Directory

Ovarian cancer

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of ovarian cancer and develop better approaches for treatment and prevention. This page includes selected news stories about our ovarian cancer research, links to researchers working in this area and related resources. Learn more below.


Labs and Groups

These research teams may include multiple scientists, investigators, staff and trainees all working towards a common goal, or they can represent a single scientist and their team.

Gray line-style icon of a microscope.
Research Group
Ardolino Cancer Immunology Lab
Why don't the Killers kill? Understanding the immune system to develop better immunotherapy The immune system is an incredible weapon against...
Research Group
Auer Lab
The Auer Lab makes use of both preclinical and clinical research to understand the mechanisms responsible for the prometastatic effects of surgery ...
Research Group
Cook Lab
Treatment options for ovarian cancer are limited, and while tumours often respond to initial treatments, many recur and become resistant to therapy...
Research Group
Ilkow Lab
Findings from our research will provide new light on the role of the tumour microenvironment during virus-based therapies and could contribute to t...
Gray line-style icon of a microscope.
Research Group
Tsang Lab
We study ovarian follicular growth, female infertility, ovarian cancer biology, chemoresistance, placental biology and more.
Research Group
Vanderhyden Lab
Determining how risk factors contribute to ovarian cancer initiation and progression, single cell analyses and bioinformatics to investigat...
Michele Ardolino
Scientist

Michele Ardolino

Senior Scientist, Cancer Research
Rebecca Auer
Scientist

Rebecca Auer

Senior Scientist, Cancer Research
David Cook
Scientist

David Cook

Scientist, Cancer Research
Carolina Ilkow
Scientist

Carolina Ilkow

Senior Scientist, Cancer Research
Shahidul Islam
Clinician Investigator

Shahidul Islam

Clinician Investigator, Cancer Research
Timothy Ramsay
Scientist

Timothy Ramsay

Senior Scientist, Methodological and Implementation Research
Benjamin Tsang
Emeritus

Benjamin Tsang

Senior Scientist Emeritus, Inflammation and Chronic Disease
Barbara Vanderhyden
Scientist

Barbara Vanderhyden

Senior Scientist, Cancer Research

Clinical Trials

The following list of clinical trials at The Ottawa Hospital is pulled from ClinicalTrials.gov, which is hosted by the U.S. National Library of Medicine and only available in English. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. If you email the study team directly, we can guarantee a response. Learn more about participating in research and clinical trials.

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers (NCT04260802)
Cancer, Neoplasms, Metastatic Cancer, Triple Negative Breast Cancer, Gastric Cancer, Cervical Cancer, Ovarian Cancer, Hepatocellular Carcinoma, Squamous Cell Carcinoma of Head and Neck, Urothelial Carcinoma, Urothelial Neoplasm, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Locally Advanced Solid Tumor, Locally Advanced Malignant Neoplasm, Squamous Cell Carcinoma, Sarcoma, Merkel Cell Carcinoma, Bladder Cancer View Details

Publications

The following research publications from The Ottawa Hospital are pulled from PubMed, with publication date of 2020 or later. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Circulating plasma gelsolin and MRI-based radiomics as biomarkers of platinum resistance in epithelial ovarian cancer: building a multiparameteric prediction algorithm.

2025-11-25 Go to publication

Global DNA methylation signatures associated with chemoresistance and poor prognosis of high grade serous ovarian cancer.

2025-10-22 Go to publication

P53 Mutation Induces Epithelial-to-Mesenchymal Transition (EMT) Associated with Stem Cell Properties and Tumorigenesis in Fallopian Tube Cells.

2025-10-14 Go to publication

Specific Genetic Mutations Impact Chemotherapy Resistance and Therapeutic Efficacy of Oncolytic Viruses in Ovarian Cancer.

2025-10-01 Go to publication

Cancer genetics and response to oncolytic virus treatment for ovarian cancer.

2025-09-01 Go to publication
View More on PubMed