Cook Lab

Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets

Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension

LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCs

Chromatin remodelling in damaged intestinal crypts orchestrates redundant TGFβ and Hippo signalling to drive regeneration

Aneuploidy drives the acquisition of cancer-specific driver genes

Transcriptional regulation of the postnatal cardiac conduction system heterogeneity

Transcriptional Regulation of the Postnatal Cardiac Conduction System Heterogeneity

The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells

Preventing surgery induced immune suppression and metastases by inhibiting PI3K-gamma signalling in Myeloid-Derived Suppressor Cells

PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway

Chromatin Remodelling in Damaged Intestinal Crypts Orchestrates Redundant TGFβ and Hippo Signalling to Drive Regeneration