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Lung cancer

Researchers at The Ottawa Hospital are investigating promising new approaches to prevent, diagnose and treat lung cancer. This page includes selected news stories about our lung cancer research, links to researchers working in this area and related resources.

Research News

Reinvigorating immunotherapy: clinical trial provides new hope for lung cancer patients
February 23, 2024 - The Ottawa Hospital played a key role in an international clinical trial that is providing new hope for people with advanced non-small cell lung cancer (NSCLC).
Immunotherapy improves survival with mesothelioma lung cancer
January 4, 2024 - An international clinical trial published in The Lancet shows that immunotherapy improves survival in people with an aggressive type of lung cancer called pleural mesothelioma.
Capturing immunotherapy response in a blood drop
October 26, 2023 - A clinical trial published in Nature Medicine suggests that using a “liquid biopsy” to measure tiny bits of tumour DNA in blood could determine if immunotherapy drugs are working in patients with advanced non-small cell lung cancer.
Show more news stories


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Addison, Christina
Senior Scientist
Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele
Senior Scientist
Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Gilbert, Sebastien
Clinician Investigator
Cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Lung cancer, Lung disease Artificial intelligence and data science, Clinical research, Epidemiology, Health technology, Quality Improvement
Gray, Douglas
Senior Scientist Emeritus
Aging, Cancer, Lung cancer, Parkinson's Basic research, Disease models, Genomics, Imaging, Transgenic/knockout models, Genetics, Model organisms, Molecular and cellular biology
Islam, Shahidul
Clinician Investigator
Cancer, Endometrial cancer, Lung cancer, Ovarian cancer, Thyroid cancer
Patino, Paula
Clinician Investigator
Lung cancer
Ramsay, Timothy
Senior Scientist
Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Stanford, William
Senior Scientist
Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology

Clinical Trials

The following list of clinical trials is pulled from using the search terms "Lung cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit to learn more about participating in research and clinical trials.

Note that is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCT05488314A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer (NCT05488314)Carcinoma, Non-Small-Cell LungRECRUITING 
NCT04895709A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors (NCT04895709)Cervical Cancer, Gastric/Gastroesophageal Junction Adenocarcinoma, Microsatellite Stable Colorectal Cancer, Non-Small-Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Urothelial Carcinoma, Pancreatic Adenocarcinoma, Melanoma, Ovarian Neoplasms, Triple Negative Breast NeoplasmsRECRUITING 
NCT05571839A Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors (NCT05571839)Cutaneous Melanoma, Non-small Cell Lung Cancer, Colorectal Neoplasms, Pancreatic Neoplasms, MesotheliomaRECRUITING 
NCT04260802A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers (NCT04260802)Cancer, Neoplasms, Metastatic Cancer, Triple Negative Breast Cancer, Gastric Cancer, Cervical Cancer, Ovarian Cancer, Hepatocellular Carcinoma, Squamous Cell Carcinoma of Head and Neck, Urothelial Carcinoma, Urothelial Neoplasm, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Locally Advanced Solid Tumor, Locally Advanced Malignant Neoplasm, Squamous Cell Carcinoma, Sarcoma, Merkel Cell Carcinoma, Bladder CancerRECRUITING 
NCT04449874A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation (NCT04449874)Non-Small Cell Lung Cancer, Colorectal Cancer, Advanced Solid TumorsRECRUITING 
NCT05538130A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors (NCT05538130)Melanoma, Glioma, Thyroid Cancer, Non-Small Cell Lung Cancer, Malignant Neoplasms, Brain Neoplasms, Colorectal CancerRECRUITING 
NCT05355701A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. (NCT05355701)Melanoma, Non-Small-Cell Lung Cancer, Thyroid Cancer, GliomaRECRUITING 
NCT04609566Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors (NCT04609566)Melanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and NeckRECRUITING 
NCT02468024JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer (NCT02468024)Non-Small Cell Lung;
NCT05714891Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer (NCT05714891)NSCLCRECRUITING 
NCT02906943Ontario-wide Cancer TArgeted Nucleic Acid Evaluation (NCT02906943)Breast Cancer, Lung Cancer, Colorectal Cancer, Melanoma, Gynecological Cancer, Genitourinary Cancer, Pancreatobiliary Cancer, Gastrointestinal Cancer, Head and Neck Cancer, Rare Cancer, Unknown Primary CancerRECRUITING 
NCT04335292Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer With Osimertinib Third-line Rechallenge (NCT04335292)Non-Small Cell Lung CancerRECRUITING 
NCT05184712Phase 3 Clinical Study of AK112 for NSCLC Patients (NCT05184712)Non-Squamous Non-small Cell Lung CancerRECRUITING 
NCT04093167Study of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC (NCT04093167)Non-Small Cell Lung CancerRECRUITING 
NCT05954871Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer (NCT05954871)Colorectal Cancer, Non-Small Cell Lung CancerRECRUITING 
NCT04871412The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage II (NCT04871412)Lung Cancer, Gastric Cancer, Esophageal CancerRECRUITING 
NCT04894591To Assess the Effectiveness and Safety of Zepzelca in Adult Patients With Extensive Stage Small Cell Lung Cancer (SCLC) (NCT04894591)Extensive-stage Small-cell Lung CancerRECRUITING