Bladder cancer

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of bladder cancer and develop better treatments. This page includes selected news stories about our bladder cancer research, links to researchers working in this area and related resources. Learn more below.

Research News


New solutions needed to reduce blood loss during bladder removal surgery New solutions needed to reduce blood loss during bladder removal surgery
November 5, 2024 - "This study proves that routine use of tranexamic acid is not effective, so we need to explore other options."


Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Morgan, Scott
MD, MSc, FRCPC
Clinician Investigator
(CR)
Bladder cancer, Breast cancer, Cancer, Prostate cancer Biomarkers, Clinical research, Clinical trials, Cohort studies, Imaging, Systematic reviews




Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Bladder cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCTTitleConditionStatusContact
NCT06129084A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing (NCT06129084)Metastatic Bladder Cancer, Metastatic Urothelial CarcinomaRECRUITING 
NCT04260802A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers (NCT04260802)Cancer, Neoplasms, Metastatic Cancer, Triple Negative Breast Cancer, Gastric Cancer, Cervical Cancer, Ovarian Cancer, Hepatocellular Carcinoma, Squamous Cell Carcinoma of Head and Neck, Urothelial Carcinoma, Urothelial Neoplasm, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Locally Advanced Solid Tumor, Locally Advanced Malignant Neoplasm, Squamous Cell Carcinoma, Sarcoma, Merkel Cell Carcinoma, Bladder CancerRECRUITING 
NCT04574960Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) (NCT04574960)Bladder Cancer, Bladder Urothelial CarcinomaRECRUITING 
NCT04543110Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC (NCT04543110)Bladder CancerRECRUITINGcaproulx@ohri.ca


Publications

The following research publications are pulled from PubMed using the search terms "Bladder cancer" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Benefit of Whole-Pelvis Radiation for Patients With Muscle-Invasive Bladder Cancer: An Inverse Probability Treatment Weighted Analysis.
2024-10-04

Tranexamic Acid During Radical Cystectomy: A Randomized Clinical Trial.
2024-10-02

Effect of Complete Transurethral Resection on Oncologic Outcomes After Radiation Therapy for Muscle-Invasive Bladder Cancer.
2024-08-27

The Impact of Histologic Subtypes on Clinical Outcomes After Radiation-Based Therapy for Muscle-Invasive Bladder Cancer.
2024-07-26

Thromboprophylaxis during neoadjuvant chemotherapy for bladder cancer reduces thromboembolism and bleeding.
2024-07-04

Benefit of Neoadjuvant Cisplatin-based Chemotherapy for Invasive Bladder Cancer Patients Treated with Radiation-based Therapy in a Real-world Setting: An Inverse Probability Treatment Weighted Analysis.
2024-02-08

Radiation-based Therapy for Muscle-invasive Bladder Cancer: Contemporary Outcomes Across Tertiary Centers.
2023-04-03

A survey of physician perception and practices regarding pharmacological thromboprophylaxis during chemotherapy for bladder cancer.
2022-05-28

Venous thromboembolism risk in patients receiving neoadjuvant chemotherapy for bladder cancer.
2022-05-18

Intravesical immunotherapy with a GM-CSF armed oncolytic vesicular stomatitis virus improves outcome in bladder cancer.
2022-03-02

View more on PubMed