Ottawa Hospital Research Institute

Research News

	Heavy cannabis use increases risk of developing an anxiety disorder, study suggests February 5, 2024 - Twenty-seven percent of individuals who had an emergency department visit for cannabis use developed a new anxiety disorder within three years, according to new research.
	How do developing brain blood vessels and nerves link up? New study has some answers. September 1, 2023 - Dr. Baptiste Lacoste is fascinated by how blood vessels in the brain contribute to brain and mind health.
	Researchers get $745,000 boost from NSERC May 29, 2019 - Four scientists from The Ottawa Hospital, affiliated with the University of Ottawa, were successful in the recent discovery grant competition from the Natural Sciences and Engineering Research Council of Canada (NSERC).
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	First responders to get mental health help at new research clinic October 31, 2018 - Recognizing the mental health needs of first responders, the City of Ottawa is championing a new study led by researchers at The Ottawa Hospital and the University of Ottawa. The team will launch Canada’s first research-based mental health clinic for
	The cancer’s gone but the fear remains: psychology researchers tackle fear of cancer recurrence August 16, 2018 - A pilot study by Drs. Christina Tomei, Sophie Lebel, Christine Maheu, Monique Lefebvre, and Cheryl Harris suggests that specialized psychological services could help cancer survivors manage their fear of cancer returning. While this is a realistic fe
	Extra maternal care prevents brain inflammation and reduces anxiety in mice September 22, 2017 - New research led by Dr. Hsiao-Huei Chen reveals that a protein called IRF2BP2 plays an important role in controlling anxiety in mice by influencing microglia, known as the immune system of the brain. Microglial cells can do many things, including fig
	Dr. Paul Albert recognized for ground-breaking discoveries in mental health July 11, 2017 - Dr. Paul Albert has received the top research award from the Canadian College of Neuropsychopharmacology (the Heinz Lehmann Award) for his “outstanding and innovative research” in mental health. Nearly 30 years ago, Dr. Albert performed the fir
	Drug to control appetite could also fight anxiety: Ottawa study March 5, 2015 - Did you know that our body produces its own marijuana-like compound to protect us against anxiety? A study led by Ottawa researchers published today in Neuron reveals a new biological pathway that regulates anxiety and obesity and suggests that a dru

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Albert, Paul PhD	Senior Scientist (NS)	Mental health, Vascular cognitive impairment, Anxiety, Depression, Intellectual disabilities, Parkinson's, Schizophrenia, Stroke, Suicide	Basic research, Epigenetics, Exercise, Gene expression, Translational research, Disease models, Epigenetics, Genetics, Imaging, Molecular and cellular biology, Optogenetics, Transgenic/knockout models
Arnone, Danilo MD, PhD, FRCPsych	Clinician Investigator (NS)	Anxiety, Depression, Suicide	Biomarkers, Clinical trials, Cohort studies, Epidemiology, Neuro-stimulation, Psychology, Public health
Chen, Hsiao-Huei PhD	Senior Scientist (NS)	Aging, Autism, Dementia, Depression, Heart disease, Maternal and fetal health, Mental health, Tourette's, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease	Disease models, Drug development, Gene expression, Neuro-stimulation, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Hatcher, Simon BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych	Scientist (NS)	Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide	Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Hutton, Brian MSc, PhD	Senior Scientist (MIR)	Addiction, Anxiety, Breast cancer, Depression, Health equity, Health in disadvantaged peoples, Maternal and fetal health, Mental health, Population health, Suicide, Cancer	Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Patient safety, Public health, Rapid reviews, Biostatistics, Clinical trials, Systematic reviews
MacPherson, Paul PhD, MD, FRCPC	Scientist (MIR)	Anxiety, Depression, Gay men's health, HIV, Infectious disease, Men's health, Sexually transmitted infections	Behaviour, Cohort studies, Epidemiology, Health promotion, Health services research, Knowledge translation and implementation research, Prevention, Psychology, Qualitative methods, Surveys
Poulin, Patricia C. Psych.	Associate Scientist (NS)	Addiction, Anxiety, Cancer, Chronic pain, Depression, Health equity, Musculoskeletal conditions, Pain	Anesthesiology, Behaviour, Biomarkers, Clinical research, Clinical trials, Emergency medicine, Epidemiology, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Palliative care, Patient decision aids, Patient safety, Peri-operative medicine, Pragmatic trials, Psychology, Qualitative methods, Quality Improvement, Systematic reviews
Ramsay, Timothy PhD	Senior Scientist (MIR)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Santos, Marlise MD (FRCPC), MSc, MPH	Clinician Investigator (NS)	Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Solmi, Marco MD, PhD, Psychiatrist	Clinician Investigator (NS)	Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews
Walker, Lisa PhD, C.Psych	Clinician Investigator (NS)	Anxiety, Autoimmune disease, Autoimmune diseases of the nervous system, Brain and neuromuscular disease, Dementia, Depression, Mental health, Multiple sclerosis	Behaviour, Biomarkers, Clinical research, Exercise, Imaging, Psychology, Psychometrics, Rehabilitation, Stem cells, Systematic reviews, Translational research

Related Resources

Mental health research at The Ottawa Hospital

Neuroscience Program at the Ottawa Hospital Research Institute

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Anxiety” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "Anxiety" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Efficacy and acceptability of lurasidone for bipolar depression: a systematic review and dose-response meta-analysis.
2024-11-19

Atlas of gray matter volume differences across psychiatric conditions: A systematic review with a novel meta-analysis that considers co-occurring disorders.
2024-11-04

Are Positive Biopsy Margins in Melanoma Significant?: A Cohort Study of Micro- Versus Macroscopic Margin Status and Their Impact on Residual Disease and Survival.
2024-10-09

The effect of weighted blankets on sleep quality and mental health symptoms in people with psychiatric disorders in inpatient and outpatient settings: A systematic review and meta-analysis.
2024-09-29

The Collaborative Outcome Study on Health and Functioning during Infection Times (COH-FIT): Results from Cyprus.
2024-09-28

Prevalence of schizophrenia spectrum and other psychotic disorders in problem gambling: A systematic review and meta-analysis.
2024-09-25

Dietary counseling plus omega-3 supplementation in the treatment of generalized anxiety disorder: results of a randomized wait-list controlled pilot trial (the 'EASe-GAD Trial').
2024-09-24

Safety of psychotropic medications in pregnancy: an umbrella review.
2024-09-13

Risk factors, prevention and treatment of weight gain associated with the use of antidepressants and antipsychotics: a state-of-the-art clinical review.
2024-09-03

Mental health service use among mothers and other birthing parents during the COVID-19 pandemic in Ontario, Canada.
2024-08-28

View more on PubMed