Ottawa Hospital Research Institute

Research News

	Blood removal before major liver surgery cuts transfusions in half December 9, 2024 - Removing 10 per cent of a patient’s blood before major liver surgery and giving it back afterwards reduced transfusions by half, according to a large clinical trial published in The Lancet Gastroenterology & Hepatology.
	Blood transfusions for brain bleeding: Large trial in aneurysmal subarachnoid hemorrhage patients adds to debate about optimal threshold December 9, 2024 - Blood is one of the oldest drugs in the world, but after many decades of research, it is still not always clear when a blood transfusion should be given. A large trial published in the New England Journal of Medicine is adding to the debate for patie
	When can a critically ill patient breathe on their own? Trial compares approaches November 27, 2024 - “We want to see patients in the ICU breathing on their own as soon as possible, and this trial identified some promising avenues to explore."
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	New Canada Research Chairs to advance regenerative medicine, thrombosis and stroke research at The Ottawa Hospital November 14, 2024 - The federal government announced a new round of Canada Research Chairs this week, including three based at The Ottawa Hospital.
	New solutions needed to reduce blood loss during bladder removal surgery November 5, 2024 - "This study proves that routine use of tranexamic acid is not effective, so we need to explore other options."
	Physiotherapists get patients moving early in international ICU cycling trial August 27, 2024 - “There’s considerable evidence that early mobility is the best thing we can contribute to a patient’s recovery, and in-bed cycling can be another great tool to accomplish this with certain patients."
	When research inspires care: Patient partners spearhead brain aneurysm recovery guide July 23, 2024 - Survivors of brain aneurysms and their family members are the driving force behind a new guide for patients at The Ottawa Hospital on what to expect when recovering from this kind of stroke.
	Researchers at The Ottawa Hospital awarded 14 CIHR grants worth more than $10 million July 18, 2024 - “Success at CIHR underscores the creativity, dedication and collaboration of our researchers and their teams. Funding for these innovative projects paves the way for groundbreaking advancement in biomedical sciences, improved patient care and progres
	Specialized therapy helps teacher with traumatic brain injury make remarkable recovery July 2, 2024 - “We’ve been really active in brain injury and trauma research and this study was brought here to truly provide the best care possible to our patients.”
	Researchers at The Ottawa Hospital awarded three grants for high risk, high reward and interdisciplinary research June 18, 2024 - The New Frontiers in Research Fund (NFRF) 2023 Exploration competition has awarded $33 million to support 133 research teams across Canada that bring diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
	Are EVs travelling to injured lungs? March 15, 2024 - Tiny particles called extracellular vesicles (EVs) released by mesenchymal stem cells (MSCs) have shown clear potential to treat several lung diseases in animal models by reducing inflammation. However, there has been debate about where MSC-EVs end u
	ELEVATE seed grants to help researchers at The Ottawa Hospital improve treatment for inflammatory and immune conditions February 21, 2024 - The Ottawa Hospital’s Research Institute is awarding four ELEVATE seed grants to help researchers understand the role of inflammation and the immune system in various diseases and develop better treatments.
	Researchers at The Ottawa Hospital awarded 9 CIHR grants worth more than $5 million February 2, 2024 - Researchers at The Ottawa Hospital are leading nine new projects funded by the Canadian Institutes of Health Research (CIHR) through the most recent operating grant and SPOR innovative clinical trial competitions.
	Made-in-Ottawa AI tool could help critically ill patients February 1, 2024 - An innovative tool developed by researchers at The Ottawa Hospital is closer to helping critically ill patients following its approval by Health Canada.
	New scientist profile: Dr. Yan Xu aims to better understand blood clots in racialized populations January 2, 2024 - “Our first step is to understand if there are ethnic and racial differences in the prevention and treatment of blood clots in Canada. And if so, what we can do about it.”
	Do anesthesiology consults before surgery improve patient outcomes? December 6, 2023 - More patients are seeing an anesthesiologist before surgery as the surgical population ages and faces more complex health issues.
	Powering up the body’s EVs November 9, 2023 - Dr. Alvin Tieu is receiving the Worton Researcher in Training Award from The Ottawa Hospital for his multidisciplinary research on life-threatening lung diseases
	Meet Dr. Edward Clark, The Ottawa Hospital’s new Jindal Research Chair for the Prevention of Kidney Disease September 28, 2023 - As The Ottawa Hospital’s new Jindal Chair for Kidney Disease Prevention, Dr. Clark will be able to accelerate his research, which aims to help more critically ill patients survive acute kidney injury, and recover enough kidney function to avoid dialy
	Researchers at The Ottawa Hospital awarded 13 CIHR grants worth more than $7 million July 21, 2023 - Researchers at The Ottawa Hospital are playing a lead role in 13 new projects awarded more than $7 million from the Canadian Institutes of Health Research (CIHR).
	Will I be on dialysis forever? New calculator could help kidney disease patients June 9, 2023 - People who receive their first kidney dialysis treatment during a hospital admission often wonder if their kidneys will eventually recover, or if they will need to continue dialysis for the rest of their lives. A new calculator developed by Dr. Edwar
	CT scan results help predict which mini-strokes lead to major strokes June 8, 2023 - This is the first study to confirm the additional risk of stroke related to these findings. It also suggests that adding these CT findings to TIA decision tools would further improve physicians’ ability to predict a patient’s future stroke risk and p
	Exercise before surgery? This cancer survivor is a believer April 4, 2023 - Find out why he credits a “prehab” study for his quick recovery
	Routine preoperative medical consultations don’t improve surgery outcomes March 27, 2023 - A large observational study published in JAMA Internal Medicine suggests that most patients do not medically benefit from consultation with a medical specialist before their surgery.
	Moving the needle forward on sepsis research with a world-first clinical trial March 16, 2023 - The search for the silver bullet for sepsis has been decades in the making. However, The Ottawa Hospital is taking a big step forward in the next phase of a world-first clinical trial using stem cells in patients with septic shock.
	Meet Dr. Manoj Lalu, the clinician-scientist bringing lab discoveries to patients every day March 16, 2023 - From looking at how we can use stem cells to treat diseases like sepsis to dealing with patients directly in the ICU and OR, Dr. Lalu is making an impact behind the scenes and beyond.
	Meet Dr. Lauralyn McIntyre — sepsis researcher and clinician extraordinaire March 16, 2023 - Dr. Lauralyn McIntyre’s path to The Ottawa Hospital wasn’t necessarily a direct one — it took her all over Ontario and out west to the mountains — but she couldn’t do her groundbreaking sepsis research anywhere else, or with any other team.
	Researchers at The Ottawa Hospital awarded 15 CIHR grants worth more than $8.4 million February 3, 2023 - Researchers at The Ottawa Hospital are playing a lead role in 15 new projects awarded more than $8.4 million from the Canadian Institutes of Health Research (CIHR).
	ELEVATE seed grants to help researchers at The Ottawa Hospital develop better treatments and improve patient care February 1, 2023 - The Ottawa Hospital’s Research Institute is awarding five ELEVATE seed grants to early-career researchers to spur the development of innovative treatments and better patient care.
	Why more patients are taking a front seat in medical research January 27, 2023 - After undergoing surgery herself, Gurlie Kidd was so interested in work on a team studying “prehabilitation” for frail patients undergoing surgery, that she got involved.
	Researchers at The Ottawa Hospital co-lead $39M Accelerating Clinical Trials (ACT) Consortium January 19, 2023 - The new Accelerating Clinical Trials (ACT) Consortium, co-led by The Ottawa Hospital, aims to transform Canada’s clinical trials landscape by removing barriers, streamlining approvals, enhancing support and facilitating the engagement and participati
	Clinical trial will test promising cell therapy for septic shock January 19, 2023 - Dr. Lauralyn McIntyre was awarded $1.6 million from the Canadian Institutes of Health Research Clinical Trials Fund to conduct a Phase II clinical trial of mesenchymal stem cells (MSCs) in patients with septic shock.
	When a heart won’t start, some defibrillation strategies work better than others January 11, 2023 - A randomized controlled trial published in the New England Journal of Medicine found that two different defibrillation strategies were associated with increased survival among out-of-hospital cardiac arrest patients whose hearts didn’t start after st
	Intravenous vitamin C treatment does not help sepsis patients December 14, 2022 - A randomized controlled trial published in the New England Journal of Medicine has quashed the theory that intravenous vitamin C could prevent death and organ damage in patients with sepsis.
	Does “prehab” before surgery improve patient outcomes? Pilot sets the stage for national trial October 5, 2022 - A home-based prehabilitation or “prehab” program designed to help older adults with frailty recover from cancer surgery has shown promise in a randomized pilot trial, particularly for patients who had a high level of adherence to the program.
	“Dream team” of researchers tackles leading cause of vision loss July 27, 2022 - Dr. Catherine Tsilfidis has assembled a world-class team to bring discoveries with game-changing potential to patients with retinal disease
	Researchers at The Ottawa Hospital awarded 19 CIHR grants worth more than $12 million July 20, 2022 - These projects will advance science and improve health in areas such as cancer, neuroscience, regenerative medicine, autism, Kabuki Syndrome, kidney disease, patient engagement, blood transfusions, sepsis, surgery, anesthesia, plasma donation, muscle
	Ottawa-led team develops AI-enabled model to diagnose birth defect in fetal ultrasound images July 14, 2022 - Artificial intelligence is poised to play a truly transformative role in global health care. The convergence of medicine and AI might eventually prove to be more impactful than the unraveling of the genome.
	First made-in-Canada CAR-T cell therapy for cancer shows promise in clinical trial June 17, 2022 - More than a dozen people with cancer who had exhausted all treatment options are alive and cancer-free today thanks to a pioneering Canadian clinical trial of a highly personalized kind of immunotherapy.
	Ottawa Hospital researchers awarded $1.85M from Stem Cell Network May 12, 2022 - Four research teams at The Ottawa Hospital have been awarded a total of $1.85 million to harness stem cells and regenerative medicine to develop new therapies for septic shock, bone and joint conditions, and newborn lung damage, while also advancing
	Study fills knowledge gaps about surgery outcomes for Inuit in Canada May 3, 2022 - A team of Canadian researchers, including Inuit and other Indigenous researchers, have published the first study of Inuit surgical outcomes today in CMAJ Open.
	Ottawa researchers contribute to three important studies shaping COVID-19 care April 28, 2022 - Researchers from The Ottawa Hospital continue to play a key role in influential COVID-19 research, with three studies recently published in top-tier journals.
	Researchers at The Ottawa Hospital awarded five grants for high risk, high reward and interdisciplinary research April 4, 2022 - The New Frontiers in Research Fund (NFRF) 2021 Exploration competition has awarded $25 million to support 102 research teams across Canada that bring diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
	New scientist profile: Dr. Edward Clark aims to improve kidney health for hospitalized patients March 17, 2022 - As a nephrologist who sees patients in the ICU, Dr. Edward (Ted) Clark knows kidneys can often stop working when someone is critically ill.
	Survivors and families help set priorities for out-of-hospital cardiac arrest research February 17, 2022 - Survivors, families, bystander responders and healthcare providers were part of an inclusive process to set international priorities for out-of-hospital cardiac arrest research.
	Tiny particles hold promise for treating acute and chronic lung disease February 17, 2022 - A meta-analysis of lab studies found that tiny particles called extracellular vesicles (EVs) released by mesenchymal stem/stromal cells (MSCs) have clear potential for treating acute lung injury,
	Study explores patient engagement in lab research January 6, 2022 - A study found that engaging patients in laboratory research is possible, and can benefit both the patients and the researchers.
	Virtual care with remote monitoring catches drug errors and reduces patient pain November 4, 2021 - The use of take-home technology by patients following non-elective surgery resulted in significantly greater detection and correction of drug errors, and reduced pain, according to a study published in The BMJ.
	$2.4 M grant to help researchers develop gene and cell therapies for a leading cause of blindness September 15, 2021 - A team led by Dr. Catherine Tsilfidis has received $2.4 M from the Ontario Research Fund to develop treatments for retinal diseases, a leading cause of blindness.
	Outpatient clinic linked to 40% decrease in return ED visits for cellulitis September 8, 2021 - Cellulitis, a common bacterial skin infection, accounts for 3% of all ED visits. Patients with severe cases that need intravenous (IV) antibiotics are normally admitted to hospital or must return to the ED several times to receive the multiple doses
	Nothing about me, without me: Engaging patients in clinical trials August 13, 2021 - It seems obvious – blindingly so – that patients, traditionally the subjects of clinical trials, should be involved as partners from the beginning. The benefits for patients are clear – an increased sense of control and the ability to learn about the
	Researchers honoured for outstanding work in anesthesiology, blood disease and cancer June 4, 2021 - A number of outstanding researchers and research teams have been honoured through The Ottawa Hospital’s Excellence Awards program for 2021.
	Researchers at The Ottawa Hospital awarded three grants for high risk, high reward and interdisciplinary research May 31, 2021 - The New Frontiers in Research Fund (NFRF) 2020 Exploration competition brings diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
	Hold the ice: study shows no benefit during kidney cancer surgery May 19, 2021 - A clinical trial shows that contrary to popular belief, renal hypothermia doesn’t actually improve kidney function after kidney cancer surgery.
	Canadian researchers work to understand and improve health for Indigenous Peoples after surgery May 17, 2021 - Researchers at The Ottawa Hospital and the University of Ottawa are building a research program to better understand Indigenous Peoples’ experience of surgery in Canada. Their latest study, published in CMAJ, is the first to analyze all available sur
	Experts on call: How to survive and thrive after a medical emergency April 22, 2021 - Ever wonder what goes on behind the scenes in the emergency department (ED)? At The Ottawa Hospital, research plays a huge role in both enhancing patient care and making the ED more efficient.
	Grateful COVID-19 patient gives back by participating in research April 13, 2021 - Sharon Charlebois doesn’t remember much about the 25 days she spent at The Ottawa Hospital fighting a severe case of COVID-19 in January 2021. Now that she’s recovering at home with her husband, some memories come back to her in flashes.
	Researchers at The Ottawa Hospital awarded 17 CIHR grants worth $7.5 million March 10, 2021 - Researchers at The Ottawa Hospital are playing a lead role in 17 new projects funded by the Canadian Institutes of Health Research (CIHR).
	One small step for blood cancer patients, one giant step for Canadian cancer patients of all stripes February 25, 2021 - The Canadian-Led Immunotherapies in Cancer (CLIC) research program is building Canada’s capacity for innovation in CAR-T therapy, with support from BioCanRx, The Ottawa Hospital, BC Cancer and the Ontario Institute for Cancer Research
	Sepsis costs Ontario healthcare system $1 billion per year February 22, 2021 - A study published in Critical Care Medicine led by researchers at The Ottawa Hospital, the University of Ottawa, and ICES shows that severe sepsis is linked with higher mortality, increased hospital readmission and higher healthcare costs. In Ontario
	When Is Dead Really Dead? February 17, 2021 - Researchers at The Ottawa Hospital played a major role in a CHEO-led study published in the New England Journals of Medicine. The study, led by Dr. Sonny Dhanani, asked over 600 families to allow their loved ones in the ICU to have their vital signs
	App provides patients with their personalized risks after surgery February 17, 2021 - Patients who used a made-in-Ottawa app to calculate their risk of complications, hospitalization and death after surgery understood these risks better than patients who received standard care, according to a study published in the Canadian Journal of
	Tool predicts which mini-strokes could lead to major strokes February 3, 2021 - A made-in-Ottawa tool can help emergency physicians predict which patients with mini-strokes are at greatest risk of having a major stroke within the week, according to a study published in The BMJ.
	Experimental stem cell therapy a potential weapon against COVID-19 February 1, 2021 - Drs. Duncan Stewart, Shane English, Dean Fergusson and colleagues have launched a clinical trial to test MSCs in people with severe COVID-19.
	Understanding the impact of COVID-19 on women December 30, 2020 - Dr. Innie Chen is leading research to understand the impact of COVID-19 on women, thanks to seed funding through The Ottawa Hospital Foundation’s COVID-19 Emergency Response Fund.
	Spinal or epidural anesthesia associated with increased survival compared to general anesthesia for leg artery bypass surgery November 25, 2020 - A new study published in The BMJ shows that people who had surgery to improve blood flow in their legs under spinal or epidural anesthesia were less likely to die than those who were given general anesthesia. General anesthesia involves using drugs t
	Blueprint Excelerator helps move discoveries from the bench to the bedside November 6, 2020 - The Blueprint Translational Research Group was established in 2016 at The Ottawa Hospital, in collaboration with the Ottawa Methods Centre. Co-led by Dr. Dean Fergusson and Dr. Manoj Lalu, Blueprint developed an innovative model called the Excelerato
	New scientist profile: Dr. Lisa Caulley aims to find the best care for ear, nose and throat disorders October 21, 2020 - Dr. Lisa Caulley aims to help her colleagues make the best care decisions for ear, nose and throat disorders. New techniques and treatments are constantly being developed to treat these complex conditions, but it is not always clear which will work b
	The Ottawa Hospital and uOttawa launch new cancer immunotherapy research projects with funding from BioCanRx September 22, 2020 - BioCanRx, Canada’s Immunotherapy Network, today announced funding of $10M for 14 cancer immunotherapy research projects and eight core and biomanufacturing facilities across the country. Researchers at The Ottawa Hospital (TOH) and the University of
	How to mitigate ICU drug shortages related to COVID-19 September 9, 2020 - As COVID-19 continues to disrupt global drug supplies, researchers at The Ottawa Hospital are playing a key role in developing and implementing mitigation strategies for intensive care units (ICUs).
	The Ottawa Hospital awarded six CIHR grants worth $2.6 million September 7, 2020 - Could a common diabetes drug help prevent ovarian cancer? Can a tailored screening program help prevent eye disease in immigrants? Is sepsis different in females versus males, and if so, can this help us develop better treatments? These are just a fe
	Two researchers at The Ottawa Hospital receive Ontario Early Researcher Awards September 1, 2020 - Two researchers from The Ottawa Hospital affiliated with the University of Ottawa received Early Researcher Awards from the Ontario Research Fund.
	Cannabis use in pregnancy linked to a greater risk of autism August 10, 2020 - In the largest study of its kind, researchers from The Ottawa Hospital, BORN Ontario and the University of Ottawa found that children whose mothers reported using cannabis during pregnancy were at greater risk of autism.
	Hyperbaric oxygen therapy for COVID pneumonia June 26, 2020 - Astudy led by Dr. Sylvain Boet will test if hyperbaric oxygen therapy may be able to help some people with COVID-19 pneumonia.
	The Ottawa Hospital awarded $4.7 million for COVID-19 research from the Canadian Institutes of Health Research June 25, 2020 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $4.7 million from the Canadian Institutes of Health Research (CIHR) for four research projects that could transform our understanding of COVID-19 and lead
	TOHAMO awards $1.2M for COVID-19 research projects June 12, 2020 - Could artificial intelligence help predict which COVID-19 patients will become gravely ill? Could a home-based spit test diagnose COVID-19? Could virtual care after surgery reduce patient returns to hospital?
	Can virtual care after surgery reduce patient returns to hospital? Research study now open in Ottawa June 10, 2020 - COVID-19 has accelerated the adoption of all kinds of virtual health care, from phone and video appointments to tools that monitor symptoms remotely. The Ottawa Hospital continues to be at the forefront of this trend with the launch of an innovative
	Creating a new mouse model to study COVID-19 lung disease June 4, 2020 - Researchers are working to develop a mouse model of COVID-19 that mimics the severe lung disease seen in humans. The lack of good, accessible animal models of this disease is severely limiting research around the world.
	When is fainting a sign of a bigger problem? This tool can tell May 14, 2020 - Most of the time fainting is harmless, but for some people it can be caused by serious conditions like irregular heartbeat. A made-in-Ottawa tool can accurately tell emergency physicians which patients will have symptoms of these serious conditions
	Updated Ottawa Rules app could help doctors predict strokes, catch deadly brain bleeds May 14, 2020 - A free app for emergency department physicians based on Ottawa’s world-renowned clinical decision rules has added more rules to its roster.
	Harnessing stem cells and regenerative medicine to fight COVID-19 April 23, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa have been awarded $490,000 from the Stem Cell Network for two research projects that could help in the fight against COVID-19. These peer-reviewed grants are part of an overall investm
	Researchers join the fight against COVID-19 April 2, 2020 - As hospitals and communities band together to fight COVID-19, researchers at The Ottawa Hospital are harnessing their unique expertise and resources to help.
	Assisted reproductive technology and heart problems: it’s (mostly) about the twins February 24, 2020 - Babies born through Assisted Reproductive Technology (ART) like in vitro fertilization have a small but significantly increased risk of being born with heart problems (2.2 percent for ART babies compared to 1.2 percent for non-ART babies). Now, a new
	Pilot project allows Ottawa paramedics to provide palliative care at home February 19, 2020 - A pilot project led by emergency medicine researchers at The Ottawa Hospital and the University of Ottawa, in partnership with the Ottawa Paramedic Service, will give eligible palliative care patients the option of being treated at their home for pai
	The Ottawa Hospital awarded nine grants worth $5.6 million from Canadian Institutes of Health Research February 3, 2020 - How can we treat depression when nothing else is working? How can heart growth be both good and bad? How can we increase patient participation in clinical trials? These are just a few of the big questions that researchers at The Ottawa Hospital will
	Intravenous drugs can often rapidly restore normal heart rhythm without sedation, shocks January 30, 2020 - A study published in The Lancet found that two ways of quickly restoring normal heart rhythm in patients with acute atrial fibrillation in the emergency department are equally safe and effective.
	To help protect research, experts agree on a definition of predatory publishing January 15, 2020 - Leading scholars and publishers from The Ottawa Hospital’s Centre for Journalology, the University of Ottawa’s Telfer School of Management, and other institutions from around the world have agreed on a consensus definition of predatory publishing.
	Ottawa doctor recognized as one of the top emergency medicine researchers in Canada January 7, 2020 - Dr. Venkatesh Thiruganasambandamoorthy has received a major honour recognizing his outstanding contributions to advancing care in the emergency department both in Canada and around the world. He is the winner of the 2020 Mid-Career Lecturer Award in
	New scientist profile: Dr. Krishan Yadav aims to improve care for skin infections December 11, 2019 - Dr. Krishan Yadav wants to find the best way to treat the patients with skin infections he sees in the emergency department. Currently there is little evidence on how best to treat common skin infections such as cellulitis.
	How likely are you to survive in-hospital cardiac arrest? Newly identified risk factors can help with difficult decisions December 4, 2019 - A paper published in the BMJ is the first to identify risk factors that affect patient survival after in-hospital cardiac arrest. This new information can help patients, families and care providers decide on their care goals upon admission to hospita
	Researchers awarded $1.6M to improve care for cardiovascular disease November 13, 2019 - The Heart and Stroke Foundation of Canada has awarded $1.6M to researchers at The Ottawa Hospital, affiliated with the University of Ottawa.
	aSAH survivor and her daughter help advance stroke research October 23, 2019 - When 61-year-old Debi Borbridge had an aSAH, a rare form of stroke, little did she know that two years later she and her daughter would be helping to shape the future of research in this field.
	Milestone study will help doctors treat life threatening blood clots October 22, 2019 - Faizan Khan’s research will influence how doctors around the world treat venous thrombosis, the third-deadliest cardiovascular disease. This is a remarkable achievement for a PhD candidate in the early stages of his career.
	Ottawa a “hotbed of patient partnerships in research” September 27, 2019 - The Ontario SPOR Support Unit’s summer newsletter showcases how Ottawa has become a “hotbed of patient partnerships in research.” Three stories demonstrate how researchers at The Ottawa Hospital are partnering with patients and caregivers to improve
	Thinking about using cannabis during pregnancy? Think again. September 16, 2019 - New research suggests that pregnant women who use cannabis have a greater risk of a preterm birth.
	New research chair to lead cutting-edge work in liver and pancreatic cancer September 10, 2019 - The Ottawa Hospital and the University of Ottawa are pleased to announce the appointment of Dr. Guillaume Martel as the first Arnie Vered Family Chair in Hepato-Pancreato-Biliary Research.
	The promise of CAR-T therapy for cancer: meta-analysis shows the big picture August 14, 2019 - CAR-T therapy, which uses a patient’s own genetically modified immune cells, is one of the most exciting advances in cancer treatment. To get a big picture view of the field, Drs. Manoj Lalu and Dean Fergusson led a team that analyzed data from nearl
	Research could improve diagnosis of dangerous increase in brain pressure August 8, 2019 - Increased pressure in the brain due to swelling or bleeding is a complication of brain injury that can cause additional damage and even death. A study led by researchers from The Ottawa Hospital and the University of Ottawa found that no single non-i
	Study establishes long-term risks and consequences of leg vein clot recurrence July 31, 2019 - Over 750,000 Canadians will have an unexplained vein blood clot in their lifetime, known as venous thrombosis. A collaborative study led by Dr. Marc Rodger and Faizan Khan now provides the best data yet on the long-term risks and consequences of recu
	The Ottawa Hospital awarded 13 grants worth $11.2 million from Canadian Institutes of Health Research July 26, 2019 - Researchers at The Ottawa Hospital have been awarded 13 grants worth a total of $11.2 million from the Canadian Institutes of Health Research (CIHR). The new projects focus on areas such as cancer immunotherapy, hepatitis C infection, blood clots, ar
	Cannabis use in pregnancy linked to increased risk of preterm birth June 19, 2019 - Researchers from The Ottawa Hospital, CHEO, BORN Ontario and the University of Ottawa have conducted one of the largest studies to date on the effect of cannabis use during pregnancy. They found that reported cannabis use during pregnancy was associa
	Golfer credits Ottawa study for quick recovery after lung cancer surgery June 4, 2019 - Marie Lapointe took part in a pilot study at The Ottawa Hospital aimed at testing whether a home-based exercise program could help older people better prepare for surgery
	$950,000 to help develop stem cell treatments for septic shock, lung injury and muscle degeneration May 17, 2019 - Researchers from The Ottawa Hospital, CHEO and the University of Ottawa are bringing discoveries made in the lab closer to human trials and therapies, thanks to four new peer-reviewed research grants from the Ontario Institute for Regenerative Medici
	Clinical trials offer strong foundation for better patient care May 16, 2019 - Clinical trials are an important step toward developing new treatments and learning more about diseases and conditions. In honour of International Clinical Trials Day, read how some of the researchers at The Ottawa Hospital are making huge contribut
	Researchers honoured for outstanding work in Parkinson’s, critical care and surgery April 11, 2019 - A number of outstanding researchers and research teams were recognized at The Ottawa Hospital’s Excellence Awards Ceremony on April 11. They include the Parkinson Research Consortium, the Operating Room Black Box® Research Program and ICU resear
	Clinicians at The Ottawa Hospital launch 14 innovative projects to improve health-care delivery, thanks to funding from TOHAMO and The Ottawa Hospital’s Research Institute March 22, 2019 - The Ottawa Hospital Academic Medical Organization (TOHAMO) has awarded $1.169 million in Innovation Grants to 14 teams, with supporting funds provided by the Ottawa Hospital Research Institute.
	Patients and clinical trial experts key to upcoming made-in-Canada CAR-T clinical trial March 1, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa are known around the world for their expertise in designing and leading clinical trials, and they're now applying this knowledge to create a made-in-Canada approach for CAR-T cell cl
	Researchers use leading-edge technology to study teamwork and communication in the operating room February 15, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa are studying whether improving teamwork and communication among operating room staff can make surgery safer for patients. Studies suggest that over half of surgery complications can be l
	Researchers to advance science and improve health with new CIHR funding February 14, 2019 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, are playing a lead role in nine new projects funded by the Canadian Institutes of Health Research (CIHR). These projects will advance science and improve health in areas su
	How long do people need to be monitored after fainting? January 21, 2019 - For the first time, physicians in the Emergency Department (ED) have evidence-based recommendations on how best to catch the life-threatening conditions that make some people faint. New research published in Circulation suggests that low-risk patient
	Drug dramatically reduces risk of dangerous blood clots in cancer patients December 4, 2018 - A Canadian clinical trial published in the New England Journal of Medicine provides the first approach for safely preventing blood clots (or venous thromboembolism) in people with cancer. About half of people newly diagnosed with a solid cancer coul
	Decision tool identifies which patients with COPD are at risk of death, serious complications December 3, 2018 - A made-in-Ottawa decision tool can help emergency physicians identify which patients with chronic obstructive pulmonary disease are at high risk of serious complications including death. The Ottawa COPD Risk Scale is better than current practice at p
	Engaging patients in research every step of the way November 28, 2018 - CMAJ's new supplement on engaging patients in health research features commentaries led by Drs. Dean Fergusson, Simon Hatcher and Christian Vaillancourt, as well as 14 other teams affiliated with Ontario’s SPOR SUPPORT Unit (OSSU). As co-Scientific D
	Made-in-Ottawa rule helps patients with neck injuries in the emergency department October 17, 2018 - A study led by Dr. Ian Stiell found that triage nurses in the emergency department can safely use a made-in-Ottawa rule to make wait times shorter and more comfortable for patients who have neck pain after a fall or car collision. Due to a very small
	High dose folic acid does not prevent preeclampsia in high-risk women September 12, 2018 - Taking high doses of folic acid throughout pregnancy does not prevent preeclampsia in high-risk women, according to a large international clinical trial published in The BMJ. This refutes the findings of previous observational studies and is expected
	Not sure if you can give good CPR? New data shows you probably can August 7, 2018 - Bystanders who come to the aid of someone whose heart has stopped are performing high-quality CPR that consistently meets the latest guidelines, according to a study led by Drs. Shannon Fernando, Christian Vaillancourt and Ian Stiell. Fifteen percen
	$1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss July 20, 2018 - Four research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $1.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). Their projects will advance sci
	Urologists reduce unnecessary prostate cancer surgery in Eastern Ontario July 5, 2018 - A growing number of patients in Eastern Ontario are being saved from unnecessary prostate cancer surgeries, according to a study led by Dr. Luke Lavallée and Dr. Luke Witherspoon published in CMAJ Open. While prostate cancer is the most common cancer
	Top Research Papers from The Ottawa Hospital 2015-2017 June 7, 2018 - Did you know that researchers at The Ottawa Hospital publish an average of four new scientific papers every single day? Our research is advancing science and improving health on a massive scale – both at home and around the world. The list below repr
	The Ottawa Hospital Emergency Surgery Study: A World Leader in the Delivery of High Quality and Efficient Surgical Care July 10, 2017 - Researchers at The Ottawa Hospital and the University of Ottawa are tackling the often-overlooked issue of delayed emergency surgeries. Emergency surgeries are those needed quickly to treat serious injuries or life-threatening conditions, such as a
	Researcher aims to make surgery safer for frail patients September 29, 2016 - Anesthesiologist and scientist Dr. Daniel McIsaac is doing research to better understand why some older patients recover quickly after surgery while others do not. As Canada’s population ages, more older patients are coming to hospital for sur
	Virus vs. Prostate Cancer: Canadian Researchers Pioneer Next-generation Therapy -- Prostate Cancer Canada and the Movember Foundation partner to make innovative work possible September 30, 2015 - A multi-disciplinary team of scientists and clinicians led by Dr. John Bell of The Ottawa Hospital is developing a treatment for prostate cancer using viruses that destroy cancer cells and boost the anti-cancer immune response, all the while leaving

Scientists

Scientists have PhDs, MDs or both and devote at least 40 per cent of their time to research (but typically more than 75 per cent). All our Scientists also hold appointments at the University of Ottawa and many are active clinicians at The Ottawa Hospital. Scientists generally hold major peer-reviewed research grants and work with a team of graduate students, postdoctoral fellows, technicians and coordinators.

Investigators

Clinician Investigators are generally physicians, nurses, or other health professionals at The Ottawa Hospital who devote between 5 and 40 per cent of their time to clinical research. They often also hold appointments at the University of Ottawa. Investigators are generally PhD researchers with several years of postdoctoral training who devote between 20 and 50 per cent of their time to research.

Affiliate Investigators

Affiliate Investigators are researchers who have primary affiliations with other institutions, but maintain significant collaborations or funding with the Ottawa Hospital Research Institute.