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The Ottawa Hospital awarded six CIHR grants worth $2.6 million

Could a common diabetes drug help prevent ovarian cancer? Can a tailored screening program help prevent eye disease in immigrants? Is sepsis different in females versus males, and if so, can this help us develop better treatments?

These are just a few of the big questions that researchers at The Ottawa Hospital will try to answer with six new project grants from the Canadian Institutes of Health Research (CIHR), worth a total of $2.6 million.

"Research projects such as these will help us provide the best care possible for our patients and community, while advancing science and improving health on a global scale," said Dr. Duncan Stewart. "I'm proud that The Ottawa Hospital has consistently ranked as one of the top hospitals in the country for highly-competitive CIHR funding, ranking fourth overall in 2019-20."

The new grants include:

Comparison of Bleeding Risk between Rivaroxaban and Apixaban in Atrial Fibrillation (COBRRA AF) 

  • Principal Investigators: Castellucci, Lana; Le Gal, Grégoire; Perry, Jeffrey J; de Wit, Kerstin
  • Co-Investigators: Ramsay, Timothy O; Hibbert, Benjamin M; Thavorn, Kednapa; Stiell, Ian G; Healey, Jeff S; Kovacs, Michael J; Birnie, David H; Schulman, Sam; Parkash, Ratika; Shivakumar, Sudeep P; Kahn, Susan R; Solymoss, Susan; Blostein, Mark D; Campbell, Samuel G
  • Amount: $100,000

Sex differences in preclinical models of sepsis: a systematic review

  • Principal Investigators: Lalu, Manoj M; Liaw, Patricia C; McDonald, Braedon A; Macala, Kimberly; Fiest, Kirsten M; Fergusson, Dean A; Gill, Sean E; Fox-Robichaud, Alison E
  • Co-Investigators: Mendelson, Asher A; Welsh, Donald G; Veldhuizen, Rudolf A; Vazquez-Grande, Gloria; Stewart, Duncan J; Medeiros, Sarah K; Lehmann, Christian; Cepinskas, Gediminas; Arora, Jaskirat; Kristof, Arnold S; Ellis, Christopher G; Winston, Brent W; Charbonney, Emmanuel; Mawdsley, Laura; Bourque, Stephane; Marshall, John C; Tieu, Alvin; Sharma, Neha; Sohrabipour, Sahar; Cailhier, Jean-Francois; Zhang, Haibo; Kubes, Paul; Zarychanski, Ryan
  • Amount: $112,500

Preventing blindness by going to where you are: Culturally-competent tele-retina programs to support newcomers to attend diabetic retinopathy screening

  • Principal Investigators: Presseau, Justin; Dogba, Maman A; Brent, Michael H
  • Co-Investigators: Grimshaw, Jeremy M; McCleary, Nicola; Lawrenson, John G; Ivers, Noah M; Witteman, Holly M; Boucher, Marie-Carole; McHugh, Sheena; Thavorn, Kednapa; Yu, Catherine
  • Amount: $637,398

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT) 

Evaluating the palliative and end-of-life care of older Canadians living and dying with dementia 

  • Principal Investigators: Tanuseputro, Peter; Hsu, Amy T
  • Co-Investigators: Kyeremanteng, Kwadwo; Bush, Shirley; Downar, James; Isenberg, Sarina R; Lawlor, Peter G; Manuel, Douglas G; Maxwell, Colleen J; Webber, Colleen; Fitzgibbon, Edward J; Howard, Michelle I; Quinn, Kieran L
  • Amount: $378,675

Reducing ovarian cancer risk by regulating age-associated ovarian fibrosis

  • Principal Investigator: Vanderhyden, Barbara C
  • Co-Investigators: Trudel, Dominique; Strickland, Sarah; Jacobson, Michelle R
  • Amount: $680,850

These projects are supported by core research resources at The Ottawa Hospital, such as the Ottawa Methods Centre and ICES uOttawa.

Learn how you can support research at The Ottawa Hospital and make a difference for patients in Ottawa and around the world.

The Ottawa Hospital is a leading academic health, research and learning hospital proudly affiliated with the University of Ottawa.   

Media Contact 
Amelia Buchanan
Senior Communication Specialist
Ottawa Hospital Research Institute
613-297-8315
ambuchanan@ohri.ca

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The Ottawa Hospital is a leading academic health, research and learning hospital proudly affiliated with the University of Ottawa and supported by The Ottawa Hospital Foundation.