Core Facilities and Platforms

Biotherapeutics Manufacturing Centre (BMC)

Biotherapeutics Manufacturing Centre (BMC)

Products and services

BMC will develop and produce therapeutics based on viruses, cells and antibodies for clients in academia and the pharmaceutical industry.

Products include:

  • Oncolytic viruses.

  • Viral vectors for gene and cell therapy.

  • Vaccines.

  • Mesenchymal stem cells.

  • Somatic cells.

  • Genetically-enhanced stem/progenitor cells.

Services include:

  • Innovation services that will expand the knowledge base on virus and cell manufacturing.

  • Upstream and downstream process development.

  • New assay development and assay qualification/validation services.

  • cGMP manufacturing of clinical-scale virus products, cell banks, and individualized cell therapies.

  • Development and execution of validated SOPs for clinical sample processing in accordance with the ICH Q2 guidelines.

  • Stability and storage programs.

  • Client cell line storage.

  • GMP manufacturing of Master Cell Bank.

  • Creation of viral master seed bank.

  • Manufacturing process development, optimization and validation.

  • Purification process development and optimization.

  • Pilot virus batch manufacturing.

  • GMP virus clinical lot manufacturing (bulk drug substance, drug product).

  • Manufacturing and quality documentation (and regulatory support as needed).

  • Co-development of virus-based therapeutics.