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With autism, the brain adapts to blood vessel problems by changing how it uses energy
July 12, 2023
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Dr. Baptiste Lacoste wants to find out what’s going wrong with the blood vessels in the autistic brain.
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Prenatal exposure to low doses of methylmercury causes autism-like behaviors in mice
March 9, 2023
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A study co-led by Dr. Jing Wang and Dr. Laurie Chan is the first to show that exposing pregnant mice to low doses of methylmercury causes autism-like behaviors in their offspring.
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Researchers at The Ottawa Hospital awarded 19 CIHR grants worth more than $12 million
July 20, 2022
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These projects will advance science and improve health in areas such as cancer, neuroscience, regenerative medicine, autism, Kabuki Syndrome, kidney disease, patient engagement, blood transfusions, sepsis, surgery, anesthesia, plasma donation, muscle
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Do changes in brain metabolism play a role in autism? Prestigious grant to help researchers find out
June 7, 2022
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Dr. Baptiste Lacoste received a $550,000 grant from the U.S. Department of Defense Congressionally Directed Medical Research Programs to investigate whether brain metabolism could play a role in autism.
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Meet brain researcher Julie Ouellette
April 25, 2022
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“It’s so motivating working in the lab, because you’re seeing all this new information and you just want to get your message out into the world.”
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Beyond the brain: how autism impacts the body
April 30, 2021
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People with neurodevelopmental disorders like Down syndrome and autism spectrum disorders are at increased risk of conditions that affect the body’s metabolism including obesity, diabetes, and hypertension.
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Cannabis use in pregnancy linked to a greater risk of autism
August 10, 2020
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In the largest study of its kind, researchers from The Ottawa Hospital, BORN Ontario and the University of Ottawa found that children whose mothers reported using cannabis during pregnancy were at greater risk of autism.
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Vascular development may be at risk in autism
July 13, 2020
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A Canadian collaboration led by Dr. Baptiste Lacoste has undertaken the first ever in-depth study of vasculature in the autistic brain. The product of four years of work, a paper published today in Nature Neuroscience lays out several lines of novel
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New Frontiers in Research Fund supports trailblazing research on autism, Alzheimer’s, Parkinson’s
June 3, 2020
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Researchers from The Ottawa Hospital are involved in four new projects funded through the Exploration stream of Canada’s New Frontiers in Research Fund. The fund is designed to support high-risk, high-reward and interdisciplinary research.
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Study in mice reveals possible new target to treat autism
March 2, 2020
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The enzyme PTP1B may be a new target for treating autism spectrum disorder, according to a study published in Nature Communications.
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Scientist investigates how two gene mutations contribute to autism
April 24, 2019
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Dr. Pierre Mattar received $300,000 from the Simons Foundation to investigate how mutations of two genes contribute to autism.
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The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate
January 30, 2018
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Sixteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $12.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a success r
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Mice with big brains provide insight into brain regeneration and developmental disorders
May 15, 2012
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Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that mice that lack a gene called Snf2l have brains that are 35 per cent larger than normal. The research, led by Dr. David Picketts an
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