Thrombosis / thromboembolism
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The Ottawa Hospital’s Thrombosis Program is a centre of excellence in both clinical research and clinical care of thrombosis related illness. We are devoted to generating practice-changing knowledge in the areas of diagnosis, treatment and prevention of deep vein thrombosis and pulmonary embolism (venous thromboembolism).
Thrombosis Program’s Mission
The primary mission of the program is to energetically better the lives of patients with venous thromboembolic disease. This is accomplished through:
- the design, conduct and dissemination of practice-changing clinical research
- education of the next generation of leaders in Adult Thrombosis Medicine (expert clinicians, educators and researchers)
- the delivery of quality cost-effective care to patients with venous thromboembolic disease in the Ottawa region
Thrombosis Program’s Vision
It is our vision to be world leaders in developing practice-changing knowledge generation in the areas of venous thromboembolism. Our group has a strongly established presence in the development of patient-oriented research on diagnostic algorithms for suspected deep vein thrombosis and suspected pulmonary embolism and cancer-associated thrombosis. We are growing an important research program on the management of anticoagulant-related bleeding complications. We also seek to be leaders in the next generation of experts in venous thromboembolism through our Area of Focussed Competency (AFC) Adult Thrombosis Medicine Fellowship (Clinical and Research Fellowship Programs). Finally, and importantly, we seek to deliver cost-effective quality care to patients with venous thromboembolism in the Ottawa region through the development of an Ottawa Regional Clinical Thrombosis Program with arms of the program including thromboembolism management, peri-operative anticoagulation and oral anticoagulation management.
Research & News
Labs and Groups
These research teams may include multiple scientists, investigators, staff and trainees all working towards a common goal, or they can represent a single scientist and their team.
Burger Lab
HERO Group (Dr. Thavorn)
Clinical Trials
The following list of clinical trials at The Ottawa Hospital is pulled from ClinicalTrials.gov, which is hosted by the U.S. National Library of Medicine and only available in English. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. If you email the study team directly, we can guarantee a response. Learn more about participating in research and clinical trials.
Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis (NCT06603870)
Venous Thromboembolism, Cancer, Upper Extremity Deep Vein Thrombosis, Catheter-Related Infections View DetailsA Pilot Trial Comparing Full Dose Rivaroxaban to Prophylactic Dose Rivaroxaban in Patients With Superficial Vein Thrombosis in the Leg (NCT06965998)
SVT, Thrombosis, Superficial Vein Thrombosis View DetailsReducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism (NCT06393868)
Venous Thromboembolism, Gastro Intestinal Bleeding, Blood Clot View DetailsPrimary Thromboprophylaxis in Patients With Malignancy and Central Venous Catheters (NCT05029063)
Venous Thromboembolism, Cancer View DetailsStatins for Venous Event Reduction in Patients With Venous Thromboembolism (NCT04319627)
Venous Thromboembolism, Blood Clot, Post Thrombotic Syndrome View DetailsClinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism (NCT04263038)
Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases, Cardiovascular Diseases, Respiratory Tract Diseases, Venous Thromboembolism, Anticoagulant-induced Bleeding, Bleeding View DetailsPROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) (NCT03559114)
Traumatic Brain Injury View DetailsDevelopment of a Risk Stratification Score for Recurrent Venous Thromboembolism and Treatment-related Clinically Relevant Bleeding in Patients With Cancer-associated Thrombosis (NCT06894576)
Cancer-associated Thrombosis View DetailsVTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy (NCT05920343)
Venous Thromboembolism, Urologic Cancer View DetailsA Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE (NCT05171075)
Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism View DetailsScreening for Occult Malignancy in Patients with Unprovoked Venous Thromboembolism (NCT04304651)
Embolism and Thrombosis View DetailsColchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial) (NCT06440694)
Venous Thromboembolism View DetailsPRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism (NCT05756244)
Pregnancy Related, Venous Thromboembolism View DetailsLow INR to Minimize Bleeding With Mechanical Valves Trial (NCT03636295)
Bleeding Post-mechanical Valve Replacement, Thromboembolism Post-mechanical Valve Replacement View DetailsPublications
The following research publications from The Ottawa Hospital are pulled from PubMed, with publication date of 2020 or later. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.
A Multicenter Prospective Cohort Study on the Use of Weight-Adjusted Dalteparin in Patients Over 90 kg With Acute Cancer-Associated Venous Thromboembolism-The WAVe Study.
2026-01-01 Go to publicationPredictors of clinically relevant bleeding during extended anticoagulation for cancer-associated venous thromboembolism (API-CAT): a post-hoc analysis of a randomised, non-inferiority trial.
2025-12-06 Go to publicationSafety and efficiency of D-dimer testing in combination with clinical decision rules to exclude pulmonary embolism in patients with cancer: individual patient data meta-analysis.
2025-12-05 Go to publicationImplementation failure: thromboprophylaxis in ambulatory patients with cancer.
2025-12-05 Go to publicationMajor Bleeding With Apixaban vs Aspirin: A Subanalysis of the ARTESiA Randomized Clinical Trial.
2025-12-01 Go to publication