Stuart Nicholls

Stuart Nicholls

BSc(Hons), MSc, MRes, PhD

Scientist, Methodological and Implementation Research

Ottawa Hospital Research Institute

Scientist, Methodological and Implementation Research Program

Ottawa Hospital Research Institute

Contact

613-737-8899 x73822

Centre for Practice-Changing Research, General Campus, 501 Smyth Road, Ottawa, ON K1H 8L6

Administrative Coordinator: Jodi Peters: jpeters@ohri.ca 613-737-8899 x79842

Bio

I completed my PhD degree in Applied Social Statistics at Lancaster University, Lancaster, UK in 2010. My PhD thesis focused on parental experiences of consent to newborn bloodspot screening through a mixed methods approach using qualitative interviews and surveys that were analysed using structural equation modelling techniques. In addition, I hold MRes in Social Statistics, an MSc in Healthcare Ethics, and a BSc (Hons) in Genetics. 

I am currently a Scientist in the Methodological and Implementation (MIR) program at the Ottawa hospital research Institute, having previously been the program lead for the Office for Patient Engagement in Research Activities (OPERA) since September 2020. Prior to joining the OHRI, I was a Methodologist within the Clinical Research Unit at the Children’s Hospital of Eastern Ontario (CHEO) Research Institute and completed a CIHR-funded postdoctoral fellowship at the School of Epidemiology and Public Health, University of Ottawa.

As an applied researcher in patient engagement and a member of the Ottawa Methods Centre and OPERA, I work with researchers across specialities to support patient engagement in their research whether it is a systematic review, survey, priority setting exercise, or clinical trial. To date I have published over 130 peer reviewed publications, a co-authored monograph, and half a dozen book chapters. I have been a principal applicant, co-applicant, or collaborator on 86 funded research studies totalling over $77 Million. In addition, I have previously been a member of the Canadian Clinical Trials Coordinating Centre (CCTCC)/Health Canada working group on developing a pan-Canadian accreditation system for Research Ethics Boards reviewing clinical trials and was a member of the Health Canada/Public Health Agency of Canada Research Ethics Board. 
 

Research Goals and Interests

  • Patient engagement in research
  • Health Services Research
  • Ethical challenges in research
  • Methods development in research
  • Implementation of health research methods and practices

The main focus of my work is patient engagement in health research - the active collaboration with patients, families, caregivers or communities in governance, priority setting, developing the research questions, and even performing certain parts of the research itself. My research falls within four main areas, all of which aim to improve the methods and implementation of patient engagement in research:

1. Understanding and/or explaining what influences implementation outcomes: e.g. barriers and facilitators to engagement in research (including use of resources) & building solutions.

2. Describing the processes and practices of engagement in research (esp. underserved areas & focus on equity)

3. Conducting ethical analyses of engaging with people with lived experience (PWLE) and communities in research (research ethics and ‘everyday ethics’)

4. Improving the evidence base and quality of engagement and evaluating the implementation of patient engagement


These goals are achieved by combining research with practice through the Office for Patient Engagement in Research Activities (OPERA), which provides consultation services, training, and resources for teams wishing to engage patients, families, or caregivers as partners in research. 


News


Publications

Patient and Public Involvement in Paediatric Pragmatic Randomized Controlled Trials: A Mixed Methods Study

2025-12-02 Go to publication

Efficacy, all-cause discontinuation, and safety of serotonergic psychedelics and MDMA to treat mental disorders: A living systematic review with meta-analysis

2025-12-01 Go to publication

Identifying challenges and enablers to engaging patients in preclinical laboratory research: an interview study.

2025-11-28 Go to publication

Health Service Utilization in Children With Permanent Hearing Loss: A Nested Case Control Study.

2025-11-25 Go to publication

Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial.

2025-11-11 Go to publication

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