Rashmi Kothary
Ph.D.
Senior Scientist, Regenerative Medicine
Ottawa Hospital Research Institute
Professor, Medicine
University of Ottawa
Professor, Cellular and Molecular Medicine
University of Ottawa
Contact
613-737-8707
Lab Tel: 613-739-6634; Heidi Hickey (Research Administrative Assistant) 613-737-8899 x72794, hhickey@,ohri.ca
Research Groups
Kothary Lab
Bio
Dr. Kothary is a Senior Scientist at the Ottawa Hospital Research Institute (OHRI) and has served as OHRI’s Deputy Scientific Director since 2012. He received a PhD in Biochemistry from the University of British Columbia and pursued postdoctoral research in the laboratories of Dr. Janet Rossant at the Mount Sinai Hospital Research Institute in Toronto and Dr. Azim Surani in Cambridge, U.K. It was during these formative years that Dr. Kothary developed his interests in pre-clinical models to study disease pathology. He has held the University Health Research Chair in Neuromuscular Disorders and is a Professor at the University of Ottawa. His current research focuses on investigating factors important for oligodendrocyte mediated myelination and remyelination of the CNS (in the context of Multiple Sclerosis) and understanding Spinal Muscular Atrophy pathogenesis to identify novel therapeutics for this devastating children’s disease. He currently sits on the SMA Beyond advisory board and on the scientific advisory board for RHU SMART (France), MDA and Cure SMA, and is a reviewer for the CIHR, NIH, Shriners Hospitals, MS Soc, and MDC.
News
Publications
Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology
2025-02-20 Go to publicationImpact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology
2025-02-20 Go to publicationImpact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology
2025-02-10 Go to publicationSMN depletion impairs skeletal muscle formation and maturation in a mouse model of SMA
2025-01-23 Go to publicationPeripheral defects precede neuromuscular pathology in the Smn 2B/− mouse model of spinal muscular atrophy
2024-11-01 Go to publicationRelated Research at The Ottawa Hospital
- Regenerative Medicine Program
- Neuromuscular disease
- Amyotrophic lateral sclerosis
- Multiple sclerosis
- Muscular dystrophy
- Spinal muscular atrophy
- Discovery research
- Drug development
- Gene therapy
- Genetics
- Imaging
- Lipidomics
- Model organisms
- Molecular and cellular biology
- Proteomics
- Regenerative medicine
- Translational research
- Epigenetics
- Transgenic/knockout models
- Disease models