Lung cancer
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Researchers at The Ottawa Hospital are investigating promising new approaches to prevent, diagnose and treat lung cancer. This page includes selected news stories about our lung cancer research, links to researchers working in this area and related resources.
Research & News
Labs and Groups
These research teams may include multiple scientists, investigators, staff and trainees all working towards a common goal, or they can represent a single scientist and their team.
Addison Cancer Research Lab
Ardolino Cancer Immunology Lab
Gray Lab
Clinical Trials
The following list of clinical trials at The Ottawa Hospital is pulled from ClinicalTrials.gov, which is hosted by the U.S. National Library of Medicine and only available in English. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. If you email the study team directly, we can guarantee a response. Learn more about participating in research and clinical trials.
Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung Cancer (NCT05849129)
Lung Cancer View DetailsMOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors (NCT06586515)
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, Colorectal Cancer View DetailsThe Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III (NCT04871412)
Lung Cancer, Gastric Cancer, Esophageal Cancer View DetailsA Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors (NCT06131840)
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Pancreatic Ductal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Small Cell Lung Carcinoma View DetailsOsimertinib Then Chemotherapy in EGFR-mutated Lung Cancer with Osimertinib Third-line Rechallenge (NCT04335292)
Non-Small Cell Lung Cancer View DetailsStudy of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC (NCT04093167)
Non-Small Cell Lung Cancer View DetailsPhase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 (NCT04613596)
Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer View DetailsA Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors (NCT06618287)
Lung Cancer, Breast Cancer View DetailsJoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer (NCT02468024)
Non-Small Cell Lung Cancer View DetailsA Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation (NCT05789082)
Non-Small Cell Lung Cancer View DetailsA Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors (NCT05538130)
Melanoma, Glioma, Thyroid Cancer, Non-Small Cell Lung Cancer, Malignant Neoplasms, Brain Neoplasms, Colorectal Cancer View DetailsA Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. (NCT05355701)
Melanoma, Non-Small-Cell Lung Cancer, Thyroid Cancer, Glioma, Advanced Colorectal Cancer (Part 1) View DetailsA Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers (NCT04260802)
Cancer, Neoplasms, Metastatic Cancer, Triple Negative Breast Cancer, Gastric Cancer, Cervical Cancer, Ovarian Cancer, Hepatocellular Carcinoma, Squamous Cell Carcinoma of Head and Neck, Urothelial Carcinoma, Urothelial Neoplasm, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Locally Advanced Solid Tumor, Locally Advanced Malignant Neoplasm, Squamous Cell Carcinoma, Sarcoma, Merkel Cell Carcinoma, Bladder Cancer View DetailsA Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors (NCT04895709)
Cervical Cancer, Gastric/Gastroesophageal Junction Adenocarcinoma, Microsatellite Stable Colorectal Cancer, Non-Small-Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Urothelial Carcinoma, Pancreatic Adenocarcinoma, Melanoma, Ovarian Neoplasms, Triple Negative Breast Neoplasms View DetailsOntario-wide Cancer TArgeted Nucleic Acid Evaluation (NCT02906943)
Breast Cancer, Lung Cancer, Colorectal Cancer, Melanoma, Gynecological Cancer, Genitourinary Cancer, Pancreatobiliary Cancer, Gastrointestinal Cancer, Head and Neck Cancer, Rare Cancer, Unknown Primary Cancer View DetailsTesting the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer (NCT05624996)
Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8 View DetailsPublications
The following research publications from The Ottawa Hospital are pulled from PubMed, with publication date of 2020 or later. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.
Coronary artery calcium on lung cancer screening-CT: An opportunity to optimize cardiovascular disease risk reduction.
2025-10-21 Go to publicationTarlatamab population survival kinetics in extensive-stage small cell lung cancer: brief report.
2025-12-01 Go to publicationIdentification of novel collagen breakdown products by human osteoclasts in vitro and in vivo.
2025-10-11 Go to publicationPhase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers.
2025-12-01 Go to publication