Researchers
Guy Trudel

Guy Trudel

MD

Senior Scientist, Inflammation and Chronic Disease

Ottawa Hospital Research Institute

Professor of Medcine, Surgery and Biochemistry

University of Ottawa

Bone and Joint Research Laboratory

The Ottawa Hospital Rehabilitation Centre

MARROW Space Research

International Space Station Payload

Contact

gtrudel@ottawahospital.on.ca

613-737-8899 ext. 75591

ORCID 0000-0001-5254-4294

Bio

Dr. Guy Trudel runs a clinical practice and research program in Ottawa Canada. His tertiary academic rehabilitation unit delivers rehabilitation care to people after polytrauma and serious / complex medical and surgical complications.

For the past 20 years, as Director of the Bone and Joint Research Laboratory, Dr Trudel has pursued clinical and laboratory-based research on 3 areas related to the musculoskeletal complications of immobility: joint contractures, tendonopathies and fat accumulation in the bone marrow. Dr. Trudel’s Ottawa University internationally collaborative team has published over 60 original papers during his tenure, with studies supported by CIHR, Canadian, European and German Space Agencies.

Research Goals and Interests

  • Musculoskeletal effects of immobility
  • Joint contractures
  • Tendinopathies
  • Gene expression in the capsule and cartilage in contractures
  • Pannus proliferation in contractures, histomorphometric and biological study
  • Hematopoiesis with immobility

N. Caplan, M. Gruber, H. Degens, V. Abeln, G. Armbrecht, P-F. Migeotte, E. Bershad,, R. Seidler, S. Smith, A. Stahn.  G. Trudel. Joint ESA/NASA Bedrest study using Artificial Gravity as a countermeasure (AGBRESA). 2017. Co-investigator.  

G. Trudel, I. Cameron, A. Sheikh, O. Laneuville, P. Sebastiani, A. Stintzi. Bone marrow changes with long duration bedrest: Impact on target organ and personalized rehabilitation medicine. Canadian Space Agency, 2016-2019. 

G. Trudel and 15 other selected principal investigators. Life Science Research Using the Human Spaceflight Analogue “Cocktail Bed Rest study” (AO-13-BR). European Space Agency. 2016-2019. 

G. Trudel,  I. Cameron, O. Laneuville, P. Sebastiani, T. Ramsay, A. Stintzi, A. Sheikh. MARROW (Marrow Adipose Reaction: Red or White?)  Operations Phase. International Life Science Research Announcement (ILSRA) 2009 for Life Science Research on the International Space Station.  Canadian Space Agency, 2015-2021.

News

Related Research at The Ottawa Hospital