Research News

	Capturing immunotherapy response in a blood drop October 26, 2023 - A clinical trial published in Nature Medicine suggests that using a “liquid biopsy” to measure tiny bits of tumour DNA in blood could determine if immunotherapy drugs are working in patients with advanced non-small cell lung cancer.
	How a lung cancer survivor advocate is helping advance research that will lead to early detection February 7, 2020 - In September of 2013, Jill Hamer-Wilson caught something many of us tend to catch this time of year – a cold. While the cold eventually went away, a cough remained, and lingered for quite some time. Little did Jill know that this was an early sign of
	3D gel helps researchers find potential drugs for lung cancer, other diseases March 15, 2019 - Researchers in Ottawa and Toronto have created a spongy 3D gel that mimics lung tissue, allowing them to quickly screen hundreds of potential drugs for lung cancer and other diseases.
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	Report suggests tobacco smoking rates will drop to below 10% in about 20 years July 17, 2018 - Ontario will achieve "single digit" tobacco smoking rates (under 10 per cent) by 2023 for women, and 2040 for men, according to a new big data report conducted jointly by the Institute for Clinical Evaluative Sciences (ICES) and The Ottawa
	Dr. Glen Goss recognized for lifetime achievement in lung cancer March 29, 2018 - Dr. Glen Goss recently received the Lifetime Achievement Award at the Canadian Lung Cancer Conference in Vancouver. This award recognizes his leadership in improving care for people with lung cancer, both as an oncologist and as a researcher. Dr. G
	Could old drugs target lung cancer in a new way? February 23, 2017 - Dr. Doug Gray received a $196,000 grant from a partnership of the Canadian Cancer Society Research Institute and Canadian Institutes of Health Research to investigate new ways to prevent lung cancer from spreading. By the time most patients with lu
	Lung cancer breakthrough: 70% of patients with specific mutation respond to new therapy November 2, 2016 - A clinical trial led by Dr. Glen Goss has helped make a new kind of personalized therapy available for some patients with non-small cell lung cancer. Over the last 15 years, many of these patients have benefited greatly from drugs that target can
	$2-million project aims to bring personalized medicine to lung cancer care October 11, 2016 - A team led by Dr. David Stewart, Dr. Bryan Lo, Dr. Pearl Campbell and Craig Ivany has received $2 million from Genome Canada and partners to develop a test that can better deliver personalized care for patients with non-small cell lung cancer. So

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Addison, Christina PhD	Senior Scientist (Cancer Therapeutics)	Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer	Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele PhD	Senior Scientist (Cancer Therapeutics)	Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma	Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Gilbert, Sebastien MD FRCSC	Clinician Investigator (Clinical Epidemiology)	Cancer, Gastric cancer, Gastrointestinal disease, Gastrointestinal stromal tumours (GIST), Lung cancer, Lung disease	Artificial intelligence and data science, Clinical research, Epidemiology, Health technology, Quality Improvement
Gray, Douglas PhD	Senior Scientist Emeritus (Cancer Therapeutics)	Aging, Cancer, Lung cancer, Parkinson's	Basic research, Disease models, Genomics, Imaging, Transgenic/knockout models, Genetics, Model organisms, Molecular and cellular biology
Islam, Shahidul MD, PhD, FRCPC, FCAP	Clinician Investigator (Cancer Therapeutics)	Cancer, Endometrial cancer, Lung cancer, Ovarian cancer, Thyroid cancer
Ramsay, Timothy PhD	Senior Scientist (Clinical Epidemiology)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Stanford, William PhD	Senior Scientist (Regenerative Medicine)	Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease	Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology

Related Resources

Ottawa Hospital Research Institute Cancer Therapeutics Program

The Ottawa Hospital Cancer Program

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Lung cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "Lung cancer" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Unveiling the anticancer mechanism of 1,2,3-triazole-incorporated thiazole-pyrimidine-isoxazoles: insights from docking and molecular dynamics simulations.
2023-12-01

Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label, randomised controlled trial.
2023-11-07

Profound DNA methylomic differences between single- and multi-fraction alpha irradiations of lung fibroblasts.
2023-10-28

Prediction of Acute Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy Using Dose-Volume Parameters From Functional Mapping on Gallium 68 Perfusion Positron Emission Tomography/Computed Tomography.
2023-10-25

Previous Ischemic Stroke Significantly Alters Stroke Risk in Newly Diagnosed Cancer Patients.
2023-10-18

A 20-Year Update on the Practice of Thoracic Surgery in Canada: A Survey of the Canadian Association of Thoracic Surgeons.
2023-10-11

ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results.
2023-10-10

Appraising publicly available online resources to support patients considering decisions about medical assistance in dying in Canada: an environmental scan.
2023-10-04

4D Monte Carlo dose reconstructions using surface motion measurements.
2023-09-23

The Inherited KRAS-variant as a Biomarker of Cetuximab Response in NSCLC.
2023-09-20

View more on PubMed