Ottawa Hospital Research Institute

Research News

	Cancer-fighting viruses soften up their victims before attacking April 7, 2022 - A research team based at The Ottawa Hospital and the University of Ottawa has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attac
	BRCA mutated pancreatic cancer: A change is coming June 1, 2021 - Pancreatic cancer remains a leading cause of cancer-related death with few available therapies for advanced disease. Recently, patients with germline BRCA mutations have received increased attention due to advances in the management of BRCA mutated o
	New research chair to lead cutting-edge work in liver and pancreatic cancer September 10, 2019 - The Ottawa Hospital and the University of Ottawa are pleased to announce the appointment of Dr. Guillaume Martel as the first Arnie Vered Family Chair in Hepato-Pancreato-Biliary Research.
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	The Ottawa Hospital awarded 18 research grants from the Canadian Institutes of Health Research, worth $10.7 million May 19, 2017 - Eighteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded nearly $11 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a suc
	Pancreatic cancer loses viral defences when talking with supporting cells April 20, 2015 - Ottawa researchers have unlocked a way to make pancreatic cancer cells more vulnerable to cancer-killing viruses, known as oncolytic viruses. Outlined in a paper published today by Nature Medicine, the scientists have discovered how they can exploit
	Dr. Rebecca Auer awarded $450,000 to develop novel immunotherapy for pancreatic cancer April 15, 2015 - Pancreatic cancer is one of the most deadly cancers. Surgery provides the best chance of a cure, but even then, more than 80% of patients will die of their disease. However, immunotherapies, which harness the body’s own immune system to attack cancer
	$1.2M to advance the treatment of pancreatic cancer April 2, 2014 - The Canadian Cancer Society has awarded Dr. John Bell an Impact Grant totalling $1.2 million over the next five years to further his research into the use of viruses to fight pancreatic cancer, one of the deadliest forms of cancer. According to the

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Addison, Christina PhD	Senior Scientist (CR)	Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer	Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele PhD	Senior Scientist (CR)	Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma	Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Auer, Rebecca MD, MSc, FRCSC	Senior Scientist (CR)	Cancer, Colorectal cancer, Ovarian cancer, Pancreatic cancer	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical research, Clinical trials, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Peri-operative medicine, Quality Improvement, Surgery, Translational research, Viral therapy
Dennis, Kristopher MD FRCPC PhD	Clinician Investigator (CR)	Cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pain, Pancreatic cancer	Behaviour, Biomarkers, Clinical research, Clinical trials, Cohort studies, Health professional behaviour change, Health services research, Palliative care, Pragmatic trials, Qualitative methods, Quality Improvement, Systematic reviews
Ilkow, Carolina PhD	Senior Scientist (CR)	Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer	Basic research, Cancer biotherapeutics, Cancer immunotherapy, Extracellular vesicles / exosomes, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Martel, Guillaume MD, MSc (Epi), FRCSC, FACS	Senior Scientist (ACR)	Anemia, Bleeding disorders, Colorectal cancer, Liver cancer, Liver disease, Pancreatic cancer	Anesthesiology, Clinical research, Clinical trials, Peri-operative medicine, Surgery, Systematic reviews, Transfusions
Nair, Vimoj MBBS MD MSc FRCPC	Clinician Investigator (CR)	Blood cancer, Brain cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pancreatic cancer	Artificial intelligence and data science, Biostatistics, Cancer biotherapeutics, Clinical research, Clinical trials, Health technology, Imaging, Pragmatic trials, Quality Improvement, Translational research
Zayed, Sondos MD CM, FRCPC, MPH	Clinician Investigator (CR)	Brain cancer, Cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pancreatic cancer	Clinical research, Clinical trials, Epidemiology, Pragmatic trials, Systematic reviews

Related Resources

Ottawa Hospital Research Institute Cancer Research Program

The Ottawa Hospital Cancer Program

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Pancreatic cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "Pancreatic cancer" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

The tandem duplicator phenotype may be a novel targetable subgroup in pancreatic cancer.
2025-04-04

Administration of FOLFIRINOX for Advanced Pancreatic Cancer: Physician Practice Patterns During Early Use.
2025-02-25

Canadian Association of Radiologists Cancer Diagnostic Imaging Referral Guideline.
2025-01-22

Anticoagulation for the prevention of arterial thromboembolism in cancer patients by primary tumour site: a systematic review and meta-analysis of randomized trials.
2025-01-11

Development and Validation of a Survival Prediction Model for Patients With Pancreatic Cancer.
2025-01-01

Ponsegromab for the Treatment of Cancer Cachexia.
2024-12-19

Percentage of Pancreatic Cysts on MRI With a Pancreatic Carcinoma: Systematic Review and Meta-Analysis.
2024-09-01

Molecular Characterization and Xenotransplantation of Pancreatic Cancer Using Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA).
2024-07-31

Aspirin exposure and its association with metal stent patency in malignant distal biliary obstruction: a large international multicenter propensity score-matched study.
2024-04-01

A 15-Year Single-Institution Retrospective Study of Primary Pancreatic Cancer Treated with Non-Ablative Palliative Radiotherapy.
2024-02-22

View more on PubMed