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HIV

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of HIV and develop better treatments. This page includes selected news stories about our HIV research, links to researchers working in this area and related resources. Learn more below.

Research News


Meet HIV researcher Megan Magro Meet HIV researcher Megan Magro
April 25, 2022 - When she’s not doing artistic swimming, Megan Magro is in the lab working towards a cure for HIV.
Virus versus virus: novel approach shows promise against HIV in lab study Virus versus virus: novel approach shows promise against HIV in lab study
July 12, 2021 - Thanks to the development of effective drugs, HIV has become a chronic, treatable condition for most people. But it still isn’t curable, and that isn’t good enough for Dr. Jonathan Angel and his colleagues.
The Ottawa Hospital contributes to ‘a beautiful evolution’ in HIV research and care The Ottawa Hospital contributes to ‘a beautiful evolution’ in HIV research and care
December 4, 2020 - In honour of World AIDS day, we take a look back at how The Ottawa Hospital played a major role in caring for patients with HIV, how it continues to lead life-saving research, and how it is transforming how HIV is managed today.
Show more news stories


Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Angel, Jonathan
MD, FRCPC
Senior Scientist
(ICD)
HIV, Infectious disease Basic research, Clinical research, Translational research
Cahill, Taliesin
RN MSN
Clinician Investigator
(ICD)
Addiction, Chronic pain, Health equity, Health in disadvantaged peoples, Hepatitis C, HIV, Infectious disease, Mental health
Cameron, Bill
MD FRCPC FACP FIDSA
Senior Scientist
(ICD)
Chronic disease, Chronic obstructive pulmonary disease, COVID-19, Cystic fibrosis, HIV, Infectious disease, Sexually transmitted infections, Tuberculosis Clinical research, Epidemiology, Immunization, Immunotherapy, Pharmacology
Cooper, Curtis
MD, FRCPC
Scientist
(ICD)
COVID-19, Hepatitis C, HIV, Infectious disease, Influenza Clinical research, Immunization
Crawley, Angela
Ph.D.
Senior Scientist
(ICD)
COVID-19, Hepatitis C, HIV Basic research, Clinical research, Translational research
MacPherson, Paul
PhD, MD, FRCPC
Scientist
(MIR)
Anxiety, Depression, Gay men's health, HIV, Infectious disease, Men's health, Sexually transmitted infections Behaviour, Cohort studies, Epidemiology, Health promotion, Health services research, Knowledge translation and implementation research, Prevention, Psychology, Qualitative methods, Surveys
Ramsay, Timothy
PhD
Senior Scientist
(MIR)
Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Tanphaichitr, Nongnuj
PhD
Senior Scientist Emeritus
(ICD)
HIV, Infectious disease, Infertility, Men's health, Sexually transmitted infections, Women's health Basic research, Contraceptive development, Drug development, Imaging, Lipidomics, Molecular and cellular biology, Proteomics
Thavorn, Kednapa
BPharm, MPharm, PhD
Senior Scientist
(MIR)
Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews




Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "HIV” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCTTitleConditionStatusContact
NCT06032546A Study to Assess Change in Disease Activity, Adverse Events, and How the Drug Moves Through the Body in Adult Participants Living With Human Immunodeficiency Virus (HIV) Receiving Intravenous (IV) Infusion of Budigalimab and/or ABBV-382 (NCT06032546)Human Immuno-deficiency Virus (HIV) DiseaseRECRUITING 
NCT05502341Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (NCT05502341)HIV-1-infectionRECRUITING 
NCT04258475The Influence of Concurrent Oral Calcium Carbonate Supplementation on Steady State Pharmacokinetics of Oral Raltegravir. (NCT04258475)Calcium Supplementation in HIV Patients Using RaltegravirRECRUITING 
NCT03147859Vedolizumab Treatment in Antiretroviral Drug Treated Chronic HIV Infection (NCT03147859)HIV-infection/AIDSRECRUITING 


Publications

The following research publications are pulled from PubMed using the search terms "HIV" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Breakthrough HIV viraemia on bictegravir/emtricitabine/tenofovir alafenamide in the third trimester of pregnancy.
2024-07-10

HIV pre-exposure prophylaxis and opportunities for vaccination against hepatitis A virus, hepatitis B virus and human papillomavirus: an analysis of the Ontario PrEP cohort study.
2024-06-25

Correlates of Breakthrough SARS-CoV-2 Infections in People with HIV: Results from the CIHR CTN 328 Study.
2024-05-25

A Systematic Review of Oral Pre-exposure Prophylaxis HIV Adherence Interventions.
2024-04-02

Policies and practice of solid organ donation amongst people living with HIV in Canada: time for education and re-evaluation.
2024-03-26

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.
2024-03-02

Preventative behaviours and COVID-19 infection in a Canadian cohort of people living with HIV.
2023-10-20

Trends in infection-related and infection-unrelated cancer incidence among people with and without HIV infection in Ontario, Canada, 1996-2020: a population-based matched cohort study using health administrative data.
2023-10-11

Baseline characteristics of a prospective cohort study of aging and cardiovascular diseases among people living with HIV.
2023-10-02

Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART.
2023-09-07

View more on PubMed