Ottawa Hospital Research Institute

Research News

	Reinvigorating immunotherapy: clinical trial provides new hope for lung cancer patients February 23, 2024 - The Ottawa Hospital played a key role in an international clinical trial that is providing new hope for people with advanced non-small cell lung cancer (NSCLC).
	Immunotherapy improves survival with mesothelioma lung cancer January 4, 2024 - An international clinical trial published in The Lancet shows that immunotherapy improves survival in people with an aggressive type of lung cancer called pleural mesothelioma.
	Capturing immunotherapy response in a blood drop October 26, 2023 - A clinical trial published in Nature Medicine suggests that using a “liquid biopsy” to measure tiny bits of tumour DNA in blood could determine if immunotherapy drugs are working in patients with advanced non-small cell lung cancer.
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	How a lung cancer survivor advocate is helping advance research that will lead to early detection February 7, 2020 - In September of 2013, Jill Hamer-Wilson caught something many of us tend to catch this time of year – a cold. While the cold eventually went away, a cough remained, and lingered for quite some time. Little did Jill know that this was an early sign of
	3D gel helps researchers find potential drugs for lung cancer, other diseases March 15, 2019 - Researchers in Ottawa and Toronto have created a spongy 3D gel that mimics lung tissue, allowing them to quickly screen hundreds of potential drugs for lung cancer and other diseases.
	Report suggests tobacco smoking rates will drop to below 10% in about 20 years July 17, 2018 - Ontario will achieve "single digit" tobacco smoking rates (under 10 per cent) by 2023 for women, and 2040 for men, according to a new big data report conducted jointly by the Institute for Clinical Evaluative Sciences (ICES) and The Ottawa
	Dr. Glen Goss recognized for lifetime achievement in lung cancer March 29, 2018 - Dr. Glen Goss recently received the Lifetime Achievement Award at the Canadian Lung Cancer Conference in Vancouver. This award recognizes his leadership in improving care for people with lung cancer, both as an oncologist and as a researcher. Dr. G
	Could old drugs target lung cancer in a new way? February 23, 2017 - Dr. Doug Gray received a $196,000 grant from a partnership of the Canadian Cancer Society Research Institute and Canadian Institutes of Health Research to investigate new ways to prevent lung cancer from spreading. By the time most patients with lu
	Lung cancer breakthrough: 70% of patients with specific mutation respond to new therapy November 2, 2016 - A clinical trial led by Dr. Glen Goss has helped make a new kind of personalized therapy available for some patients with non-small cell lung cancer. Over the last 15 years, many of these patients have benefited greatly from drugs that target can
	$2-million project aims to bring personalized medicine to lung cancer care October 11, 2016 - A team led by Dr. David Stewart, Dr. Bryan Lo, Dr. Pearl Campbell and Craig Ivany has received $2 million from Genome Canada and partners to develop a test that can better deliver personalized care for patients with non-small cell lung cancer. So

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Addison, Christina PhD	Senior Scientist (CR)	Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer	Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele PhD	Senior Scientist (CR)	Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma	Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Gilbert, Sebastien MD FRCSC	Clinician Investigator (ACR)	Cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Lung cancer, Lung disease	Artificial intelligence and data science, Clinical research, Epidemiology, Health technology, Quality Improvement
Gray, Douglas PhD	Senior Scientist Emeritus (CR)	Aging, Cancer, Lung cancer, Parkinson's	Basic research, Disease models, Genomics, Imaging, Transgenic/knockout models, Genetics, Model organisms, Molecular and cellular biology
Islam, Shahidul MD, PhD, FRCPC, FCAP	Clinician Investigator (CR)	Cancer, Endometrial cancer, Lung cancer, Ovarian cancer, Thyroid cancer
Patino, Paula MD	Clinician Investigator (ICD)	Lung cancer
Ramsay, Timothy PhD	Senior Scientist (MIR)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Stanford, William PhD	Senior Scientist (RM)	Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease	Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology

Related Resources

Ottawa Hospital Research Institute Cancer Therapeutics Program

The Ottawa Hospital Cancer Program

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Lung cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "Lung cancer" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Implementation of Liquid Biopsy in Non-Small-Cell Lung Cancer: An Ontario Perspective.
2024-10-25

Pulmonary Nocardiosis in a Non-Small Cell Lung Cancer Patient Being Treated for Pembrolizumab-Associated Pneumonitis.
2024-10-25

A Phase II Study of Neoadjuvant Opnurasib KRAS G12C Inhibitor in Patients With Surgically Resectable Non-Small Cell Lung Cancer (CCTG IND.242A): A Substudy of the IND.242 Platform Master Protocol.
2024-10-12

Appendicitis while on alectinib for non-small cell lung cancer: a tale of two case reports.
2024-10-11

Pathways to cancer care after a suspected cancer diagnosis in the emergency department: a survey of emergency physicians across Ontario.
2024-10-07

Ponsegromab for the Treatment of Cancer Cachexia.
2024-09-17

Treatment patterns and outcomes in KRAS(G12C)-positive advanced NSCLC patients previously treated with immune checkpoint inhibitors: A Canada-wide real-world, multi-center, retrospective cohort study.
2024-07-30

Long-Term Prospective Outcomes of Intensity Modulated Radiotherapy for Locally Advanced Lung Cancer: A Secondary Analysis of a Randomized Clinical Trial.
2024-06-27

Recommendations to Improve Management of Incidental Pulmonary Nodules in Canada: Expert Panel Consensus.
2024-06-13

Determining optimal air leak resolution criteria when using digital pleural drainage device after lung resection.
2024-05-01

View more on PubMed