Researchers
Yan Xu

Yan Xu

MD, FRCPC, MSc

Associate Scientist, Inflammation and Chronic Disease

Ottawa Hospital Research Institute

Hematologist, Department of Medicine

The Ottawa Hospital

Assistant Professor, Department of Medicine

University of Ottawa

Contact

yaxu@toh.ca
ORCID 0000-0001-7429-4724
@IMYanXu

Bio

Dr. Xu obtained his medical degree at Queen’s University (Kingston), followed by internal medicine residency at the University of Toronto. He moved to Ottawa in 2019 to complete his hematology residency, followed by an Adult Thrombosis Medicine fellowship and a Master of Science degree in Epidemiology.

He joined the OHRI in July 2023 and is an attending hematologist and thrombosis specialist at The Ottawa Hospital.

Research Goals and Interests

Anticoagulant safety; Venous thromboembolism; Health disparities; Thrombotic conditions in racialized populations.

Dr. Xu's research program seeks to optimize the risks and benefits of anticoagulants in the prevention and treatment of arterial and venous thromboembolism among racialized populations, with aims to characterize, understand, and address systemic inequities across the spectrum of thrombosis research and clinical care. His active areas of inquiry include: 

1. Anticoagulant-associated bleeding in racialized populations

2. Racial equity in pregnancy-associated venous thromboembolism

3. Perspectives on thrombosis diagnosis, management and research participation among underrepresented ethnoracial communities

News

Publications

Cardiac thrombus despite anticoagulation in a 76-year-old man

2025-11-17 Go to publication

Racial Disparities in the Incidence and Risk Factors for Major Bleeding during Extended Anticoagulant Therapy for Venous Thromboembolism.

2025-08-04 Go to publication

Factors associated with COVID-19 vaccine confidence among Arab, Asian, Black, Indigenous, and White individuals in Canada: Latent profile analyses

2025-08-01 Go to publication

Racial disparities related to the perception of COVID-19 vaccine effectiveness among parents of children aged 0-12 years old in Canada.

2025-07-23 Go to publication

Impact of clonal hematopoiesis of indeterminate potential on arterial atherothrombosis and venous thromboembolism: Protocol for a systematic review and meta-analysis

2025-07-16 Go to publication
View More on ORCiD

Principal Applicant:

1. Racial Disparities in the Diagnostic Management and Outcomes of Pregnancy-associated Venous Thromboembolism: A Population-based Observational Study (International Society on Thrombosis and Haemostasis Grant Program)

2. Optimizing the Prevention of Symptomatic Venous Thromboembolism among Medical Inpatients (Health Data Research Network Canada)

3. Anti-Xa Guided Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism Following Traumatic Injury: A Pilot Randomized Trial (University of Ottawa Department of Medicine Pilot Research Grant)

4. Barriers and facilitators to venous thromboembolism research participation in underrepresented ethnoracial groups (CIHR Planning and Dissemination Grant – Institute of Circulatory and Respiratory Health)

5. Patient preferences for oral anticoagulants in venous thromboembolism among underrepresented ethnoracial groups: a qualitative interview study (University of Ottawa TOGETHER Social Accountability Grant)

6. Effectiveness of idarucizumab in dabigatran-associated intracranial hemorrhage: an interrupted time series evaluation. (CANSSI Ontario Data Access Grant)

Co-Applicant:
1. Reducing Gastrointestinal Bleeding with Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism (RADIANT) Pilot Randomized Trial

2. From questions to answers: Creation of meaningful, patient-orientated research to address the top unanswered research questions in Venous Thromboembolism- the Clot Top 10 priorities

Related Research at The Ottawa Hospital