Cook Lab

Loss of Sox10 prevents tumor initiation in vivo and induces luminal-to-basal reprogramming in Neu+ tumor cells

Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets

Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension

LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCs

FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models

Aneuploidy drives the acquisition of cancer-specific driver genes

Chromatin Remodelling in Damaged Intestinal Crypts Orchestrates Redundant TGFβ and Hippo Signalling to Drive Regeneration

Transcriptional regulation of the postnatal cardiac conduction system heterogeneity

Transcriptional Regulation of the Postnatal Cardiac Conduction System Heterogeneity

The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells

PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma