Directory

Amyotrophic lateral sclerosis

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of amyotrophic lateral sclerosis (ALS) and develop better treatments. This page includes selected news stories about our ALS research, links to researchers working in this area and related resources. Learn more below.


Labs and Groups

These research teams may include multiple scientists, investigators, staff and trainees all working towards a common goal, or they can represent a single scientist and their team.

Research Group
Kothary Lab
Our laboratory is interested in understanding the mechanisms which maintain/alter muscle and nervous system integrity. In parallel, we are assess...
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Research Group
Sachs Lab
We investigate how real-time feedback of brain signals can be used to help individuals with movement disorders. Using brain-computer interface (BCI...
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Clinician Investigator

Matti Allen

Clinician Investigator, Neuroscience
Santanu Chakraborty
Clinician Investigator

Santanu Chakraborty

Senior Clinician Investigator, Neuroscience
Rashmi Kothary
Scientist

Rashmi Kothary

Senior Scientist, Regenerative Medicine
Tiago Mestre
Scientist

Tiago Mestre

Scientist, Neuroscience
John Ngsee
Affiliate

John Ngsee

Affiliate Investigator, Neuroscience
Timothy Ramsay
Scientist

Timothy Ramsay

Senior Scientist, Methodological and Implementation Research
Adam Sachs
Scientist

Adam Sachs

Associate Scientist, Neuroscience
Jodi Warman Chardon
Scientist

Jodi Warman Chardon

Associate Scientist, Neuroscience

Publications

The following research publications from The Ottawa Hospital are pulled from PubMed, with publication date of 2020 or later. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Amyotrophic Lateral Sclerosis Clinical Research Site Operations: Emerging Challenges and Potential Solutions From Multiple Sites in the US.

2026-01-01 Go to publication

Toward therapeutic trials in primary lateral sclerosis.

2025-11-01 Go to publication

Variability across versions of the self-administered ALSFRS-R: a review and call for harmonization.

2025-11-01 Go to publication

Sedating with volatile anaesthetics for COVID-19 and non-COVID-19 acute hypoxaemic respiratory failure patients in ICU (SAVE-ICU): protocol for a randomised clinical trial.

2025-10-13 Go to publication

Atypical features including acquired oculomotor apraxia in C9orf72-associated familial primary lateral sclerosis.

2025-09-26 Go to publication
View More on PubMed

Resources

Neuroscience Program at the Ottawa Hospital Research Institute

Search for clinical trials at The Ottawa Hospital related to this disease or condition.