The Ottawa Hospital is conducting cutting-edge research to improve our understanding of arthritis and develop better treatments. This page includes selected news stories about our research on arthritis, links to researchers working in this area and related resources. Learn more below.
Research News
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New scientist profile: Dr. Sibel Aydin aims to personalize care for inflammatory arthritis
April 28, 2022
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Rheumatologist Dr. Sibel Aydin wants to help her patients with inflammatory arthritis return to their regular activities by giving them treatments to reduce pain and protect their joints.
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Five scientists at The Ottawa Hospital ranked among world’s top researchers
November 26, 2021
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Five scientists at The Ottawa Hospital have made it onto the prestigious list of Highly Cited ResearchersTM for 2021, with multiple papers that rank in the top one percent in their fields. Their research has been used and built upon by tens of thousa
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New scientist profile: Dr. Paul E. Beaulé aims to improve hip surgery
August 18, 2021
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As an orthopedic surgeon specialized in preserving and replacing hips, Dr. Paul Beaulé has seen first-hand how these surgeries can dramatically improve his patients’ quality of life. An overarching motivation for his research is understanding wh
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Researchers at The Ottawa Hospital awarded eight grants worth $5 million from the Canadian Institutes of Health Research
August 10, 2021
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These projects will advance science and improve health in areas such as cancer immunotherapy, orthopedic surgery, long-term care, neuromuscular disease, blood clots, vascular disease, aging, kidney disease and Inuit health.
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How well do COVID-19 vaccines work in people with cancer, immune conditions and other populations of interest?
July 15, 2021
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Researchers at The Ottawa Hospital and the University of Ottawa have been awarded more than $8 million to lead four national studies that will answer important questions about COVID-19 vaccines, including how well they work in people with cancer and
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How well do COVID-19 vaccines work in people with inherited and medication-related immune deficiencies?
July 15, 2021
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People with inherited immune deficiencies have a greater risk of developing severe COVID-19 and may be less likely to respond to vaccines. People with multiple sclerosis, arthritis and other immune-mediated diseases may also be at risk because medica
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COVID-19 and rheumatoid arthritis: using big data to understand risks and improve treatments
December 10, 2020
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Rheumatoid arthritis is an inflammatory disease that primarily affects the joints. Dr. Sibel Aydin is harnessing big data from ICES and the Ontario Best Practice Research Initiative to determine if people with rheumatoid arthritis are more or less li
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Dr. Peter Tugwell wins Barer-Flood Prize in Health Services and Policy Research
September 30, 2020
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The prize recognizes a senior researcher in the field of health services and policy research who has made a significant impact on policy research, policy and/or care delivery in Canada.
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New scientist aims to harness stem cells to repair bone and cartilage
July 4, 2018
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Could stem cells be harnessed to help broken bones heal faster? Could they repair damage due to osteoarthritis and sports injuries? Speed healing in people having joint replacement surgery? These are just some of the questions that Dr. Daniel Coutu w
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Rehabilitation researchers win national awards for work on stem cells, mobility
June 23, 2017
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Two research groups won national awards at the Canadian Association of Physical Medicine and Rehabilitation’s national conference.
Dr. Mark Campbell and his team won paper of the year* for the first study to show that the mesenchymal stem cells (
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Researchers
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Aydin, Sibel
MD
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Associate Scientist
(Inflammation and Chronic Disease)
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Arthritis, Autoimmune disease, Bone and joint degeneration, COVID-19, Population health
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Epidemiology, Imaging
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Coutu, Daniel
PhD
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Scientist
(Regenerative Medicine)
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Aging, Arthritis, Autoimmune disease, Bleeding disorders, Blood cancer, Bone and joint degeneration, Bone and joint injuries, Musculoskeletal conditions, Osteoporosis
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Basic research, Bioinformatics, Biomaterials, Cell therapy, Gene expression, Gene therapy, Genetics, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Surgery, Systems biology, Transgenic/knockout models, Translational research
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Mansour, Ramy
MSc FRCR
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Clinician Investigator
(Cancer Research)
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Arthritis, Bone and joint degeneration, Bone and joint injuries, Musculoskeletal conditions, Soft tissue sarcoma
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Artificial intelligence and data science, MRI muscle imaging
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Tugwell, Peter
O.C., MD, FRCPC
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Senior Scientist
(Methodological and Implementation Research)
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Arthritis, Global health, Population health
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Clinical research, Epidemiology, Knowledge translation and implementation research, Patient engagement, Public health, Systematic reviews
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Hepworth, Elliot
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Clinician Investigator
(Inflammation and Chronic Disease)
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Arthritis
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Ivory, Catherine
MD, PhD, FRCPC
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Senior Clinician Investigator
(Inflammation and Chronic Disease)
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Arthritis, Autoimmune disease, Lupus
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Basic research, Clinical research, Clinical trials, Cohort studies, Translational research
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Clinical Trials
The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Arthritis” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.
Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.
| NCT | Title | Condition | Status | Contact |
| NCT06454188 | A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis (NCT06454188) | Psoriatic Arthritis, Spondyloarthritis, Axial | RECRUITING | |
| NCT04080466 | Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA (NCT04080466) | Hip Dysplasia, Femoroacetabular Impingement, Osteoarthritis | RECRUITING | |
| NCT05395819 | Clinical Evaluation of Reverse Versus Anatomic Shoulder Arthroplasty Techniques in the Treatment of Osteoarthritis (NCT05395819) | Shoulder Osteoarthritis | RECRUITING | |
| NCT05543941 | Evaluating XPERIENCEâ„¢ Advanced Surgical Irrigation (NCT05543941) | Hip Osteoarthritis, Hip Arthritis, Knee Osteoarthritis, Knee Arthritis | RECRUITING | |
| NCT05601427 | Intra-Operative Adductor Canal Blocks (NCT05601427) | Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Anesthesia | RECRUITING | |
| NCT04580225 | Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE) (NCT04580225) | Wrist Arthritis, Wrist Arthropathy, Scapholunate Advanced Collapse, Scaphoid Nonunion, Post-traumatic; Arthrosis, Arthritis, Musculoskeletal Diseases, Joint Diseases | RECRUITING | |
| NCT02966886 | TSA Techniques in Glenohumeral OA (NCT02966886) | Osteoarthritis, Shoulder | RECRUITING | |
| NCT05487274 | TSA v RSA in Osteoarthritic Shoulders With Greater Than 15 Degrees of Retroversion (NCT05487274) | Osteoarthritis Shoulder | RECRUITING | |
| NCT04228419 | TSA vs RSA in Glenohumeral Osteoarthritis (NCT04228419) | Osteoarthritis of the Shoulder | RECRUITING | |
