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Lab discovery suggests possible new approach for treating progressive multiple sclerosis
July 26, 2024
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A new study from The Ottawa Hospital and uOttawa shows that a microRNA molecule called miR-145-5p could be key to developing new treatments for progressive multiple sclerosis (MS).
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Study strengthens link between Epstein-Barr virus and multiple sclerosis
April 23, 2024
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“Our findings help confirm a strong relationship between MS and the Epstein-Barr virus across the lifespan, which could be a new target for treatment and prevention.”
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Can a blood test predict if MS attacks will come back after stopping treatment?
March 15, 2024
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Some people prefer to stop immune-suppressing treatment if their disease has been stable for years, but there’s no way to know whether their symptoms will return.
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New scientist profile: Dr. David Massicotte-Azarniouch aims to improve care for rare kidney diseases
May 20, 2022
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As a nephrologist specializing in glomerular diseases, Dr. David Massicotte-Azarniouch embraces the challenge of helping patients whose kidneys are being attacked by their own immune systems.
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Stem cell treatment for scleroderma improves quality of life
February 17, 2021
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When Dr. Nancy Maltez meets a patient with early severe systemic scleroderma, a rare autoimmune disease that hardens the skin and organs, she knows one of the best options is to reset their immune system using strong chemotherapy and a stem cell tran
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New scientist profile: Dr. Angela Cheung’s patients inspire her to investigate rare liver diseases
January 27, 2021
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Dr. Angela Cheung understands why her patients with autoimmune liver diseases are frustrated. Little is known about these rare diseases, and treatments can often only delay, but not prevent, a liver transplant.
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Are we using biologic therapy properly?
June 13, 2019
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The introduction of infliximab (Remicade), the first biologic therapy approved for the treatment of inflammatory bowel diseases (IBD), did not result in lower rates of hospitalizations or intestinal surgeries among patients living with IBD in Ontario
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Chance discovery linking diet to type 1 diabetes started whole new field of research
October 22, 2018
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In the early 1980's, Dr. Fraser Scott was conducting nutritional studies on rats that were supposed to develop type 1 diabetes—except they didn't. He discovered that changing the diet of these diabetes-prone rodents had prevented the disease. Making
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New blood sugar monitoring a game-changer for pregnant women with type 1 diabetes
October 24, 2017
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Fifteen women at The Ottawa Hospital took part in an international clinical trial that could change the way mothers with type 1 diabetes monitor their blood sugar levels. Mothers with this condition have a higher risk of having children with health c
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Ottawa scientist wins Canada's top stem cell prize for multiple sclerosis trial
September 6, 2017
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Dr. Harold Atkins, stem cell transplant physician and scientist at The Ottawa Hospital and the University of Ottawa, will receive the prestigious Till & McCulloch Award for “exceptional contributions to global stem cell research.” The award will
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Common acne medication shows promise in treating multiple sclerosis
June 1, 2017
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Clinical trial shows that minocycline, an oral acne medication, can slow the progress of relapsing-remitting MS
A common oral acne medication could provide new, affordable treatment options for Canadians suffering from relapsing-remitting multip
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Information for patients: Chemo and blood stem cell transplantation for rare autoimmune diseases
January 4, 2017
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A number of media stories have recently highlighted The Ottawa Hospital’s use of chemotherapy and blood stem cell transplantation to treat rare autoimmune diseases, such as myasthenia gravis, stiff person syndrome and scleroderma. These stories have
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Stem cell procedure sends patients with severe myasthenia gravis into remission
November 17, 2016
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A stem cell procedure that reboots the immune system sent seven patients with a severe form of the autoimmune disease myasthenia gravis into long-term remission, according to a retrospective study published in JAMA Neurology.
In this disease th
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MS breakthrough: Replacing diseased immune system halts progression and allows repair
June 9, 2016
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Clinical trial suggests chemo and blood stem cell combination therapy should be considered for people with early, aggressive MS
A clinical trial published in The Lancet, a top medical journal, shows that an intensive procedure that completely wipe
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The Ottawa Hospital leads first Canadian clinical trial of mesenchymal stem cell therapy for multiple sclerosis
January 29, 2015
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The Multiple Sclerosis Society of Canada and the Multiple Sclerosis Scientific Research Foundation announced today a $4.2 million grant to support the first Canadian clinical trial of mesenchymal stem cell therapy for multiple sclerosis (MS), led by
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Flu shots decrease overall risk of acquiring Guillain-Barré Syndrome
January 19, 2015
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Drs. Kumanan Wilson and Steven Hawken published a paper this week that examines whether the flu shot increases or decreases the risk of getting Guillain-Barré Syndrome (GBS), a rare but serious autoimmune condition.
Recent studies have associated
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