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Brain cancer

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of brain cancer and develop better treatments. This page includes selected news stories about our brain cancer research, links to researchers working in this area and related resources. Learn more below.

Research News


Researchers at The Ottawa Hospital awarded 18 CIHR grants worth more than $11 million Researchers at The Ottawa Hospital awarded 18 CIHR grants worth more than $11 million
February 5, 2022 - These projects will advance science and improve health in areas such as tuberculosis, blood disease, prostate cancer, heart disease, muscle repair, sleep apnea, brain cancer, medical imaging, virtual care, prehab, intellectual disability, sarcoma, CA
A glimpse inside the mind of neurosurgery expert, Dr. Fahad Alkherayf A glimpse inside the mind of neurosurgery expert, Dr. Fahad Alkherayf
August 18, 2021 - Dr. Fahad Alkherayf is the Director of the Clinical Research Program in the Neurosurgery Division of The Ottawa Hospital. As a neurosurgeon, he specializes in minimally invasive surgeries, which use much smaller incisions than traditional surgeries
Researchers discover new kind of brain tumour Researchers discover new kind of brain tumour
July 8, 2019 - Dr. John Woulfe and his colleagues have identified a new kind of brain tumour. It was removed during a young woman’s treatment, and did not match any existing tumour classifications.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Ardolino, Michele
PhD
Senior Scientist
(CR)
Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Aviv, Richard
MBChB, FRCR (UK), FRCPC, dABR
Clinician Investigator
(NS)
Brain and neuromuscular disease, Brain cancer, Head and neck cancer, Multiple sclerosis, Stroke, Subarachnoid hemorrhage, Traumatic brain injury, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Clinical research, Cluster randomized trials, Disease models, Health economics, Health technology, Imaging, Patient safety, Quality Improvement, Translational research
Chakraborty, Santanu
MBBS, MRCP, DMRD, FRCR, FRCP(C)
Senior Clinician Investigator
(NS)
Amyotrophic lateral sclerosis, Brain cancer, Concussion, Dementia, Head and neck cancer, Multiple sclerosis, Parkinson's, Spinal cord injury, Stroke, Traumatic brain injury Bioinformatics, Clinical research, Health economics, Health professional behaviour change, Imaging, Immunization, Patient safety, Quality Improvement, Risk assessment
Lorimer, Ian
PhD
Senior Scientist
(CR)
Brain and neuromuscular disease, Brain cancer, Cancer Basic research, Cancer biotherapeutics, Cell therapy, Disease models, Molecular and cellular biology, Translational research
Nair, Vimoj
MBBS MD MSc FRCPC
Clinician Investigator
(CR)
Blood cancer, Brain cancer, Colorectal cancer, Gastric cancer, Liver cancer, Pancreatic cancer Artificial intelligence and data science, Biostatistics, Cancer biotherapeutics, Clinical research, Clinical trials, Health technology, Imaging, Pragmatic trials, Quality Improvement, Translational research
Puac Polanco, Paulo
MD
Clinician Investigator
(NS)
Brain cancer, Head and neck cancer, Stroke Imaging
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(NS)
Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Woulfe, John
PhD, MD
Associate Scientist
(NS)
Brain and neuromuscular disease, Brain cancer, Cancer, Parkinson's Basic research, Clinical research, Translational research




Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "(brain cancer OR glioblastoma OR glioma OR medulloblastoma)” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCTTitleConditionStatusContact
NCT05538130A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors (NCT05538130)Melanoma, Glioma, Thyroid Cancer, Non-Small Cell Lung Cancer, Malignant Neoplasms, Brain Neoplasms, Colorectal CancerRECRUITING 
NCT05355701A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. (NCT05355701)Melanoma, Non-Small-Cell Lung Cancer, Thyroid Cancer, GliomaRECRUITING 
NCT05326334THERApeutic Outcomes Related to Gut microBIOME in Glioblastoma (GBM) Patients Receiving Chemo-radiation (THERABIOME-GBM) (NCT05326334)Glioblastoma, IDH-wildtypeRECRUITING 


Publications

The following research publications are pulled from PubMed using the search terms "brain cancer OR glioblastoma OR glioma OR medulloblastoma" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Guidance for Canadian Breast Cancer Practice: National Consensus Recommendations for the Systemic Treatment of Patients with HER2+ Breast Cancer in Both the Early and Metastatic Setting.
2024-11-26

Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada.
2024-11-14

Master regulators of neurogenesis: the dynamic roles of Ephrin receptors across diverse cellular niches.
2024-11-07

Atlas of gray matter volume differences across psychiatric conditions: A systematic review with a novel meta-analysis that considers co-occurring disorders.
2024-11-04

Brain malformations and seizures by impaired chaperonin function of TRiC.
2024-11-03

Targeting glioblastoma with a brain-penetrant drug that impairs brain tumor stem cells via NLE1-Notch1 complex.
2024-10-19

Collaborative outcomes study on health and functioning during infection times (COH-FIT): Insights on modifiable and non-modifiable risk and protective factors for wellbeing and mental health during the COVID-19 pandemic from multivariable and network analyses.
2024-09-29

Combination treatment with histone deacetylase and carbonic anhydrase 9 inhibitors shows therapeutic potential in experimental diffuse intrinsic pontine glioma.
2024-09-24

Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study.
2024-09-22

Gadolinium Reduction in Brain Tumor Imaging: A Paradigm Shift in Diagnostic Strategies.
2024-08-27

View more on PubMed