinson’s disease.
	Fewer hospital visits, safer care, less cost: study changing breast cancer treatment around the world October 15, 2020 - A new study published in Annals of Oncology shows that a drug commonly used to prevent infections in breast cancer patients can safely be given less often, meaning fewer hospital visits, fewer side effects and reduced treatment costs.
	Hold the blood: world-first clinical trial could cut transfusions nearly in half for blood cancer patients September 23, 2020 - Regular red blood cell transfusions are a reality of life for many people with blood cancer. But now, a world-first clinical trial published in the Journal of Clinical Oncology has found that blood cancer patients don’t need nearly as many blood tran
	Canadian study compares COVID-19 spit test to traditional swab test September 8, 2020 - A new study led by researchers at The Ottawa Hospital, University of Ottawa and the Public Health Agency of Canada’s National Microbiology Laboratory shows that a Canadian-made spit test can detect the COVID-19 virus.
	Innovative clinical trial design breathes life into potential cell therapy for lung disease in preterm babies July 10, 2020 - When it comes to developing medical treatments, it is a long, challenging and expensive road from the research lab to the clinic.Most Canadians give little thought to what goes into the healthcare we receive – we’re happy to get good care when and wh
	Protecting cancer patients from COVID-19 July 8, 2020 - In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations – cancer patients.
	Hyperbaric oxygen therapy for COVID pneumonia June 26, 2020 - Astudy led by Dr. Sylvain Boet will test if hyperbaric oxygen therapy may be able to help some people with COVID-19 pneumonia.
	The Ottawa Hospital awarded $4.7 million for COVID-19 research from the Canadian Institutes of Health Research June 25, 2020 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $4.7 million from the Canadian Institutes of Health Research (CIHR) for four research projects that could transform our understanding of COVID-19 and lead
	Can virtual care after surgery reduce patient returns to hospital? Research study now open in Ottawa June 10, 2020 - COVID-19 has accelerated the adoption of all kinds of virtual health care, from phone and video appointments to tools that monitor symptoms remotely. The Ottawa Hospital continues to be at the forefront of this trend with the launch of an innovative
	Experimental Stem Cell Therapy a Potential Weapon in COVID-19 Fight May 28, 2020 - Ottawa-based researchers pivot at lightning speed to launch study on treating related respiratory failure
	New scientist profile: Dr. Robert Fahed wants more people to benefit from life-saving stroke therapy May 27, 2020 - Dr. Robert Fahed saves lives by pulling blood clots out of the brains of stroke patients. This minimally invasive procedure called thrombectomy has revolutionized stroke care, and Dr. Fahed wants as many patients as possible to benefit. However, he’s
	COVID-19 research on cell therapy, drug screening and marginalized populations funded through Ontario’s Rapid Research Fund May 21, 2020 - Researchers from The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded almost $2 million from Ontario’s COVID-19 Rapid Research Fund for three research projects that could help in the fight against the virus. These three pr
	Thanking the heroes behind clinical trials May 20, 2020 - COVID-19 has put a special focus on the importance of clinical trials in finding ways to diagnose, treat and prevent this new infection, but clinical trials have always been essential to improving care and saving lives at The Ottawa Hospital. Six cli
	Harnessing stem cells and regenerative medicine to fight COVID-19 April 23, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa have been awarded $490,000 from the Stem Cell Network for two research projects that could help in the fight against COVID-19. These peer-reviewed grants are part of an overall investm
	Researchers join the fight against COVID-19 April 2, 2020 - As hospitals and communities band together to fight COVID-19, researchers at The Ottawa Hospital are harnessing their unique expertise and resources to help.
	Stem cells may heal lungs of premature babies March 4, 2020 - Premature babies need extra oxygen and mechanical intervention to breathe but this can damage their lungs, causing a chronic lung disease. A stem cell treatment soon to be tested in clinical trials at The Ottawa Hospital may help heal the lungs of pr
	Could umbilical cord cell therapy help premature babies? Dr. Bernard Thébaud awarded $638,000 from Stem Cell Network for clinical trial March 2, 2020 - Dr. Bernard Thébaud and colleagues received $638,000 from the Stem Cell Network with in-kind matching funds from MDTB Cells GmbH to conduct a phase 1 clinical trial of umbilical cord cell therapy for premature babies.
	Could biotherapeutics be the next revolution in cancer treatment? February 20, 2020 - From helping the body’s own immune system better detect and fight cancer, to treating cancer with immune cells, viruses and vaccines, The Ottawa Hospital is conducting cutting-edge research that could transform cancer care right here at home and arou
	The Ottawa Hospital awarded nine grants worth $5.6 million from Canadian Institutes of Health Research February 3, 2020 - How can we treat depression when nothing else is working? How can heart growth be both good and bad? How can we increase patient participation in clinical trials? These are just a few of the big questions that researchers at The Ottawa Hospital will
	Can Type 2 diabetes be reversed? Research study available to Ottawa patients. January 31, 2020 - Can we put Type 2 diabetes into remission? The Ottawa Hospital is one of eight sites across the country where patients can participate in a study of a new approach to treat this chronic condition. Usually individuals with Type 2 diabetes start treatm
	Intravenous drugs can often rapidly restore normal heart rhythm without sedation, shocks January 30, 2020 - A study published in The Lancet found that two ways of quickly restoring normal heart rhythm in patients with acute atrial fibrillation in the emergency department are equally safe and effective.
	Curious about cancer, research and clinical trials? Join us on November 2, 2019 for "Cancer: Piecing the Puzzle Together" October 19, 2019 - This free event is organized by the Canadian Cancer Research Alliance in collaboration with The Ottawa Hospital and other partners. It will be of interest to cancer patients, survivors, their families and others affected by or interested in the disea
	Ottawa researcher plays key role in $53-million Alzheimer’s research project September 24, 2019 - Dr. Monica Taljaard is playing a major role in a $53-million project funded by the U.S. National Institute of Aging to improve health care and quality of life for people living with Alzheimer’s disease, as well as for their caregivers.
	A Canadian First: Ottawa orthopaedic researchers win top clinical research award three years running September 13, 2019 - For the third year in a row, researchers from the Division of Orthopaedic Surgery have won The Canadian Orthopedic Foundation’s top clinical research award, worth $20,000.
	Dr. Hanns Lochmüller receives Canada Research Chair in Neuromuscular Genomics and Health July 8, 2019 - Dr. Hanns Lochmüller has been awarded a prestigious Tier 1 Canada Research Chair (CRC) through the University of Ottawa Faculty of Medicine.
	Common supplement being tested as potential treatment for progressive MS June 27, 2019 - Lipoic acid (LA), a natural antioxidant, has shown promising results in a small pilot trial in helping people with multiple sclerosis (MS) walk faster and preventing brain atrophy.
	Golfer credits Ottawa study for quick recovery after lung cancer surgery June 4, 2019 - Marie Lapointe took part in a pilot study at The Ottawa Hospital aimed at testing whether a home-based exercise program could help older people better prepare for surgery
	Clinical trials offer strong foundation for better patient care May 16, 2019 - Clinical trials are an important step toward developing new treatments and learning more about diseases and conditions. In honour of International Clinical Trials Day, read how some of the researchers at The Ottawa Hospital are making huge contribut
	New scientist profile: Dr. Hanns Lochmüller investigates rare neuromuscular disorders March 15, 2019 - Dr. Hanns Lochmüller, a neurologist and senior scientist recently recruited to CHEO Research Institute from the U.K., has now also been appointed as an associate scientist in the Neuroscience Program at the Ottawa Hospital Research Institute.
	Can behavioural science help reduce unnecessary medical tests? March 11, 2019 - Up to one in three medical tests and treatments in Canada are not needed, and can expose patients to harm, stress, and longer wait times.
	Preventing blood clots from coming back March 1, 2019 - Dr. Marc Carrier and his colleagues pooled data from more than 22,000 patients around the world to compare the effectiveness of multiple blood thinners to treat venous thromboembolism.
	Patients and clinical trial experts key to upcoming made-in-Canada CAR-T clinical trial March 1, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa are known around the world for their expertise in designing and leading clinical trials, and they're now applying this knowledge to create a made-in-Canada approach for CAR-T cell cl
	Research could help people with cancer avoid life-threatening blood clots February 20, 2019 - In September 2018, Harold Black had trouble catching his breath while singing in his church choir. It turned out he had a life-threatening blood clot – a condition that is more common in people with cancer, like Harold. Today, people with cancer have
	TMIST - MAC.22 January 17, 2019 - If you are a woman aged 45 to 74 who is planning to get a routine screening mammogram then you are eligible for this trial. Please ask your doctor to fax a request to The Ottawa Hospital Breast Imaging Booking office at 613-761-4405, clearly indicat
	Drug dramatically reduces risk of dangerous blood clots in cancer patients December 4, 2018 - A Canadian clinical trial published in the New England Journal of Medicine provides the first approach for safely preventing blood clots (or venous thromboembolism) in people with cancer. About half of people newly diagnosed with a solid cancer coul
	Engaging patients in research every step of the way November 28, 2018 - CMAJ's new supplement on engaging patients in health research features commentaries led by Drs. Dean Fergusson, Simon Hatcher and Christian Vaillancourt, as well as 14 other teams affiliated with Ontario’s SPOR SUPPORT Unit (OSSU). As co-Scientific D
	Study shows which stroke patients benefit most from clot-busting drug October 25, 2018 - Dr. Dar Dowlatshahi co-authored an international study that could help predict which ischemic stroke patients would benefit the most from a clot-busting drug. This kind of stroke can be treated with the drug alteplase or by running a long thin tube t
	Made-in-Ottawa rule helps patients with neck injuries in the emergency department October 17, 2018 - A study led by Dr. Ian Stiell found that triage nurses in the emergency department can safely use a made-in-Ottawa rule to make wait times shorter and more comfortable for patients who have neck pain after a fall or car collision. Due to a very small
	Researchers awarded $1.7 M to tackle stroke and heart attack from multiple angles October 2, 2018 - Five groups from The Ottawa Hospital, affiliated with the University of Ottawa, were successful in the Heart and Stroke Foundation's recent grant competition. Drs. Dar Dowlatshahi, Tim Ramsay and Elizabeth Rochon were awarded $290,000* to test whethe
	World’s largest transfusion study in cardiac surgery changes practice globally September 18, 2018 - A massive study led Drs. Dean Fergusson, David Mazer and Richard Whitlock found that using lower hemoglobin thresholds to transfuse red blood cells during and after heart surgery is just as safe as using traditional thresholds. Hemoglobin is a protei
	High dose folic acid does not prevent preeclampsia in high-risk women September 12, 2018 - Taking high doses of folic acid throughout pregnancy does not prevent preeclampsia in high-risk women, according to a large international clinical trial published in The BMJ. This refutes the findings of previous observational studies and is expected
	Targeting cancer stem cells improves survival in certain kinds of colorectal cancer August 16, 2018 - An international clinical trial led by Dr. Derek Jonker found that a drug that targets cancer stem cells improved survival in patients with a specific form of colorectal cancer. Cancer stem cells make up a very small part of a some tumours. However,
	The cancer’s gone but the fear remains: psychology researchers tackle fear of cancer recurrence August 16, 2018 - A pilot study by Drs. Christina Tomei, Sophie Lebel, Christine Maheu, Monique Lefebvre, and Cheryl Harris suggests that specialized psychological services could help cancer survivors manage their fear of cancer returning. While this is a realistic fe
	People with rare blood cancer live longer, healthier lives with new targeted treatment regimen August 1, 2018 - A study published in the New England Journal of Medicine, co-authored by Dr. David MacDonald, is providing hope and changing lives for people with Waldenström's macroglobulinemia. This rare form of cancer occurs in white blood cells called B cells, w
	$1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss July 20, 2018 - Four research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $1.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). Their projects will advance sci
	Researchers push for better patient engagement June 27, 2018 - Research improves patient care, and a growing movement aims to engage and involve patients in the research process from start to finish. However, little is known about what meaningful patient engagement in research looks like. To find out, Dr. Dean F
	Dr. Dean Fergusson chosen as President-Elect of international clinical trial society June 20, 2018 - Dr. Dean Fergusson was elected President-Elect of the Society for Clinical Trials. This organization works internationally to advance human health by advocating for the use of clinical trials, leading the development and dissemination of optimal meth
	Economics professor cancer-free after immunotherapy trial for skin cancer May 3, 2018 - Economics professor Dr. David Gray took part in a clinical trial to see whether an immunotherapy drug could keep his high-risk skin cancer from coming back. Four years later, he’s still cancer-free.
	The Ottawa Hospital opens one-of-a-kind neuromuscular research centre May 1, 2018 - You can help!The Ottawa Hospital needs crucial equipment for neuromuscular research, including:An ultracentrifuge that separates cells into different components by spinning themat very high speed.This crucial piece of equipment can exert a force that
	Experimental stem cell therapy tested for rare lung disease April 30, 2018 - A Canadian-led research team has launched a clinical trial of an experimental stem cell therapy for pulmonary arterial hypertension. This rare and deadly disease occurs when the arteries that supply blood to the lungs become so damaged that blood can
	Aspirin as good as blood thinner for preventing blood clots after hip and knee replacement surgery April 6, 2018 - Drs. Paul Kim, Wade Gofton, Phil Wells, Marc Rodger, Marc Carrier and Doug Coyle co-authored a study in the New England Journal of Medicine that found aspirin to be just as good as the blood thinner rivaroxaban for preventing blood clots after a hip
	The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate January 30, 2018 - Sixteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $12.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a success r
	Electromagnetic field therapy improves survival in brain cancer patients January 19, 2018 - A JAMA study co-authored by Dr. Garth Nicholas shows that a wearable device that transmits low-intensity electrical fields into the brain can prolong survival in people with a highly aggressive form of brain cancer. The randomized trial included ne
	New treatment for our sickest patients comes closer to reality June 30, 2017 - The Ottawa Hospital was one of the top sites for enrolling patients in an international clinical trial of a promising new treatment for shock. The study, published in the New England Journal of Medicine, shows that a naturally-occurring protein calle
	New approach to clinical trials could revolutionize cancer care February 23, 2017 - Yasemin Heinbecker was a career diplomat used to working 10-hour days when she received a diagnosis last fall that stopped her busy life in its tracks. Like 25,000 other Canadian women every year, she was diagnosed with breast cancer and ended up “re
	Lung cancer breakthrough: 70% of patients with specific mutation respond to new therapy November 2, 2016 - A clinical trial led by Dr. Glen Goss has helped make a new kind of personalized therapy available for some patients with non-small cell lung cancer. Over the last 15 years, many of these patients have benefited greatly from drugs that target can
	Ottawa team pioneers new approach for cancer clinical trials September 28, 2016 - What is the most efficient way to answer the most important questions to improve care for cancer patients? Drs. John Hilton, Mark Clemons and Dean Fergusson got a group of Ottawa researchers together to answer this question and came up eight key
	MS breakthrough: Replacing diseased immune system halts progression and allows repair June 9, 2016 - Clinical trial suggests chemo and blood stem cell combination therapy should be considered for people with early, aggressive MS A clinical trial published in The Lancet, a top medical journal, shows that an intensive procedure that completely wipe
	Immunotherapy harnesses our own immune system to fight cancer May 18, 2016 - Ed Williams (left) didn’t expect to live more than six months after his skin cancer spread to his brain. But nearly three years later, he is alive and well thanks to immunotherapy. Michelle Renaud (right) is one of the registered nurses who admin

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Al Ghazawi, Feras MD, PhD, MSc, FRCPC, FAAD	Clinician Investigator (Clinical Epidemiology)	Cancer	Clinical research, Clinical trials, Drug development, Epidemiology, Immunotherapy, Translational research
Arnone, Danilo MD, PhD, FRCPsych	Clinician Investigator (Neuroscience)	Anxiety, Depression, Suicide	Biomarkers, Clinical trials, Cohort studies, Epidemiology, Neuro-stimulation, Psychology, Public health
Atkins, Harold MD, FRCPC	Senior Clinician Investigator (Cancer Therapeutics)	Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Cancer, Multiple sclerosis, Myasthenia gravis, Stiff person syndrome	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Immunotherapy, Oncolytic viruses, Regenerative medicine, Stem cells, Translational research, Transplantation, Viral therapy
Auer, Rebecca MD, MSc, FRCSC	Senior Scientist (Cancer Therapeutics)	Cancer, Colorectal cancer, Ovarian cancer, Pancreatic cancer	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical research, Clinical trials, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Peri-operative medicine, Quality Improvement, Surgery, Translational research, Viral therapy
Austin, Michael MD, FRCPC	Clinician Investigator (Clinical Epidemiology)	Asthma, Cardiac arrest, Chronic obstructive pulmonary disease, Diabetes, Pain, Population health, Stroke	Clinical decision rules, Clinical trials, Cluster randomized trials, Cohort studies, Critical care, Emergency medicine, Palliative care, Risk assessment
Black, Amanda MD, MPH, FRCSC	Associate Scientist (Clinical Epidemiology)	Pregnancy, Women's health	Clinical trials, Cohort studies, Health promotion, Surveys, Systematic reviews
Boet, Sylvain MD, PhD	Scientist (Clinical Epidemiology)	COVID-19	Anesthesiology, Behaviour, Clinical trials, Knowledge translation and implementation research, Patient engagement, Psychology, Qualitative methods, Quality Improvement, Surgery, Systematic reviews, Translational research
Bose, Gauruv MD, FRCPC	Associate Scientist (Neuroscience)	Autoimmune diseases of the nervous system, Multiple sclerosis	Artificial intelligence and data science, Biomarkers, Clinical decision rules, Clinical trials, Cohort studies, Health economics
Breau, Rodney MD	Scientist (Clinical Epidemiology)	Cancer, Kidney disease, Prostate cancer	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Imaging, Patient decision aids, Patient engagement, Quality Improvement, Surgery, Systematic reviews, Transfusions
Castellucci, Lana MD, FRCPC, MSc	Scientist (Clinical Epidemiology)	Thrombosis / thromboembolism	Clinical research, Clinical trials, Cohort studies, Critical care, Patient engagement, Systematic reviews, Transfusions
Clark, Edward MD MSc FRCPC	Associate Scientist (Clinical Epidemiology)	Kidney disease, Septic shock	Clinical research, Clinical trials, Epidemiology
Clemons, Mark MB BS, BMedSci, MSc, MD, FRCP, FRCPC	Scientist (Cancer Therapeutics)	Breast cancer, Cancer	Basic research, Clinical research, Clinical trials, Health research methods, Knowledge translation and implementation research
Dennis, Kristopher MD FRCPC PhD	Clinician Investigator (Cancer Therapeutics)	Cancer, Colorectal cancer, First Nations, Inuit and Métis Health, Gastric cancer, Liver cancer, Pain, Pancreatic cancer	Behaviour, Biomarkers, Clinical research, Clinical trials, Cohort studies, Health professional behaviour change, Health services research, Palliative care, Pragmatic trials, Qualitative methods, Quality Improvement, Systematic reviews
Dowlatshahi, Dariush MD PhD FRCP(C)	Senior Scientist (Neuroscience)	Subarachnoid hemorrhage, Stroke	Clinical trials, Digital and mobile health, Rehabilitation, Epidemiology
Duffett, Lisa MD	Associate Scientist (Clinical Epidemiology)	Thrombosis / thromboembolism	Clinical research, Clinical trials, Epidemiology
El-Chaar, Darine MD, FRCSC, Msc	Scientist (Clinical Epidemiology)	Autoimmune disease, COVID-19, Diabetes, Infectious disease, Inflammatory bowel syndrome, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
Fahed, Robert MD MSc	Associate Scientist (Neuroscience)	Stroke, Subarachnoid hemorrhage	Biostatistics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Imaging, Pragmatic trials, Quality Improvement, Shared decision making, Systematic reviews
Fergusson, Dean PhD, MHA, FCAHS	Program Director and Senior Scientist (Clinical Epidemiology)	Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease	Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Freedman, Mark HBSc, MSc, MD, CSPQ, FAAN, FRCPC	Senior Scientist (Neuroscience)	Multiple sclerosis	Cell therapy, Clinical research, Regenerative medicine, Clinical trials
Grimes, David MD, FRCPC	Associate Scientist (Neuroscience)	Huntington's, Parkinson's	Clinical research, Clinical trials, Patient decision aids
Harrison, Denise RN, PhD	Affiliate Investigator (Clinical Epidemiology)	Newborn and child health, Pain	Clinical trials, Cluster randomized trials, Knowledge translation and implementation research
Hatcher, Simon BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych	Scientist (Clinical Epidemiology)	Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide	Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Hiremath, Swapnil MD, MPH, FASN	Associate Scientist (Clinical Epidemiology)	Chronic disease, Diabetes, Health in older peoples, Heart disease, Hypertension, Kidney disease, Population health, Vascular, heart and metabolic disease	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health services research, Imaging, Pharmacology, Pragmatic trials, Public health, Quality Improvement, Systematic reviews
Hutton, Brian MSc, PhD	Senior Scientist (Clinical Epidemiology)	Addiction, Anxiety, Breast cancer, Depression, Health equity, Health in disadvantaged peoples, Maternal and fetal health, Mental health, Population health, Suicide, Cancer	Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Patient safety, Public health, Rapid reviews, Biostatistics, Clinical trials, Systematic reviews
Kekre, Natasha BSc, MD, MPH, FRCPC	Scientist (Clinical Epidemiology)	Blood cancer, Cancer	Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Epidemiology, Immunotherapy, Patient engagement, Stem cells, Translational research, Transplantation, Viral therapy
Lalu, Manoj MD, PhD, FRCPC	Scientist (Clinical Epidemiology)	Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease	Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Lavallee, Luke MDCM, MSc, FRCSC	Associate Scientist (Clinical Epidemiology)	Cancer, Kidney disease, Population health, Prostate cancer	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health professional behaviour change, Imaging, Knowledge translation and implementation research, Patient decision aids, Quality Improvement, Surgery, Systematic reviews
Le Gal, Gregoire MD, PhD	Senior Scientist (Clinical Epidemiology)	Thrombosis / thromboembolism	Clinical decision rules, Clinical research, Clinical trials, Epidemiology, Patient engagement, Peri-operative medicine
Lemaire, Edward PhD	Affiliate Investigator (Clinical Epidemiology)	Aging, Bone and joint degeneration, Bone and joint injuries, Concussion, Global health, Musculoskeletal conditions, Spinal cord injury, Traumatic brain injury, Traumatic injuries	3D printing, Big data, Clinical research, Clinical trials, Health research methods, Quality Improvement, Rehabilitation, Health technology
Liu, Johné PhD	Senior Scientist (Chronic Disease)	Aging, Cancer, Infertility, Maternal and fetal health, Pregnancy, Women's health	Basic research, Clinical research, Clinical trials, Disease models, Drug development, Translational research
Martel, Guillaume MD, MSc (Epi), FRCSC, FACS	Scientist (Clinical Epidemiology)	Anemia, Bleeding disorders, Colorectal cancer, Liver cancer, Liver disease, Pancreatic cancer	Anesthesiology, Clinical research, Clinical trials, Peri-operative medicine, Surgery, Systematic reviews, Transfusions
Matache, Bogdan MD	Clinician Investigator (Clinical Epidemiology)	Musculoskeletal conditions	Clinical trials, Surgery
McIntyre, Lauralyn MD, MHSc, FRCPC	Senior Scientist (Clinical Epidemiology)	Septic shock	Cell therapy, Clinical research, Clinical trials, Critical care, Patient engagement, Pragmatic trials, Stem cells, Transfusions, Translational research
McIsaac, Daniel MD, MPH, FRCPC	Scientist (Clinical Epidemiology)	Aging, Frailty, Health in older peoples, Pain, Population health	Anesthesiology, Artificial intelligence and data science, Big data, Biostatistics, Clinical research, Clinical trials, Cohort studies, Digital and mobile health, Epidemiology, Health services research, Patient engagement, Peri-operative medicine, Public health, Quality Improvement, Risk assessment, Surgery, Systematic reviews
Mestre, Tiago MSc MD	Scientist (Neuroscience)	Amyotrophic lateral sclerosis, Huntington's, Parkinson's	Clinical trials, Imaging
Morgan, Scott MD, MSc, FRCPC	Clinician Investigator (Cancer Therapeutics)	Bladder cancer, Breast cancer, Cancer, Prostate cancer	Biomarkers, Clinical research, Clinical trials, Cohort studies, Imaging, Systematic reviews
Nair, Vimoj MBBS MD MSc FRCPC	Clinician Investigator (Clinical Epidemiology)	Blood cancer, Brain cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pancreatic cancer	Cancer biotherapeutics, Clinical research, Clinical trials, Health technology, Imaging, Pragmatic trials, Quality Improvement, Translational research
Nessim, Carolyn MD, MSc, FRCSC, FACS	Clinician Investigator (Cancer Therapeutics)	Cancer, Colorectal cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Soft tissue sarcoma, Skin cancer	Biomarkers, Clinical trials, Gene expression, Immunotherapy, Surgery, Translational research, Viral therapy, Clinical research, Immunotherapy
Pakhale, Smita MD, FRCPC, MSc (Epi & Biostat)	Senior Scientist (Clinical Epidemiology)	COVID-19, First Nations, Inuit and Métis Health, Health equity, Health in disadvantaged peoples, Lung disease, Sickle cell anemia	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health services research, Patient engagement, Pragmatic trials, Public health, Quality Improvement
Poulin, Patricia C. Psych.	Associate Scientist (Clinical Epidemiology)	Addiction, Anxiety, Cancer, Chronic pain, Depression, Health equity, Musculoskeletal conditions, Pain	Anesthesiology, Behaviour, Biomarkers, Clinical research, Clinical trials, Emergency medicine, Epidemiology, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Palliative care, Patient decision aids, Patient safety, Peri-operative medicine, Pragmatic trials, Psychology, Qualitative methods, Quality Improvement, Systematic reviews
Ramsay, Timothy PhD	Senior Scientist (Clinical Epidemiology)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Rodger, Marc MD	Senior Scientist Affiliate (Clinical Epidemiology)	Pregnancy, Thrombosis / thromboembolism, Women's health	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Systematic reviews
Sabloff, Mitchell MSc, MDCM, FRCPC	Clinician Investigator (Clinical Epidemiology)	Blood cancer	Biomarkers, Clinical research, Clinical trials, Translational research
Sachs, Adam MD, MA, FRCSC	Associate Scientist (Neuroscience)	Amyotrophic lateral sclerosis, Spinal cord injury, Parkinson's	Artificial intelligence and data science, Clinical trials, Imaging, Neuro-stimulation, Surgery
Santos, Marlise MD (FRCPC), MSc, MPH	Clinician Investigator (Clinical Epidemiology)	Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Chronic disease, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Schramm, David MD SM FRCSC FACS	Associate Scientist (Clinical Epidemiology)	Cochlear implantation, Hearing loss	Biostatistics, Clinical research, Clinical trials, Epidemiology, Neuro-stimulation, Patient safety, Quality Improvement, Surgery, Systematic reviews
Seely, Jean MDCM, FRCPC	Clinician Investigator (Clinical Epidemiology)	Breast cancer, Cancer, Health equity, Population health, Women's health	Clinical trials, Cohort studies, Health technology, Imaging, Patient engagement, Public health, Quality Improvement, Surgery
Shamy, Michel MD MA FRCPC	Scientist (Neuroscience)	Stroke	Clinical trials, Imaging
Siegal, Deborah MD MSc FRCPC	Scientist (Clinical Epidemiology)		Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Systematic reviews
Singh, Sukhbir MD, FRCSC, FACOG	Associate Scientist (Clinical Epidemiology)	Chronic pain	Clinical trials, Health services research, Surgery, Surveys
Solmi, Marco MD, PhD, Psychiatrist	Clinician Investigator (Clinical Epidemiology)	Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews
Stacey, Dawn RN, PhD, CON(C)	Senior Scientist (Clinical Epidemiology)		Clinical research, Clinical trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient decision aids, Patient engagement, Qualitative methods, Quality Improvement, Shared decision making, Surveys, Systematic reviews
Stewart, Duncan MD, FRCPC	Senior Scientist (Regenerative Medicine)	COVID-19, Heart disease, Pulmonary hypertension, Septic shock, Vascular, heart and metabolic disease	Extracellular vesicles / exosomes, Stem cells, Cell therapy, Clinical trials, Molecular and cellular biology, Regenerative medicine, Translational research
Stiell, Ian MD, MSc, FRCPC	Senior Scientist (Clinical Epidemiology)	Chronic obstructive pulmonary disease, Heart disease	Clinical decision rules, Clinical trials, Emergency medicine
Taljaard, Monica PhD	Senior Scientist (Clinical Epidemiology)		Biostatistics, Clinical decision rules, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Quality Improvement
Tinmouth, Alan MD, FRCPC, MSc (Clin Epi)	Senior Scientist (Clinical Epidemiology)	COVID-19, Sickle cell anemia, Thalassemia	Clinical trials, Epidemiology, Transfusions
Tsai, Eve MD, PhD, FRCSC, CIP	Associate Scientist (Neuroscience)	Brain and neuromuscular disease, Cancer, Spinal cord injury	Biomaterials, Clinical research, Clinical trials, Imaging, Molecular and cellular biology, Regenerative medicine, Stem cells, Translational research
Vaillancourt, Christian MD, MSc, FRCPC, CSPQ	Senior Scientist (Clinical Epidemiology)	Cardiac arrest, Heart disease, Population health, Spinal cord injury, Traumatic brain injury, Traumatic injuries	Clinical decision rules, Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Critical care, Emergency medicine, Epidemiology, Health economics, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Public health, Quality Improvement, Surveys, Systematic reviews
Walker, Mark MD, FRCPC, MSc, MScHCM	Senior Scientist (Clinical Epidemiology)	Global health, Health equity, Infertility, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health research methods, Health services research, Knowledge translation and implementation research, Pragmatic trials, Prevention, Public health, Quality Improvement, Rapid reviews, Risk assessment, Surveys, Systematic reviews
Warman Chardon, Jodi MD, MSc, FRCPC (Neurology)	Associate Scientist (Neuroscience)	Amyotrophic lateral sclerosis, Genetic myopathy, Muscular dystrophy, Neuromuscular disease, Spinal muscular atrophy	Artificial intelligence and data science, Clinical research, Clinical trials, Exome sequencing analysis, Genetics, Imaging, MRI muscle imaging, Next generation sequencing, RNA sequencing, Genetics
Zimmerman, Deborah MD	Scientist (Clinical Epidemiology)	Frailty, Kidney disease	Clinical research, Clinical trials, Cohort studies, Epidemiology, Quality Improvement, Systematic reviews

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