Ottawa Hospital Research Institute

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Musculoskeletal conditions

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of musculoskeletal conditions and develop better treatments. This page includes selected news stories about our musculoskeletal research, links to researchers working in this area and related resources. Learn more below.

Research News

	Research reveals novel mechanism controlling muscle stem cells October 5, 2022 - New research from Dr. Michael Rudnicki’s team shows for the first time that a cellular structure called a primary cilium, which functions somewhat like an antenna, plays a crucial role in priming muscle stem cells for repair and regeneration.
	Hyaluronic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle August 4, 2022 - A new study published in the journal Science reveals a unique form of cell communication that controls muscle repair.
	New scientist profile: Dr. Paul E. Beaulé aims to improve hip surgery August 18, 2021 - As an orthopedic surgeon specialized in preserving and replacing hips, Dr. Paul Beaulé has seen first-hand how these surgeries can dramatically improve his patients’ quality of life. An overarching motivation for his research is understanding wh
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	New scientist aims to harness stem cells to repair bone and cartilage July 4, 2018 - Could stem cells be harnessed to help broken bones heal faster? Could they repair damage due to osteoarthritis and sports injuries? Speed healing in people having joint replacement surgery? These are just some of the questions that Dr. Daniel Coutu w
	Stem cell researchers tackle muscle weakness in older people May 30, 2018 - For most people, muscle loss is a normal part of aging that makes daily tasks harder. Muscle loss called sarcopenia happens more quickly, leading to falls and decreased mobility. One reason for this muscle loss is that stem cells that help repair dam
	$870,000 to help develop stem cell treatments for septic shock, glaucoma, lung injury and muscle degeneration May 9, 2018 - Researchers from The Ottawa Hospital, CHEO and the University of Ottawa are bringing discoveries made in the lab closer to human trials and therapies, thanks to five new peer-reviewed research grants from the Ontario Institute for Regenerative Medi
	The Ottawa Hospital opens one-of-a-kind neuromuscular research centre May 1, 2018 - You can help!The Ottawa Hospital needs crucial equipment for neuromuscular research, including:An ultracentrifuge that separates cells into different components by spinning themat very high speed.This crucial piece of equipment can exert a force that

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Campbell, Mark MD, MSc	Clinician Investigator (Regenerative Medicine)	Bone and joint degeneration, Musculoskeletal conditions, Stroke	Basic research, Regenerative medicine, Rehabilitation, Translational research
Coutu, Daniel PhD	Scientist (Regenerative Medicine)	Aging, Arthritis, Autoimmune disease, Bleeding disorders, Blood cancer, Bone and joint degeneration, Bone and joint injuries, Chronic disease, Musculoskeletal conditions, Osteoporosis	3D printing, Basic research, Bioinformatics, Biomaterials, Cell therapy, Gene expression, Gene therapy, Genetics, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Surgery, Systems biology, Transgenic/knockout models, Translational research
Finestone, Hillel MD, FRCPC	Clinician Investigator (Clinical Epidemiology)	Chronic pain, Musculoskeletal conditions, Pain, Stroke	Rehabilitation
Lemaire, Edward PhD	Affiliate Investigator (Clinical Epidemiology)	Aging, Bone and joint degeneration, Bone and joint injuries, Concussion, Global health, Musculoskeletal conditions, Spinal cord injury, Traumatic brain injury, Traumatic injuries	3D printing, Big data, Clinical research, Clinical trials, Health research methods, Quality Improvement, Rehabilitation, Health technology
Perkins, Theodore PhD	Senior Scientist (Regenerative Medicine)	Brain and neuromuscular disease, Cancer, Muscular dystrophy, Musculoskeletal conditions, Neuromuscular disease	Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Biostatistics, Epigenetics, Gene expression, Genetics, Genomics, Proteomics, Regenerative medicine, Stem cells, Systems biology, Translational research
Poulin, Patricia C. Psych.	Associate Scientist (Clinical Epidemiology)	Addiction, Anxiety, Cancer, Chronic pain, Depression, Health equity, Musculoskeletal conditions, Pain	Anesthesiology, Behaviour, Biomarkers, Clinical research, Clinical trials, Emergency medicine, Epidemiology, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Palliative care, Patient decision aids, Patient safety, Peri-operative medicine, Pragmatic trials, Psychology, Qualitative methods, Quality Improvement, Systematic reviews
Trudel, Guy MD	Clinician Investigator (Clinical Epidemiology)	Bone and joint degeneration, Musculoskeletal conditions	Basic research, Biomarkers, Molecular and cellular biology, Regenerative medicine, Rehabilitation