StemCore Laboratories
Recent Publications
Journal Articles, Theses and preprints that acknowledge StemCore's contributions
2025
Akuma, M. (2025). Characterization of Dysregulated VHL-Mediated pRb Regulation in Clear Cell Renal Cell Carcinoma [PhD Thesis, Université d’Ottawa/University of Ottawa].
Aller à la publicationClémot-Dupont, S., Lourenço Fernandes, J. A., Larrigan, S., Sun, X., Medisetti, S., Stanley, R., El Hankouri, Z., Joshi, S. V., Picketts, D. J., Shekhar, K., & Mattar, P. (2025). The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis. Proceedings of the National Academy of Sciences, 122(3), e2405981122.
Aller à la publicationCober, N. D., McCourt, E., Godoy, R. S., Deng, Y., Schlosser, K., Qamsari, E. S., Azami, J., Salehisiavashani, E., Cook, D. P., & Lemay, S.-E. (2025). Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension. Cardiovascular Research, 121(13), 2095–2112.
Aller à la publicationEsper, M. E., Lin, A. Y., Bennett, D., & Rudnicki, M. A. (2025). Intrinsic dysfunction in muscle stem cells lacking dystrophin begins during secondary myogenesis. Nature Communications, 16(1), 10031.
Aller à la publicationJahan, S., Maganti, H. B., Patel, J., Pasha, R., Doxtator, E., Manesia, J. K., & Pineault, N. (2025). Reduction in cord blood graft potency due to processing delay can be prevented by trehalose supplementation. Vox Sanguinis, vox.70012.
Aller à la publicationJo, D.-H. (2025). Innovative Approaches to Natural Killer Cell Engineering: Overcoming Challenges in CRISPR-Cas9 Genome Editing, Transgene Expression, and Cryopreservation [PhD Thesis, Université d’Ottawa/University of Ottawa].
Aller à la publicationJo, D.-H., Kaczmarek, S., Khan, A. U. H., Pervin, J., Clark, D. M., Gadde, S., Wang, L., McComb, S., Visram, A., & Lee, S.-H. (2025). Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression. Frontiers in Immunology, 16, 1533044.
Aller à la publicationLarrivée, M. (2025). Generating CAR γδ T Cells for Effective Targeting of B Lymphomas [PhD Thesis, Université d’Ottawa| University of Ottawa].
Aller à la publicationLosier, T. T., King, K. E., Rousseaux, M. W., & Russell, R. C. (2025). Identification of organelle-specific autophagy regulators from tandem CRISPR screens. Journal of Cell Biology, 224(10), e202405138.
Aller à la publicationMartell, E., Kuzmychova, H., Senthil, H., Chawla, U., Kaul, E., Grewal, A., Banerji, V., Anderson, C. M., Venugopal, C., & Miller, D. (2025). Disease stage-specific role of the mitochondrial pyruvate carrier suppresses differentiation in temozolomide and radiation-treated glioblastoma. Neuro-Oncology, noaf008.
Aller à la publicationNoblett, N. (2025). Exploring the Role for IPPK-1 and PAL-1 in the Genetic Landscape of C. elegans Ventral Nerve Cord Assembly [PhD Thesis, Université d’Ottawa| University of Ottawa].
Aller à la publicationNoblett, N., Roenspies, T., Flibotte, S., & Colavita, A. (2025). Nuclear hormone receptor regulation of Caudal mediates ventral nerve cord assembly in C. elegans. bioRxiv
Aller à la publicationParweez, F., Palou, R., Li, R., Kadhim, L., MacMillan, H., Tyers, M., & Johné Liu, X. (2025). Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster. bioRxiv
Aller à la publicationShah, S., Lourenço Fernandes, J. A., Medisetti, S., & Mattar, P. (2025). Chd4 remodels chromatin to control retinal cell type specification and lineage termination. bioRxiv
Aller à la publicationZuccarini, R. (2025). The Effect of Sox9 on Cell Growth and Stemness in HER2-Positive Breast Cancer [PhD Thesis, Université d’Ottawa/University of Ottawa].
Aller à la publication2024
Angka, L., Tennakoon, G., Cook, D. P., Martel, A. B., Market, M., de Souza, C. T., Cummins, E., Samudio, I., Kekre, N., & Ardolino, M. (2024). Preventing surgery induced immune suppression and metastases by inhibiting PI3K-gamma signalling in Myeloid-Derived Suppressor Cells. bioRxiv
Aller à la publicationBergin, C. J., Zouggar, A., Mendes da Silva, A., Fenouil, T., Haebe, J. R., Masibag, A. N., Agrawal, G., Shah, M. S., Sandouka, T., Tiberi, M., Auer, R. C., Ardolino, M., & Benoit, Y. D. (2024). The dopamine transporter antagonist vanoxerine inhibits G9a and suppresses cancer stem cell functions in colon tumors. Nature Cancer.
Aller à la publicationBhattarai, K. R. (2024). Deciphering the Role of ARK5 and hnRNP A1 in Regulating the Osmotic Stress. [PhD Thesis, Carleton University].
Aller à la publicationClemot-Dupont, S., Fernandes, J. A. L., Larrigan, S., Sun, X., Medisetti, S., Stanley, R., El Hankouri, Z., Joshi, S. V., Picketts, D. J., & Shekhar, K. (2024). The ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers. bioRxiv
Aller à la publicationCyr-Depauw, C., Cook, D. P., Mižik, I., Lesage, F., Vadivel, A., Renesme, L., Deng, Y., Zhong, S., Bardin, P., Xu, L., Möbius, M. A., Marzahn, J., Freund, D., Stewart, D. J., Vanderhyden, B. C., Rüdiger, M., & Thébaud, B. (2024). Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells. American Journal of Respiratory and Critical Care Medicine.
Aller à la publicationGatica, D., Alsaadi, R. M., El Hamra, R., Mueller, R., Miyazaki, M., Sad, S., & Russell, R. (2024). The ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection. bioRxiv
Aller à la publicationKalinina, A. (2024). The Differential Regulation of Adult Neural Stem Cells by Beclin1 and Atg5 [PhD Thesis, Université d’Ottawa/University of Ottawa].
Aller à la publicationKalinina, A., Dhaliwal, J., Xue, Y., Vaculik, M., McCambley, M., Fong, B. C., Cook, D., Slack, R. S., & Lagace, D. C. (2024). Mitotic Activity and DNA Maintenance of Adult Neural Stem Cells is Regulated by Beclin1. bioRxiv
Aller à la publicationKornfeld, S. F., Cummings, S. E., Yaworski, R., De Repentigny, Y., Gagnon, S., Zandee, S., Fathi, S., Prat, A., & Kothary, R. (2024). Loss of miR-145 promotes remyelination and functional recovery in a model of chronic central demyelination. Communications Biology, 7(1), 813.
Aller à la publicationLeung, J. W.-H., Loan, A., Xu, Y., Yang, G., Wang, J., & Chan, H. M. (2024). Reduction of Glyoxalase 1 Expression Links Fetal Methylmercury Exposure to Autism Spectrum Disorder Pathogenesis. Toxics, 12(7), Article 7.
Aller à la publicationLi, J., Vranjkovic, A., Read, D., Delaney, S. P., Stanford, W. L., Cooper, C. L., & Crawley, A. M. (2024). Lasting differential gene expression of circulating CD8 T cells in chronic HCV infection with cirrhosis identifies a role for Hedgehog signaling in cellular hyperfunction. Frontiers in Immunology, 15.
Aller à la publicationLoan, A., Awaja, N., Lui, M., Syal, C., Sun, Y., Sarma, S. N., Chona, R., Johnston, W. B., Cordova, A., & Saraf, D. (2024). Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms. Theranostics, 14(16), 6110.
Aller à la publicationLosier, T. T., Rousseaux, M. W., & Russell, R. C. (2024). Identification of stress specific autophagy regulators from tandem CRISPR screens. bioRxiv
Aller à la publicationMolyer Yildirir, B. (2024). SMAC Mimetics Sensitize HIV-Infected Cells to MG1-Mediated Death [PhD Thesis, Université d’Ottawa | University of Ottawa].
Aller à la publicationPeneycad, C. J. (2024). The splicing inhibitor isoginkgetin induces transcription of metallothionein genes through the metal responsive transcription factor MTF-1 [PhD Thesis, Carleton University].
Aller à la publicationProwse, N. (2024). The Truncated Tropomyosin Kinase B Receptor Influences Feeding Behaviour, Cholesterol Production and Susceptibility to Stress in a Sex-Dependent Manner [PhD Thesis, Carleton University].
Aller à la publicationPrykhozhij, S. V., Ban, K., Brown, Z. L., Kobar, K., Wajnberg, G., Fuller, C., Chacko, S., Lacroix, J., Crapoulet, N., & Midgen, C. (2024). miR-34a is a tumor suppressor in zebrafish and its expression levels impact metabolism, hematopoiesis and DNA damage. PLoS Genetics, 20(5), e1011290.
Aller à la publicationRodriguez, G. M., Yakubovich, E., Maranda, V., Hanna, A. M. R., & Vanderhyden, B. C. (2024). NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens. Frontiers in Immunology, 14.
Aller à la publicationRussell, R., Akuma, M., Kim, M., Zhu, C., Wiljer, E., Gaudreau-Lapierre, A., Patterson, L., Trinkle-Mulcahy, L., Stanford, W. L., & Riazalhosseini, Y. (2024). Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma. bioRxiv
Aller à la publicationSuk, T. R., Part, C. E., Nguyen, T. T., Zhang, J. L., Heer, M. M., Caballero-Gomez, A., Grybas, V. S., McKeever, P. M., Nguyen, B., & Callaghan, S. M. (2024). A stress-dependent TDP-43 SUMOylation program preserves neuronal function. bioRxiv
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