|
Tumour engineering could provide a powerful new approach to make more cancer patients eligible for targeted immunotherapies
September 26, 2024
-
There are many highly-effective immunotherapies available in the clinic, but few cancer patients are eligible for these treatments because their tumours must have specific targetable proteins. A new tumour engineering approach could help.
|
|
Immunotherapy improves survival with mesothelioma lung cancer
January 4, 2024
-
An international clinical trial published in The Lancet shows that immunotherapy improves survival in people with an aggressive type of lung cancer called pleural mesothelioma.
|
|
The Ottawa Hospital, the University of Ottawa, and McMaster University join forces to prepare Canada for future pandemics
March 2, 2023
-
Building on the knowledge gained over nearly three years of the COVID-19 pandemic, The Ottawa Hospital (TOH), the University of Ottawa and McMaster University are joining forces with partners to create the Canadian Pandemic Preparedness Hub (CP2H).
|
|
Show more news stories
|
|
Canadian-Led Immunotherapies in Cancer (CLIC) program inspires innovative CAR-T trial in Denmark
December 8, 2022
-
CAR-T therapy is a groundbreaking cancer treatment that involves genetically engineering a patient’s own immune cells to attack their cancer. While this therapy is commercially available in many countries, cancer researchers are also developing their
|
|
Drilling down to improve CAR T therapy
May 4, 2022
-
Dr. Dean Fergusson and his team are drilling down into clinical trial data, which is normally reported at an aggregate level, at the individual patient level to get more information about who benefits most from CAR T therapy and under what conditions
|
|
Kiss of sleep: how blood cancer cells put the immune system’s Natural Killer cells to sleep
April 13, 2022
-
Researchers at The Ottawa Hospital and the University of Ottawa have discovered that a kind of kiss between cells, called trogocytosis, plays a key role in the battle between the immune system and blood cancer cells.
|
|
Personalized anti-cancer vaccine shows promise in mice
January 28, 2022
-
Treatments for cancer are becoming increasingly personalized, not just to a type of cancer, but even to an individual patient. A new study successfully applies this strategy in a new way in mouse models.
|
|
Translational research grant could help to develop new immunotherapies for leukemia
April 5, 2021
-
While CAR-T and other forms of immunotherapy are providing new hope for people with acute B-cell leukemia (B-ALL), much less progress has been made in treating acute T-cell leukemia (T-ALL).
|
|
Cancer team awarded $5M for cell-based immunotherapy research
March 3, 2021
-
Researchers at The Ottawa Hospital and the University of Ottawa are partnering with colleagues across the country to expand Canada’s capacity to develop new cell-based immunotherapies for cancer with a $5.2 million grant from the Canada Foundation fo
|
|
Protecting cancer patients from COVID-19
July 8, 2020
-
In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations – cancer patients.
|
|
Often-overlooked Natural Killer cells may be key to cancer immunotherapy
September 10, 2018
-
Immune checkpoint inhibitors are revolutionizing the treatment of cancer, but new research challenges the central dogma of how these drugs work. This research, published in the prestigious Journal of Clinical Investigation, shows for the first time t
|
|
Researchers uncover possible new mechanism to enhance cancer-killing viruses
July 11, 2018
-
Cancer-killing (oncolytic) viruses have shown promise in the lab and the clinic, but they don’t always work. New research led by Dr. Carolina Ilkow could help change this. While normal cells often lose their first line of antiviral defenses when they
|
.jpg)
|
Sex, viruses and cancer: Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery
May 17, 2018
-
A new study suggests that a common treatment for erectile dysfunction combined with the flu vaccine may be able to help the immune system mop up cancer cells left behind after surgery. The study, published in OncoImmunology, shows that this unconvent
|
|
Could viruses take cancer immunotherapy to the next level? Study shows viruses and checkpoint inhibitors work together to cure resistant breast cancer in mice
January 3, 2018
-
Immunotherapy, which helps the body’s immune system attack cancer, has revolutionized treatment for cancers such as melanoma and leukemia. However, many other kinds of cancer remain resistant. A new study led by researchers at The Ottawa Hospital and
|
|
Ottawa researchers to play lead role in new cancer immunotherapy studies
February 15, 2017
-
BioCanRx funds research into CAR-T and virus-infected cell therapy
Researchers from The Ottawa Hospital and the University of Ottawa will play a lead role in cutting-edge research on cancer immunotherapy, thanks to five new peer-reviewed researc
|
.jpg)
|
Virus vs. Prostate Cancer: Canadian Researchers Pioneer Next-generation Therapy
-- Prostate Cancer Canada and the Movember Foundation partner to make innovative work possible
September 30, 2015
-
A multi-disciplinary team of scientists and clinicians led by Dr. John Bell of The Ottawa Hospital is developing a treatment for prostate cancer using viruses that destroy cancer cells and boost the anti-cancer immune response, all the while leaving
|
