Megeney Lab

Destruction as a creative process: CAD-induced DNA strand breaks promote macrophage differentiation

SMCHD1 activates the expression of genes required for the expansion of human myoblasts

Regulatory Mechanisms That Guide the Fetal to Postnatal Transition of Cardiomyocytes

Caspase 3 exhibits a yeast metacaspase proteostasis function that protects mitochondria from toxic TDP43 aggregates

Self-inflicted DNA breaks in cell differentiation and cancer

Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress

JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment

Right Ventricular Maladaptation to Pressure Overload in Fischer Rats Is Associated With Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics

Chromatin Reorganization during Myoblast Differentiation Involves the Caspase-Dependent Removal of SATB2

MLIP causes recessive myopathy with rhabdomyolysis, myalgia and baseline high serum creatine kinase.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases