Johné Liu

Contact Information

Johné Liu, PhD
613-737-8899 x 72906
jliu@ohri.ca

Faith Izevbizua
fizevbizua@ohri.ca

https://orcid.org/0000-0003-3381-5030

ORCID logo https://orcid.org/0000-0003-3381-5030

What We Do

Selected Publications

Parweez F, Marin RP, Li R, McMillan H, Tyers M, and Liu XJ. Engineered spermidine- secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster. Frontiers in Neuroscience Volume 19 - 2025 | https://doi.org/10.3389/fnins.2025.1628160 (2025)

Mohaqiq M, Marin RP, Li R, Zhang G, Vaishnav, H, Parweez P, Moyana T, Carragher D, Cameron DW, Ramsay T, van der Sloot A, Murthy S, Coombes B, Tyers M, and Liu XJ. Engineered spermidine-overproducing Saccharomyces boulardii ameliorates colitis and colon cancer in mice. Scientific Reports https://doi.org/10.1038/s41598-025-16736-5 (2025)

Lavergne CLJ, Tao Y, Ren Y, Lafleur N, Liu XJ. Systemic L-ornithine supplementation specifically increases ovarian putrescine levels during ovulation in mice. Biol Reprod 106:792-801 (2022).

Mo G, Ruizhen Li, Zachary Swider, Julie Leblanc, William M. Bement and X. Johné Liu. A localized calcium transient and polar body abscission. Cell Cycle. ePublished. https://doi.org/10.1080/15384101.2022.2092815 (2022).

Li R, Ren Y, Mo G, Swider Z, Mikoshiba K, Bement WM, and Liu XJ. Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in Xenopus oocytes. Mol. Biol. Cell epublished. https://www.ncbi.nlm.nih.gov/pubmed/36129775 (2022)

Tao Y, Tartia A, Lawson M, Zelinski M, Wu W, Liu J-Y, Smitz J, Leveille M-C, Leader A, Wang H, Ramsay T, Liu XJ. . Peri-ovulatory putrescine supplementation to improve egg quality in older infertile women. J. Assist Reprod Genet 36:395-402 (2019)

Li R, Leblanc J, He K, and Liu XJ. Calcium chelators cause rapid depolymerization of spindle microtubules and inhibit polar body emission in Xenopus oocytes. Mol. Biol. Cell. 27:3273-3283 (2016)

Tao Y, Liu D, Mo G, Wang H, and Liu XJ. Peri-ovulatory putrescine supplementation reduces embryo resporption in older mice. Human Reproduction 30: 1867-75 (2015).

Tao Y, and Liu XJ. Deficiency of ovarian ornithine decarboxylase contributes to aging-related egg aneuploidy in mice. Aging Cell. 12:42-49 (2013)

Shao H, Li R, Ma C, Chen E, and Liu XJ. Xenopus oocyte meiosis lacks spindle assembly checkpoint control. J. Cell Biol. 201:191-200 (2013)

Meet the LIU Lab