Ottawa Hospital Research Institute

Research News

	Meet HIV researcher Megan Magro April 25, 2022 - When she’s not doing artistic swimming, Megan Magro is in the lab working towards a cure for HIV.
	Virus versus virus: novel approach shows promise against HIV in lab study July 12, 2021 - Thanks to the development of effective drugs, HIV has become a chronic, treatable condition for most people. But it still isn’t curable, and that isn’t good enough for Dr. Jonathan Angel and his colleagues.
	The Ottawa Hospital contributes to ‘a beautiful evolution’ in HIV research and care December 4, 2020 - In honour of World AIDS day, we take a look back at how The Ottawa Hospital played a major role in caring for patients with HIV, how it continues to lead life-saving research, and how it is transforming how HIV is managed today.
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	The next frontier in HIV research: Ottawa scientists to play key role in new $17M prevention and cure studies August 14, 2019 - Despite great strides in HIV research, over 75,000 Canadians are living with HIV and approximately seven more contract it every day. And this incurable virus continues to take a huge toll around the world. The Government of Canada recently announced
	Experimental contraceptive could give women the power to prevent pregnancy and STIs November 30, 2018 - While condoms are the gold standard for preventing pregnancy and Sexually Transmitted Infections (STIs), there is a need around the world for solutions that can be used independently by women. New research led by Dr. Nongnuj Tanphaichitr brings a pot
	Using viruses to fight viruses: new approach eliminates “dormant” HIV-infected cells December 18, 2017 - While Ottawa researchers are known for their work on cancer-fighting viruses, one team is applying these viruses to a new target: HIV. Researchers at The Ottawa Hospital and the University of Ottawa have discovered that the Maraba virus, or MG1, c
	HIV kept at bay with single injection every 8 weeks August 17, 2017 - Over the last two decades, HIV has been transformed from a death sentence into a chronic, treatable disease, requiring just a single pill a day to keep the virus at bay for most people. A study co-authored by Dr. Jonathan Angel has now paved the wa
	Dr. Paul MacPherson awarded Research Chair in Gay Men’s Health from Ontario HIV Treatment Network September 7, 2016 - Gay men make up 58 percent of the people living with HIV in Ontario. Although overall rates of new HIV infections are declining, gay men accounted for 60 percent of new diagnoses in 2015, highlighting the continuing risk of infection within this co
	Two lives forever changed by 30 years of HIV drug research April 22, 2016 - Yves Brunet has taken part in 15 HIV drug trials at The Ottawa Hospital since the 1980s. Thanks to research, daily treatments have commuted a sentence of certain death from AIDS into a manageable condition. Yves Brunet and Andy Collins were di
	New treatments cure hepatitis C in patients co-infected with HIV July 29, 2015 - Around the world, between 4 and 5 million people are infected with both HIV and the hepatitis C virus. These patients have high rates of liver disease. Until now, effective treatment for co-infected patients has been difficult since the interferon-
	How does the liver affect the immune system? $175,000 grant to help find answers June 10, 2015 - Dr. Angela Crawley has been awarded a $175,000 grant from the Natural Sciences and Engineering Research Council of Canada to study how cells in the liver can influence the immune response. This project focuses on a kind of cell called a macrophage, w

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Angel, Jonathan MD, FRCPC	Senior Scientist (ICD)	HIV, Infectious disease	Basic research, Clinical research, Translational research
Cahill, Taliesin RN MSN	Clinician Investigator (ICD)	Addiction, Chronic pain, Health equity, Health in disadvantaged peoples, Hepatitis C, HIV, Infectious disease, Mental health
Cameron, Bill MD FRCPC FACP FIDSA	Senior Scientist (ICD)	Chronic obstructive pulmonary disease, COVID-19, Cystic fibrosis, HIV, Infectious disease, Sexually transmitted infections, Tuberculosis	Clinical research, Epidemiology, Immunization, Immunotherapy, Pharmacology
Cooper, Curtis MD, FRCPC	Scientist (ICD)	COVID-19, Hepatitis C, HIV, Infectious disease, Influenza	Clinical research, Immunization
Crawley, Angela Ph.D.	Senior Scientist (ICD)	Cancer, COVID-19, Hepatitis C, HIV, Infectious disease, Liver cancer, Liver disease	Basic research, Cancer immunotherapy, Clinical research, Disease models, Immunization, Immunotherapy, Molecular and cellular biology, RNA sequencing, Translational research
MacPherson, Paul PhD, MD, FRCPC	Scientist (MIR)	Anxiety, Depression, Gay men's health, HIV, Infectious disease, Men's health, Sexually transmitted infections	Behaviour, Cohort studies, Epidemiology, Health promotion, Health services research, Knowledge translation and implementation research, Prevention, Psychology, Qualitative methods, Surveys
Ramsay, Timothy PhD	Senior Scientist (MIR)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Tanphaichitr, Nongnuj PhD	Senior Scientist Emeritus (ICD)	HIV, Infectious disease, Infertility, Men's health, Sexually transmitted infections, Women's health	Basic research, Contraceptive development, Drug development, Imaging, Lipidomics, Molecular and cellular biology, Proteomics
Thavorn, Kednapa BPharm, MPharm, PhD	Senior Scientist (MIR)	Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision	Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews

Related Resources

Infectious disease research at The Ottawa Hospital

The Ottawa Hospital Immunodeficiency Clinic (HIV/AIDS)

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "HIV” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "HIV" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves.
2024-10-18

Changes in hepatic steatosis before and after direct acting antiviral treatment in people living with HIV and Hepatitis C coinfection.
2024-10-17

Comprehensive untargeted lipidomic profiling of third generation lentiviral vectors and packaging cells.
2024-10-08

Role of the pharmacist caring for people at risk of or living with HIV in Canada.
2024-09-23

Reported Side Effects and Adherence of Daily HIV Pre-Exposure Prophylaxis Users in Ontario, Canada: An Analysis of the Ontario Pre-Exposure Prophylaxis Cohort Study.
2024-09-17

Exploring Patient Viewpoints to Optimize Implementation of a Biological Therapy for Atrial Fibrillation Prevention.
2024-07-19

Willingness to receive mpox vaccine among men who have sex with men: a systematic review and meta-analysis.
2024-07-16

Associations of CD4 Cell Count Measures With Infection-Related and Infection-Unrelated Cancer Risk Among People With HIV.
2024-07-10

Breakthrough HIV viraemia on bictegravir/emtricitabine/tenofovir alafenamide in the third trimester of pregnancy.
2024-07-10

HIV pre-exposure prophylaxis and opportunities for vaccination against hepatitis A virus, hepatitis B virus and human papillomavirus: an analysis of the Ontario PrEP cohort study.
2024-06-25

View more on PubMed