Flow Cytometry and Cell Sorting Facility
Publications
2024
Tur S, Palii CG, Brand M. Cell fate decision in erythropoiesis: Insights from multiomics studies. Exp Hematol. 2024 Mar;131:104167. doi: 10.1016/j.exphem.2024.104167. Epub 2024 Jan 21. PMID: 38262486; PMCID: PMC10939800.
Cairns G, Thumiah-Mootoo M, Abbasi MR, Gourlay M, Racine J, Larionov N, Prola A, Khacho M, Burelle Y. PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity. Stem Cell Reports. 2024 May 14;19(5):673-688. doi: 10.1016/j.stemcr.2024.03.004. Epub 2024 Apr 4. PMID: 38579709; PMCID: PMC11103785.
Burke Schinkel SC, Barros PO, Berthoud T, Byrareddy SN, McGuinty M, Cameron DW, Angel JB. Comparative analysis of human gut- and blood-derived mononuclear cells: contrasts in function and phenotype. Front Immunol. 2024 Feb 20;15:1336480. doi: 10.3389/fimmu.2024.1336480. PMID: 38444848; PMCID: PMC10912472.
Hodgins JJ, Abou-Hamad J, O'Dwyer CE, Hagerman A, Yakubovich E, Tanese de Souza C, Marotel M, Buchler A, Fadel S, Park MM, Fong-McMaster C, Crupi MF, Makinson OJ, Kurdieh R, Rezaei R, Dhillon HS, Ilkow CS, Bell JC, Harper ME, Rotstein BH, Auer RC, Vanderhyden BC, Sabourin LA, Bourgeois-Daigneault MC, Cook DP, Ardolino M. PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway. J Exp Med. 2024 Jul 1;221(7):e20221721. doi: 10.1084/jem.20221721. Epub 2024 Jun 13. PMID: 38869480; PMCID: PMC11176258.
Rakotoharisoa RV, Seifinoferest B, Zarifi N, Miller JDM, Rodriguez JM, Thompson MC, Chica RA. Design of Efficient Artificial Enzymes Using Crystallographically Enhanced Conformational Sampling. J Am Chem Soc. 2024 Apr 10;146(14):10001-10013. doi: 10.1021/jacs.4c00677. Epub 2024 Mar 26. PMID: 38532610.
Cyr-Depauw C, Cook DP, Mižik I, Lesage F, Vadivel A, Renesme L, Deng Y, Zhong S, Bardin P, Xu L, Möbius MA, Marzahn J, Freund D, Stewart DJ, Vanderhyden BC, Rüdiger M, Thébaud B. Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells. Am J Respir Crit Care Med. 2024 Apr 2. doi: 10.1164/rccm.202310-1975OC. Epub ahead of print. PMID: 38564376.
Iqbal MA, Bilen M, Liu Y, Jabre V, Fong BC, Chakroun I, Paul S, Chen J, Wade S, Kanaan M, Harper ME, Khacho M, Slack RS. The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration. Aging Cell. 2024 Jul;23(7):e14165. doi: 10.1111/acel.14165. Epub 2024 May 16. PMID: 38757355; PMCID: PMC11258489.
2023
Taha M, Arnaud T, Lightly TJ, Peters D, Wang L, Chen W, Cook BWM, Theriault SS, Abdelbary H. Combining bacteriophage and vancomycin is efficacious against MRSA biofilm-like aggregates formed in synovial fluid. Front Med (Lausanne). 2023 Jun 9;10:1134912. doi: 10.3389/fmed.2023.1134912. PMID: 37359001; PMCID: PMC10289194.
Swaminathan S, Scorza T, Yero A, Farnos O, Burke Schinkel SC, Angel JB, Jenabian MA. Impact of in vitro HIV infection on human thymic regulatory T cell differentiation. Front Microbiol. 2023 Jul 20;14:1217801. doi: 10.3389/fmicb.2023.1217801. PMID: 37547675; PMCID: PMC10400333.
Boulton S, Poutou J, Gill R, Alluqmani N, He X, Singaravelu R, Crupi MJF, Petryk J, Austin B, Angka L, Taha Z, Teo I, Singh S, Jamil R, Marius R, Martin N, Jamieson T, Azad T, Diallo JS, Ilkow CS, Bell JC. A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection. Mol Ther Methods Clin Dev. 2023 Sep 16;31:101110. doi: 10.1016/j.omtm.2023.101110. PMID: 37822719; PMCID: PMC10562195.
Alwithenani A, Taha Z, Thomson M, Chen A, Wong B, Arulanandam R, Diallo JS. Unlocking the potential of dimethyl fumarate: enhancing oncolytic HSV-1 efficacy for wider cancer applications. Front Immunol. 2023 Dec 19;14:1332929. doi: 10.3389/fimmu.2023.1332929. PMID: 38169670; PMCID: PMC10758402.
Wong B, Bergeron A, Maznyi G, Ng K, Jirovec A, Birdi HK, Serrano D, Spinelli M, Thomson M, Taha Z, Alwithenani A, Chen A, Lorimer I, Vanderhyden B, Arulanandam R, Diallo JS. Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, sensitizes cancer cells to VSVΔ51 oncolytic virotherapy. Mol Ther. 2023 Nov 1;31(11):3176-3192. doi: 10.1016/j.ymthe.2023.09.017. Epub 2023 Sep 27. PMID: 37766429; PMCID: PMC10638453.
Taha Z, Crupi MJF, Alluqmani N, Fareez F, Ng K, Sobh J, Lee E, Chen A, Thomson M, Spinelli MM, Ilkow CS, Bell JC, Arulanandam R, Diallo JS. Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus. Front Immunol. 2023 Apr 19;14:1181014. doi: 10.3389/fimmu.2023.1181014. PMID: 37153626; PMCID: PMC10154558.
Wong B, Birtch R, Rezaei R, Jamieson T, Crupi MJF, Diallo JS, Ilkow CS. Optimal delivery of RNA interference by viral vectors for cancer therapy. Mol Ther. 2023 Nov 1;31(11):3127-3145. doi: 10.1016/j.ymthe.2023.09.012. Epub 2023 Sep 20. PMID: 37735876; PMCID: PMC10638062.
Jennings VA, Ilkow CS. Generation and Quantification of Cytotoxic Lymphocytes Following Oncolytic Virus Infection of Multi-cellular Tumor Spheroids. Methods Mol Biol. 2023;2614:139-149. doi: 10.1007/978-1-0716-2914-7_10. PMID: 36587124.
Triolo M, Wade S, Baker N, Khacho M. Evaluating mitochondrial length, volume, and cristae ultrastructure in rare mouse adult stem cell populations. STAR Protoc. 2023 Mar 17;4(1):102107. doi: 10.1016/j.xpro.2023.102107. Epub 2023 Feb 9. PMID: 36853728; PMCID: PMC9943866.
Chen W, Perkins TJ, Rudnicki MA. Quantification of Muscle Satellite Stem Cell Divisions by High-Content Analysis. Methods Mol Biol. 2023;2587:537-553. doi: 10.1007/978-1-0716-2772-3_29. PMID: 36401049.
Esper ME, Kodippili K, Rudnicki MA. Immunofluorescence Labeling of Skeletal Muscle in Development, Regeneration, and Disease. Methods Mol Biol. 2023;2566:113-132. doi: 10.1007/978-1-0716-2675-7_9. PMID: 36152246; PMCID: PMC10204082.
Abou-Hamad J, Hodgins JJ, Yakubovich E, Vanderhyden BC, Ardolino M, Sabourin LA. Sox10-Deficient Drug-Resistant Melanoma Cells Are Refractory to Oncolytic RNA Viruses. Cells. 2023 Dec 29;13(1):73. doi: 10.3390/cells13010073. PMID: 38201278; PMCID: PMC10777920.
Collao N, D'Souza D, Messeiller L, Pilon E, Lloyd J, Larkin J, Ngu M, Cuillerier A, Green AE, Menzies KJ, Burelle Y, De Lisio M. Radiation induces long-term muscle fibrosis and promotes a fibrotic phenotype in fibro-adipogenic progenitors. J Cachexia Sarcopenia Muscle. 2023 Oct;14(5):2335-2349. doi: 10.1002/jcsm.13320. Epub 2023 Sep 6. PMID: 37671686; PMCID: PMC10570115.
Liu Y, Bilen M, McNicoll MM, Harris RA, Fong BC, Iqbal MA, Paul S, Mayne J, Walker K, Wang J, Figeys D, Slack RS. Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer's disease. Cell Death Dis. 2023 Feb 18;14(2):138. doi: 10.1038/s41419-023-05650-1. PMID: 36801910; PMCID: PMC9938901.
Godoy RS, Cober ND, Cook DP, McCourt E, Deng Y, Wang L, Schlosser K, Rowe K, Stewart DJ. Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation. Elife. 2023 Apr 20;12:e80900. doi: 10.7554/eLife.80900. PMID: 37078698; PMCID: PMC10181823.
Tennakoon G, Auer R. "Don't let it to air": A cautionary tale of the potential consequences of surgery of residual cancer. Brain Behav Immun. 2023 Jul;111:247-248. doi: 10.1016/j.bbi.2023.04.012. Epub 2023 Apr 29. PMID: 37127226.
Ngubo M, Moradi F, Ito CY, Stanford WL. Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2. Genes (Basel). 2023 Sep 27;14(10):1879. doi: 10.3390/genes14101879. PMID: 37895228; PMCID: PMC10606531.
Taha M, Arulanandam R, Chen A, Diallo JS, Abdelbary H. Combining povidone-iodine with vancomycin can be beneficial in reducing early biofilm formation of methicillin-resistant Staphylococcus aureus and methicillin-sensitive S. aureus on titanium surface. J Biomed Mater Res B Appl Biomater. 2023 May;111(5):1133-1141. doi: 10.1002/jbm.b.35220. Epub 2023 Jan 11. PMID: 36632686.
2022
Cortés-Kaplan S, Kurdieh R, Hasim MS, Kaczmarek S, Taha Z, Maznyi G, McComb S, Lee SH, Diallo JS, Ardolino M. A New Functional Screening Platform Identifies Colistin Sulfate as an Enhancer of Natural Killer Cell Cytotoxicity. Cancers (Basel). 2022 Jun 8;14(12):2832. doi: 10.3390/cancers14122832. PMID: 35740500; PMCID: PMC9221353.
Hasim MS, Marotel M, Hodgins JJ, Vulpis E, Makinson OJ, Asif S, Shih HY, Scheer AK, MacMillan O, Alonso FG, Burke KP, Cook DP, Li R, Petrucci MT, Santoni A, Fallon PG, Sharpe AH, Sciumè G, Veillette A, Zingoni A, Gray DA, McCurdy A, Ardolino M. When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer. Sci Adv. 2022 Apr 15;8(15):eabj3286. doi: 10.1126/sciadv.abj3286. Epub 2022 Apr 13. PMID: 35417234; PMCID: PMC9007500.
Abou-Hamad J, Hodgins JJ, de Souza CT, Garland B, Labrèche C, Marotel M, Gibson C, Delisle S, Pascoal J, Auer RC, Ardolino M, Sabourin LA. CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness. iScience. 2022 Nov 7;25(12):105524. doi: 10.1016/j.isci.2022.105524. PMID: 36437876; PMCID: PMC9682343.
Market M, Tennakoon G, Scaffidi M, Cook DP, Angka L, Ng J, Tanese de Souza C, Kennedy MA, Vanderhyden BC, Auer RC. Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics. Int J Mol Sci. 2022 Nov 23;23(23):14608. doi: 10.3390/ijms232314608. PMID: 36498937; PMCID: PMC9737532.
Nakka K, Hachmer S, Mokhtari Z, Kovac R, Bandukwala H, Bernard C, Li Y, Xie G, Liu C, Fallahi M, Megeney LA, Gondin J, Chazaud B, Brand M, Zha X, Ge K, Dilworth FJ. JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment. Science. 2022 Aug 5;377(6606):666-669. doi: 10.1126/science.abm9735. Epub 2022 Aug 4. PMID: 35926054.
Baker N, Wade S, Triolo M, Girgis J, Chwastek D, Larrigan S, Feige P, Fujita R, Crist C, Rudnicki MA, Burelle Y, Khacho M. The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells. Cell Stem Cell. 2022 Sep 1;29(9):1315-1332.e9. doi: 10.1016/j.stem.2022.07.010. Epub 2022 Aug 22. PMID: 35998642; PMCID: PMC10249109.
Wade S, Khacho M. MITOCHONDRIA: Mitochondrial dynamics in the regulation of stem cells. Int J Biochem Cell Biol. 2022 Mar;144:106158. doi: 10.1016/j.biocel.2022.106158. Epub 2022 Jan 19. PMID: 35063637.
Brun CE, Sincennes MC, Lin AYT, Hall D, Jarassier W, Feige P, Le Grand F, Rudnicki MA. GLI3 regulates muscle stem cell entry into GAlert and self-renewal. Nat Commun. 2022 Jul 8;13(1):3961. doi: 10.1038/s41467-022-31695-5. PMID: 35803939; PMCID: PMC9270324.
Saber J, Rudnicki MA. Carm1 and the Epigenetic Control of Stem Cell Function. Stem Cells Transl Med. 2022 Nov 18;11(11):1143-1150. doi: 10.1093/stcltm/szac068. PMID: 36103286; PMCID: PMC9672848.
Hekmatnejad B, Rudnicki MA. Transplantation to study satellite cell heterogeneity in skeletal muscle. Front Cell Dev Biol. 2022 Aug 24;10:902225. doi: 10.3389/fcell.2022.902225. PMID: 36092722; PMCID: PMC9448869.
Kalinina A, Lagace D. Single-Cell and Single-Nucleus RNAseq Analysis of Adult Neurogenesis. Cells. 2022 May 13;11(10):1633. doi: 10.3390/cells11101633. PMID: 35626670; PMCID: PMC9139993.
Iqbal MA, Fong BC, Slack RS. Direct FACS Isolation of Neural Stem/Progenitor Lineages from the Adult Brain. Methods Mol Biol. 2022;2515:117-127. doi: 10.1007/978-1-0716-2409-8_8. PMID: 35776349.
Pietrobon A, Yockell-Lelièvre J, Flood TA, Stanford WL. Renal organoid modeling of tuberous sclerosis complex reveals lesion features arise from diverse developmental processes. Cell Rep. 2022 Jul 5;40(1):111048. doi: 10.1016/j.celrep.2022.111048. PMID: 35793620.
Rodriguez GM, Galpin KJC, Cook DP, Yakubovich E, Maranda V, Macdonald EA, Wilson-Sanchez J, Thomas AL, Burdette JE, Vanderhyden BC. The Tumor Immune Profile of Murine Ovarian Cancer Models: An Essential Tool For Ovarian Cancer Immunotherapy Research. Cancer Res Commun. 2022 Jun;2(6):417-433. doi: 10.1158/2767-9764.crc-22-0017. Epub 2022 Jun 9. PMID: 36311166; PMCID: PMC9616009.
Landry DA, Yakubovich E, Cook DP, Fasih S, Upham J, Vanderhyden BC. Metformin prevents age-associated ovarian fibrosis by modulating the immune landscape in female mice. Sci Adv. 2022 Sep 2;8(35):eabq1475. doi: 10.1126/sciadv.abq1475. Epub 2022 Sep 2. PMID: 36054356.
Durlak W, Thébaud B. The vascular phenotype of BPD: new basic science insights-new precision medicine approaches. Pediatr Res. 2022 Dec 22. doi: 10.1038/s41390-022-02428-7. Epub ahead of print. PMID: 36550351.
Mižíková I, Lesage F, Cyr-Depauw C, Cook DP, Hurskainen M, Hänninen SM, Vadivel A, Bardin P, Zhong S, Carpén O, Vanderhyden BC, Thébaud B. Single-Cell RNA Sequencing-Based Characterization of Resident Lung Mesenchymal Stromal Cells in Bronchopulmonary Dysplasia. Stem Cells. 2022 May 27;40(5):479-492. doi: 10.1093/stmcls/sxab023. PMID: 35445270; PMCID: PMC9199848.
Lesage F, Thébaud B. Mesenchymal Stromal Cell-Derived Extracellular Vesicles for Neonatal Lung Disease: Tiny Particles, Major Promise, Rigorous Requirements for Clinical Translation. Cells. 2022 Mar 31;11(7):1176. doi: 10.3390/cells11071176. PMID: 35406742; PMCID: PMC8997376.
2021
Robinson DCL, Ritso M, Nelson GM, Mokhtari Z, Nakka K, Bandukwala H, Goldman SR, Park PJ, Mounier R, Chazaud B, Brand M, Rudnicki MA, Adelman K, Dilworth FJ. Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation. Dev Cell. 2021 Apr 5;56(7):1014-1029.e7. doi: 10.1016/j.devcel.2021.02.025. Epub 2021 Mar 17. PMID: 33735618; PMCID: PMC8357161.
Li Y, Nakka K, Olender T, Gingras-Gelinas P, Wong MM, Robinson DCL, Bandukwala H, Palii CG, Neyret O, Brand M, Blais A, Dilworth FJ. Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag. STAR Protoc. 2021 Aug 19;2(3):100751. doi: 10.1016/j.xpro.2021.100751. PMID: 34467227; PMCID: PMC8384913.
Sincennes MC, Brun CE, Lin AYT, Rosembert T, Datzkiw D, Saber J, Ming H, Kawabe YI, Rudnicki MA. Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice. Nat Commun. 2021 May 31;12(1):3253. doi: 10.1038/s41467-021-23577-z. PMID: 34059674; PMCID: PMC8167170.
Thumiah-Mootoo M, Podinic T, Khacho M. Assessment of Mitochondrial Reactive Oxygen Species and Redox Regulation in Stem Cells. Methods Mol Biol. 2021;2277:289-297. doi: 10.1007/978-1-0716-1270-5_18. PMID: 34080158.
Carter LE, Cook DP, McCloskey CW, Grondin MA, Landry DA, Dang T, Collins O, Gamwell LF, Dempster HA, Vanderhyden BC. Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium. Commun Biol. 2021 May 5;4(1):527. doi: 10.1038/s42003-021-02045-w. PMID: 33953351; PMCID: PMC8100130.
Hurskainen M, Mižíková I, Cook DP, Andersson N, Cyr-Depauw C, Lesage F, Helle E, Renesme L, Jankov RP, Heikinheimo M, Vanderhyden BC, Thébaud B. Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage. Nat Commun. 2021 Mar 10;12(1):1565. doi: 10.1038/s41467-021-21865-2. PMID: 33692365; PMCID: PMC7946947.
Pryce BR, Labrèche C, Hamoudi D, Abou-Hamad J, Al-Zahrani KN, Hodgins JJ, Boulanger-Piette A, Bossé S, Balog-Alvarez C, Frénette J, Ardolino M, Kornegay JN, Sabourin LA. Muscle-specific deletion of SLK/Stk2 enhances p38 activity and myogenesis in mdx mice. Biochim Biophys Acta Mol Cell Res. 2021 Feb;1868(2):118917. doi: 10.1016/j.bbamcr.2020.118917. Epub 2020 Nov 28. PMID: 33259860.
2020
Dupard SJ, Grigoryan A, Farhat S, Coutu DL, Bourgine PE. Development of Humanized Ossicles: Bridging the Hematopoietic Gap. Trends Mol Med. 2020 Jun;26(6):552-569. doi: 10.1016/j.molmed.2020.01.016. Epub 2020 Mar 3. PMID: 32470383.
Al-Zahrani, K.N., Abou-Hamad, J., Cook, D.P. et al. Loss of the Ste20-like kinase induces a basal/stem-like phenotype in HER2-positive breast cancers. Oncogene 39, 4592–4602 (2020).
Tian W, Alsaadi R, Guo Z, Kalinina A, Carrier M, Tremblay ME, Lacoste B, Lagace D, Russell RC. An antibody for analysis of autophagy induction. Nat Methods. 2020 Feb;17(2):232-239. doi: 10.1038/s41592-019-0661-y. Epub 2019 Nov 25. PMID: 31768061.
Feige P, Rudnicki MA. Isolation of satellite cells and transplantation into mice for lineage tracing in muscle. Nat Protoc. 2020 Mar;15(3):1082-1097. doi: 10.1038/s41596-019-0278-8. Epub 2020 Jan 22. PMID: 31965111.
Ritso M, Rudnicki MA. H19 lncRNA to dystrophin's rescue. Nat Cell Biol. 2020 Nov;22(11):1289-1290. doi: 10.1038/s41556-020-00598-2. PMID: 33106655.
2019
Wang YX, Feige P, Brun CE, Hekmatnejad B, Dumont NA, Renaud JM, Faulkes S, Guindon DE, Rudnicki MA. EGFR-Aurka Signaling Rescues Polarity and Regeneration Defects in Dystrophin-Deficient Muscle Stem Cells by Increasing Asymmetric Divisions. Cell Stem Cell (2019), https://doi.org/10.1016/j.stem.2019.01.002
Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran-Rodriguez U, Michaud J, Dammone G, Sizzano F, Mashinchian O, Ancel S, Migliavacca E, Liot S, Jacot G, Metairon S, Raymond F, Descombes P, Palini A, Chazaud B, Rudnicki MA, Bentzinger CF, Feige JN. Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors. Cell Stem Cell. 2019 Mar 7;24(3):433-446.e7. doi: 10.1016/j.stem.2018.12.014. Epub 2019 Jan 24.
2018
Feige P, Brun CE, Ritso M, Rudnicki MA. Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease. Cell Stem Cell. 2018 Nov 1;23(5):653-664. doi: 10.1016/j.stem.2018.10.006. Review. PubMed PMID: 30388423; PubMed Central PMCID: PMC6262894.
Soleimani VD, Nguyen D, Ramachandran P, Palidwor GA, Porter CJ, Yin H, Perkins TJ, Rudnicki MA. Cis-regulatory determinants of MyoD function. Nucleic Acids Res. 2018 Aug 21;46(14):7221-7235. doi: 10.1093/nar/gky388. PubMed PMID: 30016497; PubMed Central PMCID: PMC6101602.
Feige P, Rudnicki MA. Muscle stem cells. Curr Biol. 2018 May 21;28(10):R589-R590. doi: 10.1016/j.cub.2018.02.064. PubMed PMID: 29787715.
Bar-Nur O, Gerli MFM, Di Stefano B, Almada AE, Galvin A, Coffey A, Huebner AJ, Feige P, Verheul C, Cheung P, Payzin-Dogru D, Paisant S, Anselmo A, Sadreyev RI, Ott HC, Tajbakhsh S, Rudnicki MA, Wagers AJ, Hochedlinger K. Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors. Stem Cell Reports. 2018 May 8;10(5):1505-1521. doi: 10.1016/j.stemcr.2018.04.009. PubMed PMID: 29742392; PubMed Central PMCID: PMC5995754.
Chang NC, Sincennes MC, Chevalier FP, Brun CE, Lacaria M, Segalés J, Muñoz-Cánoves P, Ming H, Rudnicki MA. The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment. Cell Stem Cell. 2018 May 3;22(5):755-768.e6. doi: 10.1016/j.stem.2018.03.022. Epub 2018 Apr 19.
Brun CE, Wang YX, Rudnicki MA. Single EDL Myofiber Isolation for Analyses of Quiescent and Activated Muscle Stem Cells. Methods Mol Biol. 2018;1686:149-159. doi: 10.1007/978-1-4939-7371-2_11.
2017
Hernández-Hernández JM, García-González EG, Brun CE, Rudnicki MA. The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration. Semin Cell Dev Biol. 2017 Dec;72:10-18. doi: 10.1016/j.semcdb.2017.11.010
Fraineau S, Palii CG, McNeill B, Ritso M, Shelley WC, Prasain N, Chu A, Vion E, Rieck K, Nilufar S, Perkins TJ, Rudnicki MA, Allan DS, Yoder MC, Suuronen EJ, Brand M. Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis. Stem Cell Reports 2017 Nov 14;9(5):1573-1587. doi: 10.1016/j.stemcr.2017.09.009.
Lacour F, Vezin E, Bentzinger CF, Sincennes MC, Giordani L, Ferry A, Mitchell R, Patel K, Rudnicki MA, Chaboissier MC, Chassot AA, Le Grand F. R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways. Cell Rep. 2017 Mar 7;18(10):2320-2330. doi: 10.1016/j.celrep.2017.02.036. PubMed PMID: 28273449.
Sincennes MC, Wang YX, Rudnicki MA. Primary Mouse Myoblast Purification using Magnetic Cell Separation. Methods Mol Biol. 2017;1556:41-50. doi: 10.1007/978-1-4939-6771-1_3. PubMed PMID: 28247344.
Dumont NA, Rudnicki MA. Characterizing Satellite Cells and Myogenic Progenitors During Skeletal Muscle Regeneration. Methods Mol Biol. 2017;1560:179-188. doi: 10.1007/978-1-4939-6788-9_12. PubMed PMID: 28155153.
2016
Lukjanenko L, Jung MJ, Hegde N, Perruisseau-Carrier C, Migliavacca E, Rozo M, Karaz S, Jacot G, Schmidt M, Li L, Metairon S, Raymond F, Lee U, Sizzano F, Wilson DH, Dumont NA, Palini A, Fässler R, Steiner P, Descombes P, Rudnicki MA, Fan CM, von Maltzahn J, Feige JN, Bentzinger CF. Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nat Med. 2016 Aug;22(8):897-905. doi: 10.1038/nm.4126. Epub 2016 Jul 4. PubMed PMID: 27376579.
Pasut A, Chang NC, Rodriguez UG, Faulkes S, Yin H, Lacaria M, Ming H, Rudnicki MA. Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation. Cell Rep. 2016 Jul 12;16(2):333 43. doi: 10.1016/j.celrep.2016.06.001. Epub 2016 Jun 23. PubMed PMID: 27346341
Jahani-Asl A, Yin H, Soleimani VD, Haque T, Luchman HA, Chang NC, Sincennes MC, Puram SV, Scott AM, Lorimer IA, Perkins TJ, Ligon KL, Weiss S, Rudnicki MA, Bonni A. Control of glioblastoma tumorigenesis by feed-forward cytokine signaling. Nat Neurosci. 2016 Jun;19(6):798-806. doi: 10.1038/nn.4295. Epub 2016 Apr 25. PubMed PMID: 27110918
Harper SC, Brack A, MacDonnell S, Franti M, Olwin BB, Bailey BA, Rudnicki MA, Houser SR. Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects? Circ Res. 2016 Apr 1;118(7):1143-50; discussion 1150. doi: 10.1161/CIRCRESAHA.116.307962. PubMed PMID: 27034276
2015
Chihara D, Romer AI, Bentzinger CF, Rudnicki MA, Krauss RS. PAX7 is required for patterning the esophageal musculature. Skelet Muscle. 2015 Dec 3;5:39. doi: 10.1186/s13395-015-0068-0. eCollection 2015 Dec 3. PubMed PMID: 26635949; PubMed Central PMCID: PMC4668666.
Dumont NA, Wang YX, von Maltzahn J, Pasut A, Bentzinger CF, Brun CE, Rudnicki MA. Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division. Nat Med. 2015 Dec;21(12):1455-63. doi: 10.1038/nm.3990. Epub 2015 Nov 16. PubMed PMID: 26569381; PubMed Central PMCID: PMC4839960.
Dick SA, Chang NC, Dumont NA, Bell RA, Putinski C, Kawabe Y, Litchfield DW, Rudnicki MA, Megeney LA. Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5246-52. doi: 10.1073/pnas.1512869112. Epub 2015 Sep 8. PubMed PMID: 26372956; PubMed Central PMCID: PMC4586827.
Jones AE, Price FD, Le Grand F, Soleimani VD, Dick SA, Megeney LA, Rudnicki MA. Wnt/ß-catenin controls follistatin signalling to regulate satellite cell myogenic potential. Skelet Muscle. 2015 Apr 28;5:14. doi: 10.1186/s13395-015-0038-6. eCollection 2015 Apr 28. PubMed PMID: 25949788; PubMed Central PMCID: PMC4421991.
Price FD, von Maltzahn J, Bentzinger CF, Dumont NA, Yin H, Chang NC, Wilson DH, Frenette J, Rudnicki MA. Corrigendum: Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat Med. 2015 Apr;21(4):414. doi: 10.1038/nm0415-414a. PubMed PMID: 25849274.
2014
Smid JK, Faulkes S, Rudnicki MA. Periostin induces pancreatic regeneration. Endocrinology. 2015 Mar;156(3):824-36. doi: 10.1210/en.2014-1637. Epub 2014 Dec 8. PubMed PMID: 25485969.
Price FD, von Maltzahn J, Bentzinger CF, Dumont NA, Yin H, Chang NC, Wilson DH, Frenette J, Rudnicki MA. Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat Med. 2014 Oct;20(10):1174-81. doi: 10.1038/nm.3655. Epub 2014 Sep 7. Erratum in: Nat Med. 2015 Apr;21(4):414. Nat Med. 2014 Oct;(10):1217. PubMed PMID: 25194569; PubMed Central PMCID: PMC4191983.
Jiang C, Wen Y, Kuroda K, Hannon K, Rudnicki MA, Kuang S. Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy. Dis Model Mech. 2014 Aug;7(8):997-1004. doi: 10.1242/dmm.015917. Epub 2014 Jun 6. PubMed PMID: 24906372; PubMed Central PMCID: PMC4107328.
Bentzinger CF, von Maltzahn J, Dumont NA, Stark DA, Wang YX, Nhan K, Frenette J, Cornelison DD, Rudnicki MA. Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J Cell Biol. 2014 Apr 14;205(1):97-111. doi: 10.1083/jcb.201310035. Epub 2014 Apr 7. PubMed PMID: 24711502; PubMed Central PMCID: PMC3987134.
2013
von Maltzahn J, Zinoviev R, Chang NC, Bentzinger CF, Rudnicki MA. A truncated Wnt7a retains full biological activity in skeletal muscle. Nat Commun. 2013;4:2869. doi: 10.1038/ncomms3869. PubMed PMID: 24287629; PubMed Central PMCID: PMC3868162.
He WA, Berardi E, Cardillo VM, Acharyya S, Aulino P, Thomas-Ahner J, Wang J, Bloomston M, Muscarella P, Nau P, Shah N, Butchbach ME, Ladner K, Adamo S, Rudnicki MA, Keller C, Coletti D, Montanaro F, Guttridge DC. NF-?B-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia. J Clin Invest. 2013 Nov;123(11):4821-35. PubMed PMID: 24084740; PubMed Central PMCID: PMC3809785.
von Maltzahn J, Jones AE, Parks RJ, Rudnicki MA. Pax7 is critical for the normal function of satellite cells in adult skeletal muscle. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16474-9. doi: 10.1073/pnas.1307680110. Epub 2013 Sep 24. PubMed PMID: 24065826; PubMed Central PMCID: PMC3799311.
Liu W, Bi P, Shan T, Yang X, Yin H, Wang YX, Liu N, Rudnicki MA, Kuang S. miR-133a regulates adipocyte browning in vivo. PLoS Genet. 2013;9(7):e1003626. doi: 10.1371/journal.pgen.1003626. Epub 2013 Jul 11. PubMed PMID: 23874225; PubMed Central PMCID: PMC3708806.
Parker MH, von Maltzahn J, Bakkar N, Al-Joubori B, Ishibashi J, Guttridge D, Rudnicki MA. Retraction: MyoD-dependent regulation of NF-?B activity couples cell-cycle withdrawal to myogenic differentiation. Skelet Muscle. 2013 Jul 18;3(1):15. doi: 10.1186/2044-5040-3-15. PubMed PMID: 23870549; PubMed Central PMCID: PMC3717048.
Soleimani VD, Palidwor GA, Ramachandran P, Perkins TJ, Rudnicki MA. Chromatin tandem affinity purification sequencing. Nat Protoc. 2013 Aug;8(8):1525-34. doi: 10.1038/nprot.2013.088. Epub 2013 Jul 11. PubMed PMID: 23845964; PubMed Central PMCID: PMC4058862.
Wang YX, Bentzinger CF, Rudnicki MA. Treating muscular dystrophy by stimulating intrinsic repair. Regen Med. 2013 May;8(3):237-40. doi: 10.2217/rme.13.27. PubMed PMID: 23627818.
Pasut A, Jones AE, Rudnicki MA. Isolation and culture of individual myofibers and their satellite cells from adult skeletal muscle. J Vis Exp. 2013 Mar 22;(73):e50074. doi: 10.3791/50074. PubMed PMID: 23542587; PubMed Central PMCID: PMC3639710.
Kuroda K, Kuang S, Taketo MM, Rudnicki MA. Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts. Skelet Muscle. 2013 Mar 5;3(1):5. doi: 10.1186/2044-5040-3-5. PubMed PMID: 23497616; PubMed Central PMCID: PMC3602004.
Campbell PA, Rudnicki MA. Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency. Stem Cells. 2013 Jun;31(6):1107-20. doi: 10.1002/stem.1365. PubMed PMID: 23495099.
Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel R, Harper ME, Rudnicki MA. MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab. 2013 Feb 5;17(2):210-24. doi: 10.1016/j.cmet.2013.01.004. PubMed PMID: 23395168; PubMed Central PMCID: PMC3641657.
Price FD, Yin H, Jones A, van Ijcken W, Grosveld F, Rudnicki MA. Canonical Wnt signaling induces a primitive endoderm metastable state in mouse embryonic stem cells. Stem Cells. 2013 Apr;31(4):752-64. doi: 10.1002/stem.1321. PubMed PMID: 23307624.
Bentzinger CF, Wang YX, von Maltzahn J, Soleimani VD, Yin H, Rudnicki MA. Fibronectin regulates Wnt7a signaling and satellite cell expansion. Cell Stem Cell. 2013 Jan 3;12(1):75-87. doi: 10.1016/j.stem.2012.09.015. PubMed PMID: 23290138; PubMed Central PMCID: PMC3539137.
2012
Wang YX, Bentzinger CF, Rudnicki MA. Molecular regulation of determination in asymmetrically dividing muscle stem cells. Cell Cycle. 2013 Jan 1;12(1):3-4. doi: 10.4161/cc.23068. Epub 2012 Dec 19. PubMed PMID: 23255099; PubMed Central PMCID: PMC3570513.
von Maltzahn J, Renaud JM, Parise G, Rudnicki MA. Wnt7a treatment ameliorates muscular dystrophy. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20614-9. doi: 10.1073/pnas.1215765109. Epub 2012 Nov 26. PubMed PMID: 23185011; PubMed Central PMCID: PMC3528612.
Huh MS, Price O'Dea T, Ouazia D, McKay BC, Parise G, Parks RJ, Rudnicki MA, Picketts DJ. Compromised genomic integrity impedes muscle growth after Atrx inactivation. J Clin Invest. 2012 Dec;122(12):4412-23. doi: 10.1172/JCI63765. Epub 2012 Nov 1. PubMed PMID: 23114596; PubMed Central PMCID: PMC3533543.
Kawabe Y, Wang YX, McKinnell IW, Bedford MT, Rudnicki MA. Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions. Cell Stem Cell. 2012 Sep 7;11(3):333-45. doi: 10.1016/j.stem.2012.07.001. Epub 2012 Aug 2. PubMed PMID: 22863532; PubMed Central PMCID: PMC3438319.
Liu QC, Zha XH, Faralli H, Yin H, Louis-Jeune C, Perdiguero E, Pranckeviciene E, Muñoz-Cànoves P, Rudnicki MA, Brand M, Perez-Iratxeta C, Dilworth FJ. Comparative expression profiling identifies differential roles for Myogenin and p38a MAPK signaling in myogenesis. J Mol Cell Biol. 2012 Dec;4(6):386-97. doi: 10.1093/jmcb/mjs045. Epub 2012 Jul 30. PubMed PMID: 22847234; PubMed Central PMCID: PMC4580549.
Soleimani VD, Yin H, Jahani-Asl A, Ming H, Kockx CE, van Ijcken WF, Grosveld F, Rudnicki MA. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Mol Cell. 2012 Aug 10;47(3):457-68. doi: 10.1016/j.molcel.2012.05.046. Epub 2012 Jul 5. PubMed PMID: 22771117; PubMed Central PMCID: PMC4580277.
Rudnicki MA. Margaret Buckingham, discoveries in skeletal and cardiac muscle development, elected to the National Academy of Science. Skelet Muscle. 2012 Jun 7;2(1):12. doi: 10.1186/2044-5040-2-12. PubMed PMID: 22676886; PubMed Central PMCID: PMC3407767.
Soleimani VD, Punch VG, Kawabe Y, Jones AE, Palidwor GA, Porter CJ, Cross JW, Carvajal JJ, Kockx CE, van IJcken WF, Perkins TJ, Rigby PW, Grosveld F, Rudnicki MA. Transcriptional dominance of Pax7 in adult myogenesis is due to high-affinity recognition of homeodomain motifs. Dev Cell. 2012 Jun 12;22(6):1208-20. doi: 10.1016/j.devcel.2012.03.014. Epub 2012 May 17. PubMed PMID: 22609161; PubMed Central PMCID: PMC3376216.
Parker MH, von Maltzahn J, Bakkar N, Al-Joubori B, Ishibashi J, Guttridge D, Rudnicki MA. MyoD-dependent regulation of NF-?B activity couples cell-cycle withdrawal to myogenic differentiation. Skelet Muscle. 2012 May 19;2(1):6. doi: 10.1186/2044-5040-2-6. PubMed PMID: 22541644; PubMed Central PMCID: PMC3356597.
Yip DJ, Corcoran CP, Alvarez-Saavedra M, DeMaria A, Rennick S, Mears AJ, Rudnicki MA, Messier C, Picketts DJ. Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain. Dev Cell. 2012 Apr 17;22(4):871-8. doi: 10.1016/j.devcel.2012.01.020. PubMed PMID: 22516202; PubMed Central PMCID: PMC4580287.
Pasut A, Rudnicki MA. The long, the short, and the micro: a polyA tale of Pax3 in satellite cells. Cell Stem Cell. 2012 Mar 2;10(3):237-8. doi: 10.1016/j.stem.2012.02.009. PubMed PMID: 22385651; PubMed Central PMCID: PMC3300070.