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Researchers at The Ottawa Hospital awarded three grants for high risk, high reward and interdisciplinary research
June 18, 2024
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The New Frontiers in Research Fund (NFRF) 2023 Exploration competition has awarded $33 million to support 133 research teams across Canada that bring diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
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Study could lead to new treatments for pulmonary hypertension and right heart failure
February 28, 2023
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The human heart has a remarkable ability to adapt and compensate in the face of injury and disease, but unfortunately this isn’t universal.
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Tiny particles hold promise for treating acute and chronic lung disease
February 17, 2022
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A meta-analysis of lab studies found that tiny particles called extracellular vesicles (EVs) released by mesenchymal stem/stromal cells (MSCs) have clear potential for treating acute lung injury,
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New research could explain why cells grow out of control in rare lung disease
May 9, 2018
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When cells grow out of control in the body, most people think of cancer, but this phenomenon also occurs in pulmonary arterial hypertension (PAH), a rare and deadly disease characterized by very high pressure in the arteries that supply blood to th
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Experimental stem cell therapy tested for rare lung disease
April 30, 2018
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A Canadian-led research team has launched a clinical trial of an experimental stem cell therapy for pulmonary arterial hypertension. This rare and deadly disease occurs when the arteries that supply blood to the lungs become so damaged that blood can
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How to trick your heart into thinking you exercise: cardiotrophin improves heart health and repairs damage in lab models
August 4, 2017
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Researchers have discovered that a protein called cardiotrophin 1 (CT1) can trick the heart into growing in a healthy way and pumping more blood, just as it does in response to exercise and pregnancy. They show that this good kind of heart growth i
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Researchers get $558K boost from Heart and Stroke Foundation
June 15, 2017
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Two scientists from The Ottawa Hospital and the University of Ottawa were successful in the Heart and Stroke Foundation’s recent grant-in-aid grant competition. Dr. Baptiste Lacoste was awarded $259,000* to test whether drugs that are already used
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Stem cell therapy shows promise in small clinical trial for rare lung disease
July 20, 2015
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Canadian researchers have published promising results of the first clinical trial in the world of a genetically-enhanced stem cell therapy for pulmonary arterial hypertension (PAH).
This rare and deadly disease mainly affects young women, and i
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